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Lower body mass index is associated with orthostatic hypotension in Parkinson's disease
http://hdl.handle.net/2237/26271
http://hdl.handle.net/2237/26271a5a382bf-5e76-4d56-bae5-a6b5470ecb8e
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
Nakamura_161018.pdf ファイル公開：2018/01/15 (520.4 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-05-10 | |||||
| タイトル | ||||||
| タイトル | Lower body mass index is associated with orthostatic hypotension in Parkinson's disease | |||||
| 言語 | en | |||||
| 著者 |
Nakamura, Tomohiko
× Nakamura, Tomohiko× Suzuki, Masashi× Ueda, Miki× Hirayama, Masaaki× Katsuno, Masahisa |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 権利 | ||||||
| 言語 | en | |||||
| 権利情報 | © 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Parkinson's disease | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Orthostatic hypotension | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Body mass index | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Sympathetic nervous system | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Autonomic dysfunction | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Introduction: Lower body mass index (BMI) is associated with orthostatic hypotension (OH) in the general population, especially in the elderly; however, no studies have addressed this issue in Parkinson's disease (PD). Methods: We investigated the results of the head-up tilt test and BMI of patients with PD, and evaluated whether BMI is related to orthostatic systolic blood pressure (SBP) change during the head-up tilt test. PD patients were divided into male and female groups, and further divided into middle-aged (age < 65 years) and elderly (age ≥ 65 years) subgroups in each sex. Results: OH was observed in 13 of 64 male and 12 of 75 female patients with PD. BMI was lower in patients with OH than in those without, in both men and women. In the elderly group, a significant correlation between BMI and orthostatic SBP change was found (men, r = 0.47, p = 0.006; women, r = 0.43, p = 0.005), and a BMI below mean − 0.5 standard deviation increased OH odds (men: BMI < 20.5; odds ratio, 6.79; 95% CI, 1.06–43.36; women: BMI < 18.5; odds ratio, 5.11; 95% CI, 1.05–24.96). Conclusion: Lower BMI is a predisposing factor of OH in elderly patients with PD. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Elsevier | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 出版タイプ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1016/j.jns.2016.11.027 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0022-510X | |||||
| 書誌情報 |
en : Journal of the Neurological Sciences 巻 372, p. 14-18, 発行日 2017-01-15 |
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| 著者版フラグ | ||||||
| 値 | author | |||||
| URI | ||||||
| 識別子 | https://doi.org/10.1016/j.jns.2016.11.027 | |||||
| 識別子タイプ | DOI | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/26271 | |||||
| 識別子タイプ | HDL | |||||
