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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 79(2)

A case of API2-MALT1-positive gastric MALT lymphoma with concomitant diffuse large B-cell lymphoma

https://doi.org/10.18999/nagjms.79.2.251
https://doi.org/10.18999/nagjms.79.2.251
604d84a0-48aa-4c28-8d21-c9788f799ec2
名前 / ファイル ライセンス アクション
41_AkashiFujita.pdf 41_AkashiFujita.pdf (2.9 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2017-06-01
タイトル
タイトル A case of API2-MALT1-positive gastric MALT lymphoma with concomitant diffuse large B-cell lymphoma
著者 Fujita, Akashi

× Fujita, Akashi

WEKO 72059

Fujita, Akashi

Search repository
Tajika, Masahiro

× Tajika, Masahiro

WEKO 72060

Tajika, Masahiro

Search repository
Tanaka, Tsutomu

× Tanaka, Tsutomu

WEKO 72061

Tanaka, Tsutomu

Search repository
Ishihara, Makoto

× Ishihara, Makoto

WEKO 72062

Ishihara, Makoto

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Hirayama, Yutaka

× Hirayama, Yutaka

WEKO 72063

Hirayama, Yutaka

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Mizuno, Nobumasa

× Mizuno, Nobumasa

WEKO 72064

Mizuno, Nobumasa

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Hara, Kazuo

× Hara, Kazuo

WEKO 72065

Hara, Kazuo

Search repository
Hijioka, Susumu

× Hijioka, Susumu

WEKO 72066

Hijioka, Susumu

Search repository
Imaoka, Hiroshi

× Imaoka, Hiroshi

WEKO 72067

Imaoka, Hiroshi

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Yoshida, Tsukasa

× Yoshida, Tsukasa

WEKO 72068

Yoshida, Tsukasa

Search repository
Okuno, Nozomi

× Okuno, Nozomi

WEKO 72069

Okuno, Nozomi

Search repository
Hieda, Nobuhiro

× Hieda, Nobuhiro

WEKO 72070

Hieda, Nobuhiro

Search repository
Hirayama, Takashi

× Hirayama, Takashi

WEKO 72071

Hirayama, Takashi

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Shibuya, Hitoshi

× Shibuya, Hitoshi

WEKO 72072

Shibuya, Hitoshi

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Kondo, Hisashi

× Kondo, Hisashi

WEKO 72073

Kondo, Hisashi

Search repository
Suzuki, Hirotaka

× Suzuki, Hirotaka

WEKO 72074

Suzuki, Hirotaka

Search repository
Toriyama, Kazuhiro

× Toriyama, Kazuhiro

WEKO 72075

Toriyama, Kazuhiro

Search repository
Yatabe, Yasushi

× Yatabe, Yasushi

WEKO 72076

Yatabe, Yasushi

Search repository
Yamao, Kenji

× Yamao, Kenji

WEKO 72077

Yamao, Kenji

Search repository
Niwa, Yasumasa

× Niwa, Yasumasa

WEKO 72078

Niwa, Yasumasa

Search repository
キーワード
主題Scheme Other
主題 MALT lymphoma
キーワード
主題Scheme Other
主題 Second malignancy
キーワード
主題Scheme Other
主題 API2-MALT1
キーワード
主題Scheme Other
主題 DLBCL
抄録
内容記述 API2-MALT1 translocation-positive gastric marginal zone lymphomas of mucosa-associated lymphoid tissue (MALT) lymphoma is thought to transform to diffuse large B-cell lymphoma (DLBCL) rarely. A 69-year-old man presented with epigastralgia. Esophagogastroduodenoscopy showed multiple ulcerations in the stomach. Endoscopic biopsies revealed MALT lymphoma, with Helicobacter pylori infection. The patient underwent eradication therapy with no improvement, and was thereafter followed without additional therapy at his request. Twelve years after initial diagnosis, follow-up computed tomography (CT) showed multiple nodules in bilateral lungs, and a needle biopsy revealed MALT lymphoma, the same as in the stomach and API2-MALT1 translocation was found. Because he again refused additional therapy, follow-up was continued. 15 years after initial diagnosis, CT showed lymphadenopathy at the splenic hilum. At first we suspected disease progression of gastric MALT lymphoma, however a needle biopsy revealed DLBCL without API2-MALT1. Thus, the tumor at the splenic hilum was finally diagnosed as a de novo DLBCL as a second malignancy. Although treatment with rituximab given his age and his wishes was attempted, he died of DLBCL 15 years after the initial diagnosis. We experienced an API2-MALT1-positive gastric MALT lymphoma with concomitant DLBCL, not transformed to DLBCL over a 15-year clinical course.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.79.2.251
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 79, 号 2, p. 251-257, 発行日 2017-05
著者版フラグ
値 publisher
URI
識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/792.html
識別子タイプ URI
URI
識別子 http://hdl.handle.net/2237/26550
識別子タイプ HDL
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