ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "f3ae4386-2db3-4662-84ab-a4db563c00fc"}, "_deposit": {"id": "23011", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "23011"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00023011", "sets": ["1937"]}, "author_link": ["67996", "67997", "67998", "67999", "68000", "68001"], "item_10_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2016-03-25", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "6", "bibliographicPageEnd": "1132", "bibliographicPageStart": "1123", "bibliographicVolumeNumber": "57", "bibliographic_titles": [{"bibliographic_title": "Plant and Cell Physiology", "bibliographic_titleLang": "en"}]}]}, "item_10_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Plants possess disease resistance (R) proteins encoded by R genes, and each R protein recognizes a specific pathogen factor(s) for immunity. Interestingly, a remarkably high degree of polymorphisms in R genes, which are traces of past mutation events during evolution, suggest the rapid diversification of R genes. However, little is known about molecular aspects that facilitate the rapid change of R genes because of the lack of tools that enable us to monitor de novo R gene mutations efficiently in an experimentally feasible time scale, especially in living plants. Here we introduce a model assay system that enables efficient in planta detection of de novo mutation events in the Arabidopsis thaliana R gene UNI in one generation. The uni-1D mutant harbors a gain-of-function allele of the UNI gene. uni-1D heterozygous individuals originally exhibit dwarfism with abnormally short stems. However, interestingly, morphologically normal stems sometimes emerge spontaneously from the uni-1D plants, and the morphologically reverted tissues carry additional de novo mutations in the UNI gene. Strikingly, under an extreme condition, almost half of the examined population shows the reversion phenomenon. By taking advantage of this phenomenon, we demonstrate that the reversion frequency is remarkably sensitive to a variety of fluctuations in DNA stability, underlying a mutable tendency of the UNI gene. We also reveal that activities of the salicylic acid pathway and DNA damage sensor pathway are involved in the reversion phenomenon. Thus, we provide an experimentally feasible model tool to explore factors and conditions that significantly affect the R gene mutation phenomenon.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "DOI", "subitem_identifier_uri": "http://doi.org/10.1093/pcp/pcw060"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/25198"}]}, "item_10_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Oxford University Press", "subitem_publisher_language": "en"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1093/pcp/pcw060", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "This is a pre-copyedited, author-produced version of an article accepted for publication in [Plant \u0026 Cell Physiology] following peer review. The version of record [Plant and Cell Physiology. v.57, n.6, 2016, p.1123-1132] is available online at: http://doi.org/10.1093/pcp/pcw060.", "subitem_rights_language": "en"}]}, "item_10_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0032-0781", "subitem_source_identifier_type": "PISSN"}]}, "item_1615787544753": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Ogawa, Tomohiko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "67996", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mori, Akiko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "67997", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Igari, Kadunari", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "67998", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Morita, Terao  Miyo", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "67999", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tasaka, Masao", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "68000", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Uchida, Naoyuki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "68001", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-03-25"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Ogawa_et_al.pdf", "filesize": [{"value": "1.5 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 1500000.0, "url": {"label": "Ogawa_et_al.pdf ファイル公開:2017/03/25", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/23011/files/Ogawa_et_al.pdf"}, "version_id": "67226e48-3af7-4d3e-acd5-9c613755a2da"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Arabidopsis thaliana", "subitem_subject_scheme": "Other"}, {"subitem_subject": "DNA damage sensor pathway", "subitem_subject_scheme": "Other"}, {"subitem_subject": "R gene", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Mutation", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Salicylic acid pathway", "subitem_subject_scheme": "Other"}, {"subitem_subject": "UNI", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Efficient In Planta Detection and Dissection of De Novo Mutation Events in the Arabidopsis thaliana Disease Resistance Gene UNI", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Efficient In Planta Detection and Dissection of De Novo Mutation Events in the Arabidopsis thaliana Disease Resistance Gene UNI", "subitem_title_language": "en"}]}, "item_type_id": "10", "owner": "1", "path": ["1937"], "permalink_uri": "http://hdl.handle.net/2237/25198", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2016-12-14"}, "publish_date": "2016-12-14", "publish_status": "0", "recid": "23011", "relation": {}, "relation_version_is_last": true, "title": ["Efficient In Planta Detection and Dissection of De Novo Mutation Events in the Arabidopsis thaliana Disease Resistance Gene UNI"], "weko_shared_id": -1}
  1. I300 トランスフォーマティブ生命分子研究所
  2. I300a 雑誌掲載論文
  3. 学術雑誌

Efficient In Planta Detection and Dissection of De Novo Mutation Events in the Arabidopsis thaliana Disease Resistance Gene UNI

http://hdl.handle.net/2237/25198
http://hdl.handle.net/2237/25198
7448b5d7-ad27-483b-ad68-07e09a45b8af
名前 / ファイル ライセンス アクション
Ogawa_et_al.pdf Ogawa_et_al.pdf ファイル公開:2017/03/25 (1.5 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2016-12-14
タイトル
タイトル Efficient In Planta Detection and Dissection of De Novo Mutation Events in the Arabidopsis thaliana Disease Resistance Gene UNI
言語 en
著者 Ogawa, Tomohiko

× Ogawa, Tomohiko

WEKO 67996

en Ogawa, Tomohiko

Search repository
Mori, Akiko

× Mori, Akiko

WEKO 67997

en Mori, Akiko

Search repository
Igari, Kadunari

× Igari, Kadunari

WEKO 67998

en Igari, Kadunari

Search repository
Morita, Terao Miyo

× Morita, Terao Miyo

WEKO 67999

en Morita, Terao Miyo

Search repository
Tasaka, Masao

× Tasaka, Masao

WEKO 68000

en Tasaka, Masao

Search repository
Uchida, Naoyuki

× Uchida, Naoyuki

WEKO 68001

en Uchida, Naoyuki

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 This is a pre-copyedited, author-produced version of an article accepted for publication in [Plant & Cell Physiology] following peer review. The version of record [Plant and Cell Physiology. v.57, n.6, 2016, p.1123-1132] is available online at: http://doi.org/10.1093/pcp/pcw060.
キーワード
主題Scheme Other
主題 Arabidopsis thaliana
キーワード
主題Scheme Other
主題 DNA damage sensor pathway
キーワード
主題Scheme Other
主題 R gene
キーワード
主題Scheme Other
主題 Mutation
キーワード
主題Scheme Other
主題 Salicylic acid pathway
キーワード
主題Scheme Other
主題 UNI
抄録
内容記述 Plants possess disease resistance (R) proteins encoded by R genes, and each R protein recognizes a specific pathogen factor(s) for immunity. Interestingly, a remarkably high degree of polymorphisms in R genes, which are traces of past mutation events during evolution, suggest the rapid diversification of R genes. However, little is known about molecular aspects that facilitate the rapid change of R genes because of the lack of tools that enable us to monitor de novo R gene mutations efficiently in an experimentally feasible time scale, especially in living plants. Here we introduce a model assay system that enables efficient in planta detection of de novo mutation events in the Arabidopsis thaliana R gene UNI in one generation. The uni-1D mutant harbors a gain-of-function allele of the UNI gene. uni-1D heterozygous individuals originally exhibit dwarfism with abnormally short stems. However, interestingly, morphologically normal stems sometimes emerge spontaneously from the uni-1D plants, and the morphologically reverted tissues carry additional de novo mutations in the UNI gene. Strikingly, under an extreme condition, almost half of the examined population shows the reversion phenomenon. By taking advantage of this phenomenon, we demonstrate that the reversion frequency is remarkably sensitive to a variety of fluctuations in DNA stability, underlying a mutable tendency of the UNI gene. We also reveal that activities of the salicylic acid pathway and DNA damage sensor pathway are involved in the reversion phenomenon. Thus, we provide an experimentally feasible model tool to explore factors and conditions that significantly affect the R gene mutation phenomenon.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 Oxford University Press
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1093/pcp/pcw060
ISSN
収録物識別子タイプ PISSN
収録物識別子 0032-0781
書誌情報 en : Plant and Cell Physiology

巻 57, 号 6, p. 1123-1132, 発行日 2016-03-25
著者版フラグ
値 author
URI
識別子 http://doi.org/10.1093/pcp/pcw060
識別子タイプ DOI
URI
識別子 http://hdl.handle.net/2237/25198
識別子タイプ HDL
戻る
0
views
See details
Views

Versions

Ver.1 2021-03-01 14:44:11.667289
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3