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Responsiveness to bronchodilator procaterol in COPD as assessed by forced oscillation technique
http://hdl.handle.net/2237/26874
http://hdl.handle.net/2237/268749775144f-4255-472c-8ce2-7718d29b14f3
名前 / ファイル | ライセンス | アクション |
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RESPNB_2017_Ito_for_NU_Library_08-02-2017.pdf ファイル公開:2018/06/01 (894.6 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-08-03 | |||||
タイトル | ||||||
タイトル | Responsiveness to bronchodilator procaterol in COPD as assessed by forced oscillation technique | |||||
言語 | en | |||||
著者 |
Ito, Satoru
× Ito, Satoru× Uchida, Akemi× Isobe, Yoshitaka× Hasegawa, Yoshinori |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | © 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Airway | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Airway smooth muscle | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Forced oscillation technique | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Impedance | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Bronchodilator | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Procaterol | |||||
抄録 | ||||||
内容記述 | The aim of this retrospective study was to assess responses to a bronchodilator by forced oscillation technique (FOT) and to relate the results of respiratory impedance (Zrs) to spirometric parameters in patients with chronic obstructive pulmonary disease (COPD). Zrs was measured as a function of frequency from 4 to 36 Hz before and after inhalation of procaterol, a short-acting β2-agonist (n = 60). Respiratory resistance (Rrs) and reactance (Xrs) were significantly frequency-dependent, and inspiratory and expiratory phases were different both before and after procaterol inhalation. The Rrs at 4 Hz and Xrs at 4–20 Hz during a whole breath were significantly improved after procaterol inhalation. The response to procaterol inhalation varied among patients, and changes in Xrs at 4 Hz significantly correlated with% change in forced expiratory volume in one second and changes in forced vital capacity. Taken together, Zrs, and specifically Xrs parameters, are sensitive to acute physiological responses to a bronchodilator in COPD. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Elsevier | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプresource | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.resp.2017.02.012 | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 1569-9048 | |||||
書誌情報 |
en : Respiratory Physiology & Neurobiology 巻 240, p. 41-47, 発行日 2017-06 |
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著者版フラグ | ||||||
値 | author | |||||
URI | ||||||
識別子 | https://doi.org/10.1016/j.resp.2017.02.012 | |||||
識別子タイプ | DOI | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/26874 | |||||
識別子タイプ | HDL |