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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Steroid pulse therapy prevents restenosis following balloon dilatation for esophageal stricture

http://hdl.handle.net/2237/25144
6cbb52c9-0ffd-4e68-9940-96519e7524d7
名前 / ファイル ライセンス アクション
manuscript.pdf manuscript.pdf ファイル公開:2017/09/01 (684.3 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2016-12-05
タイトル
タイトル Steroid pulse therapy prevents restenosis following balloon dilatation for esophageal stricture
著者 Yokota, Kazuki

× Yokota, Kazuki

WEKO 67759

Yokota, Kazuki

Search repository
Uchida, Hiroo

× Uchida, Hiroo

WEKO 67760

Uchida, Hiroo

Search repository
Tanano, Akihide

× Tanano, Akihide

WEKO 67761

Tanano, Akihide

Search repository
Shirota, Chiyoe

× Shirota, Chiyoe

WEKO 67762

Shirota, Chiyoe

Search repository
Tainaka, Takahisa

× Tainaka, Takahisa

WEKO 67763

Tainaka, Takahisa

Search repository
Hinoki, Akinari

× Hinoki, Akinari

WEKO 67764

Hinoki, Akinari

Search repository
Murase, Naruhiko

× Murase, Naruhiko

WEKO 67765

Murase, Naruhiko

Search repository
Oshima, Kazuo

× Oshima, Kazuo

WEKO 67766

Oshima, Kazuo

Search repository
Shirotsuki, Ryo

× Shirotsuki, Ryo

WEKO 67767

Shirotsuki, Ryo

Search repository
Chiba, Kosuke

× Chiba, Kosuke

WEKO 67768

Chiba, Kosuke

Search repository
権利
権利情報 The final publication is available at Springer via http://doi.org/10.1007/s00383-016-3939-5
キーワード
主題Scheme Other
主題 Esophageal stricture
キーワード
主題Scheme Other
主題 Congenital esophageal stenosis
キーワード
主題Scheme Other
主題 Balloon dilatation
キーワード
主題Scheme Other
主題 Steroid pulse
キーワード
主題Scheme Other
主題 Systemic administration
抄録
内容記述 Purpose: This study aimed to evaluate the effectiveness of intravenous steroid pulse therapy following balloon dilatation for esophageal stenosis and stricture in children. Methods: The study enrolled six children, including three with congenital esophageal stenosis and three with anastomotic strictures after surgery for esophageal atresia, all of whom were treated by balloon dilatation combined with high-dose intravenous methylprednisolone pulse therapy. Methylprednisolone was injected intravenously at a dose of 20 mg/kg/day for 2 days, starting from the day of dilatation, followed by 10 mg/kg/day for 2 days, for a total of 4 days. Results: Esophageal stricture recurred in all three patients with congenital esophageal stenosis despite repeated balloon dilatation without methylprednisolone. However, the symptoms of dysphagia improved and did not recur after systemic steroid pulse therapy following balloon dilatation. Symptoms also resolved in all three patients with anastomotic strictures following balloon dilatation with systemic steroid pulse therapy. All six patients remained asymptomatic after 6–21 months follow-up, with no complications. Conclusion: Intravenous methylprednisolone pulse therapy following balloon dilatation is safe and effective for the treatment of esophageal stenosis and strictures in children.
内容記述タイプ Abstract
出版者
出版者 Springer
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
ISSN
収録物識別子タイプ ISSN
収録物識別子 0179-0358
書誌情報 Pediatric Surgery International

巻 32, 号 9, p. 875-879, 発行日 2016-09
著者版フラグ
値 author
URI
識別子 http://doi.org/10.1007/s00383-016-3939-5
識別子タイプ DOI
URI
識別子 http://hdl.handle.net/2237/25144
識別子タイプ HDL
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