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A case of API2-MALT1-positive gastric MALT lymphoma with concomitant diffuse large B-cell lymphoma
https://doi.org/10.18999/nagjms.79.2.251
https://doi.org/10.18999/nagjms.79.2.251604d84a0-48aa-4c28-8d21-c9788f799ec2
名前 / ファイル | ライセンス | アクション |
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41_AkashiFujita.pdf (2.9 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2017-06-01 | |||||
タイトル | ||||||
タイトル | A case of API2-MALT1-positive gastric MALT lymphoma with concomitant diffuse large B-cell lymphoma | |||||
言語 | en | |||||
著者 |
Fujita, Akashi
× Fujita, Akashi× Tajika, Masahiro× Tanaka, Tsutomu× Ishihara, Makoto× Hirayama, Yutaka× Mizuno, Nobumasa× Hara, Kazuo× Hijioka, Susumu× Imaoka, Hiroshi× Yoshida, Tsukasa× Okuno, Nozomi× Hieda, Nobuhiro× Hirayama, Takashi× Shibuya, Hitoshi× Kondo, Hisashi× Suzuki, Hirotaka× Toriyama, Kazuhiro× Yatabe, Yasushi× Yamao, Kenji× Niwa, Yasumasa |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報Resource | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
権利情報 | Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | MALT lymphoma | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Second malignancy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | API2-MALT1 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | DLBCL | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | API2-MALT1 translocation-positive gastric marginal zone lymphomas of mucosa-associated lymphoid tissue (MALT) lymphoma is thought to transform to diffuse large B-cell lymphoma (DLBCL) rarely. A 69-year-old man presented with epigastralgia. Esophagogastroduodenoscopy showed multiple ulcerations in the stomach. Endoscopic biopsies revealed MALT lymphoma, with Helicobacter pylori infection. The patient underwent eradication therapy with no improvement, and was thereafter followed without additional therapy at his request. Twelve years after initial diagnosis, follow-up computed tomography (CT) showed multiple nodules in bilateral lungs, and a needle biopsy revealed MALT lymphoma, the same as in the stomach and API2-MALT1 translocation was found. Because he again refused additional therapy, follow-up was continued. 15 years after initial diagnosis, CT showed lymphadenopathy at the splenic hilum. At first we suspected disease progression of gastric MALT lymphoma, however a needle biopsy revealed DLBCL without API2-MALT1. Thus, the tumor at the splenic hilum was finally diagnosed as a de novo DLBCL as a second malignancy. Although treatment with rituximab given his age and his wishes was attempted, he died of DLBCL 15 years after the initial diagnosis. We experienced an API2-MALT1-positive gastric MALT lymphoma with concomitant DLBCL, not transformed to DLBCL over a 15-year clinical course. | |||||
言語 | en | |||||
出版者 | ||||||
出版者 | Nagoya University Graduate School of Medicine, School of Medicine | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.79.2.251 | |||||
ID登録タイプ | JaLC | |||||
関連情報 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/792.html | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
en : Nagoya Journal of Medical Science 巻 79, 号 2, p. 251-257, 発行日 2017-05 |
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著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/26550 | |||||
識別子タイプ | HDL |