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Responsiveness to bronchodilator procaterol in COPD as assessed by forced oscillation technique
http://hdl.handle.net/2237/26874
http://hdl.handle.net/2237/268749775144f-4255-472c-8ce2-7718d29b14f3
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
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| アイテムタイプ | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-08-03 | |||||
| タイトル | ||||||
| タイトル | Responsiveness to bronchodilator procaterol in COPD as assessed by forced oscillation technique | |||||
| 言語 | en | |||||
| 著者 |
Ito, Satoru
× Ito, Satoru× Uchida, Akemi× Isobe, Yoshitaka× Hasegawa, Yoshinori |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 権利 | ||||||
| 権利情報 | © 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
| 言語 | en | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Airway | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Airway smooth muscle | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Forced oscillation technique | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Impedance | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Bronchodilator | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Procaterol | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The aim of this retrospective study was to assess responses to a bronchodilator by forced oscillation technique (FOT) and to relate the results of respiratory impedance (Zrs) to spirometric parameters in patients with chronic obstructive pulmonary disease (COPD). Zrs was measured as a function of frequency from 4 to 36 Hz before and after inhalation of procaterol, a short-acting β2-agonist (n = 60). Respiratory resistance (Rrs) and reactance (Xrs) were significantly frequency-dependent, and inspiratory and expiratory phases were different both before and after procaterol inhalation. The Rrs at 4 Hz and Xrs at 4–20 Hz during a whole breath were significantly improved after procaterol inhalation. The response to procaterol inhalation varied among patients, and changes in Xrs at 4 Hz significantly correlated with% change in forced expiratory volume in one second and changes in forced vital capacity. Taken together, Zrs, and specifically Xrs parameters, are sensitive to acute physiological responses to a bronchodilator in COPD. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Elsevier | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプresource | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | journal article | |||||
| 出版タイプ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1016/j.resp.2017.02.012 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 1569-9048 | |||||
| 書誌情報 |
en : Respiratory Physiology & Neurobiology 巻 240, p. 41-47, 発行日 2017-06 |
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| 著者版フラグ | ||||||
| 値 | author | |||||
| URI | ||||||
| 識別子 | https://doi.org/10.1016/j.resp.2017.02.012 | |||||
| 識別子タイプ | DOI | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/26874 | |||||
| 識別子タイプ | HDL | |||||