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  1. C100 医学部/医学系研究科
  2. C100b 刊行物
  3. Nagoya journal of medical science
  4. 79(2)

A case of API2-MALT1-positive gastric MALT lymphoma with concomitant diffuse large B-cell lymphoma

https://doi.org/10.18999/nagjms.79.2.251
https://doi.org/10.18999/nagjms.79.2.251
604d84a0-48aa-4c28-8d21-c9788f799ec2
名前 / ファイル ライセンス アクション
41_AkashiFujita.pdf 41_AkashiFujita.pdf (2.9 MB)
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アイテムタイプ 紀要論文 / Departmental Bulletin Paper(1)
公開日 2017-06-01
タイトル
タイトル A case of API2-MALT1-positive gastric MALT lymphoma with concomitant diffuse large B-cell lymphoma
言語 en
著者 Fujita, Akashi

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Tajika, Masahiro

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Tanaka, Tsutomu

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Ishihara, Makoto

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Hirayama, Yutaka

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Mizuno, Nobumasa

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Hara, Kazuo

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Hijioka, Susumu

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Imaoka, Hiroshi

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Yoshida, Tsukasa

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Okuno, Nozomi

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Hieda, Nobuhiro

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Hirayama, Takashi

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Shibuya, Hitoshi

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Kondo, Hisashi

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Suzuki, Hirotaka

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Toriyama, Kazuhiro

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Yatabe, Yasushi

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Yamao, Kenji

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Niwa, Yasumasa

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
権利情報Resource http://creativecommons.org/licenses/by-nc-nd/4.0/
権利情報 Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
言語 en
キーワード
主題Scheme Other
主題 MALT lymphoma
キーワード
主題Scheme Other
主題 Second malignancy
キーワード
主題Scheme Other
主題 API2-MALT1
キーワード
主題Scheme Other
主題 DLBCL
抄録
内容記述タイプ Abstract
内容記述 API2-MALT1 translocation-positive gastric marginal zone lymphomas of mucosa-associated lymphoid tissue (MALT) lymphoma is thought to transform to diffuse large B-cell lymphoma (DLBCL) rarely. A 69-year-old man presented with epigastralgia. Esophagogastroduodenoscopy showed multiple ulcerations in the stomach. Endoscopic biopsies revealed MALT lymphoma, with Helicobacter pylori infection. The patient underwent eradication therapy with no improvement, and was thereafter followed without additional therapy at his request. Twelve years after initial diagnosis, follow-up computed tomography (CT) showed multiple nodules in bilateral lungs, and a needle biopsy revealed MALT lymphoma, the same as in the stomach and API2-MALT1 translocation was found. Because he again refused additional therapy, follow-up was continued. 15 years after initial diagnosis, CT showed lymphadenopathy at the splenic hilum. At first we suspected disease progression of gastric MALT lymphoma, however a needle biopsy revealed DLBCL without API2-MALT1. Thus, the tumor at the splenic hilum was finally diagnosed as a de novo DLBCL as a second malignancy. Although treatment with rituximab given his age and his wishes was attempted, he died of DLBCL 15 years after the initial diagnosis. We experienced an API2-MALT1-positive gastric MALT lymphoma with concomitant DLBCL, not transformed to DLBCL over a 15-year clinical course.
言語 en
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語 en
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/nagjms.79.2.251
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/792.html
ISSN(print)
収録物識別子タイプ PISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ EISSN
収録物識別子 2186-3326
書誌情報 en : Nagoya Journal of Medical Science

巻 79, 号 2, p. 251-257, 発行日 2017-05
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/26550
識別子タイプ HDL
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