{"_buckets": {"deposit": "5ade2927-6c15-44f4-8390-750add6a1139"}, "_deposit": {"id": "24335", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "24335"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00024335"}, "item_9_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2017-05", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "177", "bibliographicPageStart": "167", "bibliographicVolumeNumber": "79", "bibliographic_titles": [{"bibliographic_title": "Nagoya Journal of Medical Science"}]}]}, "item_9_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Arsenic created a serious public health problem in Bangladesh due to its presence in groundwater and dissemination of the toxic effects to millions of people. The scarcity of the treatment options to manage this affected population has made the situation much worse. To find a promising treatment option, this study was undertaken to examine the ameliorating roles of Syzygium cumini leaf extract (SLE) against arsenicinduced toxic effects in mice. Swiss albino mice were divided into four groups where \u2018control\u2019 group received pure water + normal feed, \u2018arsenic (As)\u2019 group received sodium arsenite (NaAsO2)-containing water (10 \u03bcg/g body weight/day) + normal feed, \u2018As+SLE\u2019 group received NaAsO2-containing water + feed supplemented with SLE (50 \u03bcg/g body weight/day) and finally the \u2018SLE\u2019 group received pure water + feed supplemented with SLE. A gradual increase in body weight gain was observed in control mice; however, the body weight gain in As-exposed mice was decreased. This decrease in body weight gain was prevented in As+SLE group mice that received SLE supplemented feed. Arsenic showed a secondary effect by causing enlargement of spleen, kidney and liver of \u2018As\u2019 group mice and this enlargement of the organs was minimized with SLE supplementation. In addition, SLE abrogated arsenic-mediated elevation of serum alkaline phosphatase (ALP), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), uric acid and glucose. These results, therefore, suggest that SLE might have future therapeutic value for preventing or reducing arsenic-induced toxic effects.", "subitem_description_type": "Abstract"}]}, "item_9_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "URI", "subitem_identifier_uri": "http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/792.html"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/26539"}]}, "item_9_identifier_registration": {"attribute_name": "ID\u767b\u9332", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.18999/nagjms.79.2.167", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Nagoya University Graduate School of Medicine, School of Medicine"}]}, "item_9_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_9_source_id_7": {"attribute_name": "ISSN\uff08print\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "0027-7622", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Milan, Barai"}], "nameIdentifiers": [{"nameIdentifier": "71995", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nazmul, Ahsan"}], "nameIdentifiers": [{"nameIdentifier": "71996", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nilanjana, Paul"}], "nameIdentifiers": [{"nameIdentifier": "71997", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Khaled, Hossain"}], "nameIdentifiers": [{"nameIdentifier": "71998", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mohammad, Abdur Rashid"}], "nameIdentifiers": [{"nameIdentifier": "71999", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kato, Masashi"}], "nameIdentifiers": [{"nameIdentifier": "72000", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ohgami, Nobutaka"}], "nameIdentifiers": [{"nameIdentifier": "72001", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Anwarul, Azim Akhand"}], "nameIdentifiers": [{"nameIdentifier": "72002", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-22"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "15_MilanBarai.pdf", "filesize": [{"value": "998.7 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 998700.0, "url": {"label": "15_MilanBarai.pdf", "url": "https://nagoya.repo.nii.ac.jp/record/24335/files/15_MilanBarai.pdf"}, "version_id": "293cde14-9abe-426f-a653-5328210ff3bc"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Sodium arsenite", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Mice", "subitem_subject_scheme": "Other"}, {"subitem_subject": "S. cumini leaf extract", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Serum parameters", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Organ enlargement", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Amelioration of arsenic-induced toxic effects in mice by dietary supplementation of Syzygium cumini leaf extract", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Amelioration of arsenic-induced toxic effects in mice by dietary supplementation of Syzygium cumini leaf extract"}]}, "item_type_id": "9", "owner": "1", "path": ["499/508/509/2025"], "permalink_uri": "https://doi.org/10.18999/nagjms.79.2.167", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2017-06-01"}, "publish_date": "2017-06-01", "publish_status": "0", "recid": "24335", "relation": {}, "relation_version_is_last": true, "title": ["Amelioration of arsenic-induced toxic effects in mice by dietary supplementation of Syzygium cumini leaf extract"], "weko_shared_id": null}