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Articulation Features of Parkinson’s Disease Patients with Subthalamic Nucleus Deep Brain Stimulation
http://hdl.handle.net/2237/26007
http://hdl.handle.net/2237/2600780b9e2b9-fa4d-45c4-8310-427cce67fe4c
| 名前 / ファイル | ライセンス | アクション |
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Articulation_features_of_Parkinson.pdf (461.2 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2017-04-18 | |||||
| タイトル | ||||||
| タイトル | Articulation Features of Parkinson’s Disease Patients with Subthalamic Nucleus Deep Brain Stimulation | |||||
| 言語 | en | |||||
| 著者 |
Tanaka, Yasuhiro
× Tanaka, Yasuhiro× Tsuboi, Takashi× Watanabe, Hirohisa× Kajita, Yasukazu× Nakatsubo, Daisuke× Fujimoto, Yasushi× Ohdake, Reiko× Ito, Mizuki× Atsuta, Naoki× Yamamoto, Masahiko× Wakabayashi, Toshihiko× Katsuno, Masahisa× Sobue, Gen |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background: Voice and speech disorders are one of the most important issues after subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson’s disease (PD) patients. However, articulation features in this patient population remain unclear. Objective: We studied the articulation features of PD patients with STN-DBS. Methods: Participants were 56 PD patients treated with STN-DBS (STN-DBS group) and 41 patients treated only with medical therapy (medical-therapy-alone group). Articulation function was evaluated with acoustic and auditory-perceptual analyses. The vowel space area (VSA) was calculated using the formant frequency data of three vowels (/a/, /i/, and /u/) from sustained phonation task. The VSA reportedly reflects the distance of mouth/jaw and tongue movements during speech and phonation. Correlations between acoustic and auditory-perceptual measurements were also assessed. Results: The VSA did not significantly differ between the medical-therapy-alone group and the STN-DBS group in the off-stimulation condition. In the STN-DBS group, the VSA was larger in the on-stimulation condition than in the off-stimulation condition. However, individual analysis showed the VSA changes after stopping stimulation were heterogeneous. In total, 89.8% of the STN-DBS group showed a large VSA size in the on- than in the off-stimulation condition. In contrast, the VSA of the remaining patients in that group was smaller in the on- than the off-stimulation condition. Conclusions: STN-DBS may resolve hypokinesia of the articulation structures, including the mouth/jaw and tongue, and improve maximal vowel articulation. However, in the on-stimulation condition, the VSA was not significantly correlated with speech intelligibility. This may be because STN-DBS potentially affects other speech processes such as voice and/or respiratory process. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | IOS Press | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 出版タイプ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.3233/JPD-160838 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 1877-7171 | |||||
| 書誌情報 |
en : Journal of Parkinson's Disease 巻 6, 号 4, p. 811-819, 発行日 2016-10-19 |
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| 値 | author | |||||
| URI | ||||||
| 識別子 | http://doi.org/10.3233/JPD-160838 | |||||
| 識別子タイプ | DOI | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/26007 | |||||
| 識別子タイプ | HDL | |||||
