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The objective of this study was to investigate a case series of hyperamylasemia and pancreatitis following posterior spinal surgery. Methods: The serum amylase level was measured following posterior spinal surgery in the prone position. Patients were divided into groups with a normal serum amylase level (0–125 IU/L) and with hyperamylasemia (\u003e125 IU/L), based on the upper limit of normal of 125 IU/L in our institution. Relationships among preoperative factors, perioperative factors, and the serum amylase level were investigated. Results: Hyperamylasemia (serum amylase \u003e125 IU/L) following posterior spinal surgery was found in 92 cases (35 %). Among perioperative factors, intraoperative estimated blood loss (EBL) and operating time were significantly higher in patients with high serum amylase than in patients with normal serum amylase (P \u003c 0.01). In a multivariate regression model, intraoperative EBL (OR 1.001, 95 % CI 1.000–1.002; P = 0.001) and operation time (OR 1.006, 95 % CI 1.003–1.009; P = 0.006) were significantly associated with postoperative pancreatitis. Serum amylase levels of ≥5 times the upper limit of normal were found in six cases. Five of these cases were asymptomatic and one was caused by severe pancreatitis. Conclusions: In our case series, intraoperative blood loss caused a rise in the serum amylase level following posterior spinal surgery. Thus, this level should be carefully monitored after spinal surgery with significant blood loss. 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Hyperamylasemia and pancreatitis following posterior spinal surgery
http://hdl.handle.net/2237/25634
http://hdl.handle.net/2237/256342e06fc58-200c-4113-867a-95c1c3fdc6be
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-02-27 | |||||
タイトル | ||||||
タイトル | Hyperamylasemia and pancreatitis following posterior spinal surgery | |||||
言語 | en | |||||
著者 |
Kobayashi, Kazuyoshi
× Kobayashi, Kazuyoshi× Imagama, Shiro× Ito, Zenya× Ando, Kei× Shinjo, Ryuichi× Yagi, Hideki× Hida, Tetsuro× Ito, Kenyu× Ishikawa, Yoshimoto× Ishiguro, Naoki |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | The final publication is available at Springer via http://doi.org/10.1007/s00776-015-0754-0 | |||||
抄録 | ||||||
内容記述 | Background: Postoperative pancreatitis has primarily been reported as a complication of abdominal surgery, but there are some case reports of postoperative pancreatitis after spinal surgery. The objective of this study was to investigate a case series of hyperamylasemia and pancreatitis following posterior spinal surgery. Methods: The serum amylase level was measured following posterior spinal surgery in the prone position. Patients were divided into groups with a normal serum amylase level (0–125 IU/L) and with hyperamylasemia (>125 IU/L), based on the upper limit of normal of 125 IU/L in our institution. Relationships among preoperative factors, perioperative factors, and the serum amylase level were investigated. Results: Hyperamylasemia (serum amylase >125 IU/L) following posterior spinal surgery was found in 92 cases (35 %). Among perioperative factors, intraoperative estimated blood loss (EBL) and operating time were significantly higher in patients with high serum amylase than in patients with normal serum amylase (P < 0.01). In a multivariate regression model, intraoperative EBL (OR 1.001, 95 % CI 1.000–1.002; P = 0.001) and operation time (OR 1.006, 95 % CI 1.003–1.009; P = 0.006) were significantly associated with postoperative pancreatitis. Serum amylase levels of ≥5 times the upper limit of normal were found in six cases. Five of these cases were asymptomatic and one was caused by severe pancreatitis. Conclusions: In our case series, intraoperative blood loss caused a rise in the serum amylase level following posterior spinal surgery. Thus, this level should be carefully monitored after spinal surgery with significant blood loss. Clinical symptoms of pancreatitis, such as abdominal pain and vomiting, should also be monitored following spinal surgery. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Springer | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプresource | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1007/s00776-015-0754-0 | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0949-2658 | |||||
書誌情報 |
en : Journal of Orthopaedic Science 巻 20, 号 6, p. 967-972, 発行日 2015-11 |
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著者版フラグ | ||||||
値 | author | |||||
URI | ||||||
識別子 | http://doi.org/10.1007/s00776-015-0754-0 | |||||
識別子タイプ | DOI | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/25634 | |||||
識別子タイプ | HDL |