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Steroid pulse therapy prevents restenosis following balloon dilatation for esophageal stricture
http://hdl.handle.net/2237/25144
http://hdl.handle.net/2237/251446cbb52c9-0ffd-4e68-9940-96519e7524d7
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2016-12-05 | |||||
タイトル | ||||||
タイトル | Steroid pulse therapy prevents restenosis following balloon dilatation for esophageal stricture | |||||
言語 | en | |||||
著者 |
Yokota, Kazuki
× Yokota, Kazuki× Uchida, Hiroo× Tanano, Akihide× Shirota, Chiyoe× Tainaka, Takahisa× Hinoki, Akinari× Murase, Naruhiko× Oshima, Kazuo× Shirotsuki, Ryo× Chiba, Kosuke |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | The final publication is available at Springer via http://doi.org/10.1007/s00383-016-3939-5 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Esophageal stricture | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Congenital esophageal stenosis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Balloon dilatation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Steroid pulse | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Systemic administration | |||||
抄録 | ||||||
内容記述 | Purpose: This study aimed to evaluate the effectiveness of intravenous steroid pulse therapy following balloon dilatation for esophageal stenosis and stricture in children. Methods: The study enrolled six children, including three with congenital esophageal stenosis and three with anastomotic strictures after surgery for esophageal atresia, all of whom were treated by balloon dilatation combined with high-dose intravenous methylprednisolone pulse therapy. Methylprednisolone was injected intravenously at a dose of 20 mg/kg/day for 2 days, starting from the day of dilatation, followed by 10 mg/kg/day for 2 days, for a total of 4 days. Results: Esophageal stricture recurred in all three patients with congenital esophageal stenosis despite repeated balloon dilatation without methylprednisolone. However, the symptoms of dysphagia improved and did not recur after systemic steroid pulse therapy following balloon dilatation. Symptoms also resolved in all three patients with anastomotic strictures following balloon dilatation with systemic steroid pulse therapy. All six patients remained asymptomatic after 6–21 months follow-up, with no complications. Conclusion: Intravenous methylprednisolone pulse therapy following balloon dilatation is safe and effective for the treatment of esophageal stenosis and strictures in children. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Springer | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプresource | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1007/s00383-016-3939-5 | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0179-0358 | |||||
書誌情報 |
en : Pediatric Surgery International 巻 32, 号 9, p. 875-879, 発行日 2016-09 |
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著者版フラグ | ||||||
値 | author | |||||
URI | ||||||
識別子 | http://doi.org/10.1007/s00383-016-3939-5 | |||||
識別子タイプ | DOI | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/25144 | |||||
識別子タイプ | HDL |