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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Contrast MRI Findings for Spinal Schwannoma as Predictors of Tumor Proliferation and Motor Status

http://hdl.handle.net/2237/25632
http://hdl.handle.net/2237/25632
17668d9d-c80c-49d6-9259-fd70c18a7bb7
名前 / ファイル ライセンス アクション
Contrast_MRI_findings.pdf Contrast_MRI_findings.pdf ファイル公開:2018/02/01 (2.3 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2017-02-27
タイトル
タイトル Contrast MRI Findings for Spinal Schwannoma as Predictors of Tumor Proliferation and Motor Status
言語 en
著者 Kobayashi, Kazuyoshi

× Kobayashi, Kazuyoshi

WEKO 69570

en Kobayashi, Kazuyoshi

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Imagama, Shiro

× Imagama, Shiro

WEKO 69571

en Imagama, Shiro

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Ando, Kei

× Ando, Kei

WEKO 69572

en Ando, Kei

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Hida, Tetsuro

× Hida, Tetsuro

WEKO 69573

en Hida, Tetsuro

Search repository
Ito, Kenyu

× Ito, Kenyu

WEKO 69574

en Ito, Kenyu

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Tsushima, Mikito

× Tsushima, Mikito

WEKO 69575

en Tsushima, Mikito

Search repository
Ishikawa, Yoshimoto

× Ishikawa, Yoshimoto

WEKO 69576

en Ishikawa, Yoshimoto

Search repository
Matsumoto, Akiyuki

× Matsumoto, Akiyuki

WEKO 69577

en Matsumoto, Akiyuki

Search repository
Morozumi, Masayoshi

× Morozumi, Masayoshi

WEKO 69578

en Morozumi, Masayoshi

Search repository
Tanaka, Satoshi

× Tanaka, Satoshi

WEKO 69579

en Tanaka, Satoshi

Search repository
Ishiguro, Naoki

× Ishiguro, Naoki

WEKO 69580

en Ishiguro, Naoki

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 This is a non-final version of an article published in final form in (Spine. 42(3):E150-E155, February 1, 2017.).
キーワード
主題Scheme Other
主題 Spinal schwannoma
キーワード
主題Scheme Other
主題 Contrast MRI
キーワード
主題Scheme Other
主題 Heterogeneous intensity
キーワード
主題Scheme Other
主題 MIB-1 index
キーワード
主題Scheme Other
主題 Motor status
抄録
内容記述 Study Design. Retrospective analysis. Objective. The goal of this study was to examine the relationship of the proliferation potency based on the MIB-1 index and motor status with features of T2-weighted images (T2WI) and contrast T1-weighted images (T1WI) of spinal schwannoma. Summary of Background Data. Spinal schwannomas account for 55% of spinal tumors, but the relationship of cellular proliferation with MRI findings for spinal schwannoma is unknown. Methods. The subjects were 48 patients (22 males and 26 females) with spinal schwannoma who were classified into three subgroups: iso/homo, high/rim, and hetero/hetero, based on T2WI/contrast T1WI. A retrospective analysis of tumor size and MIB-1 index was performed in the context of these MRI findings. Intraoperative findings and pre- and postoperative motor performance were also examined. Results. The average tumor size was 32.4 mm (range 10–130 mm) and the average MIB-1 index was 3.8% (range 1–12). In the three subgroups, there were no significant differences in sex, age, duration of disease, tumor lesion, and dumbbell type. In the hetero/hetero group, the tumor size was significantly greater and the MIB-1 index was significantly higher (both P < 0.05), than the other two groups. The tumor adherence rate was significantly higher for hetero tumors (P < 0.05) and preoperative paralysis was more common in cases with tumor adhesion. The rate of paralysis improvement at 1 month was significantly lower for hetero tumors, but all cases had improved at 6 months. Conclusion. Contrast T1WI MRI was useful for prediction of the proliferative activity and growth of spinal schwannomas, which are associated with increased tumor size and adhesion. A heterogeneous pattern on contrast T1WI indicated an increase in size and adhesion of the tumor. This pattern reflected the preoperative motor status and postoperative motor recovery.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 Wolters Kluwer Health
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1097/BRS.0000000000001732
ISSN
収録物識別子タイプ PISSN
収録物識別子 0362-2436
書誌情報 en : SPINE

巻 42, 号 3, p. E150-E155, 発行日 2017-02
著者版フラグ
値 author
URI
識別子 http://doi.org/10.1097/BRS.0000000000001732
識別子タイプ DOI
URI
識別子 http://hdl.handle.net/2237/25632
識別子タイプ HDL
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