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  1. D400 創薬科学研究科
  2. D400a 雑誌掲載論文
  3. 学術雑誌

Total Syntheses of Aurachins A and B

http://hdl.handle.net/2237/26937
cc34fe8a-3331-4499-8eda-4ee92af0a262
名前 / ファイル ライセンス アクション
20170411_hatsutori.pdf 20170411_hatsutori.pdf ファイル公開:2018/06/06 (721.6 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2017-09-04
タイトル
タイトル Total Syntheses of Aurachins A and B
著者 Hattori, Haruhiko

× Hattori, Haruhiko

WEKO 73363

Hattori, Haruhiko

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Yokoshima, Satoshi

× Yokoshima, Satoshi

WEKO 73364

Yokoshima, Satoshi

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Fukuyama, Tohru

× Fukuyama, Tohru

WEKO 73365

Fukuyama, Tohru

Search repository
権利
権利情報 "This is the peer reviewed version of the following article: [H. Hattori, S. Yokoshima, T. Fukuyama, Angew. Chem. Int. Ed. 2017, 56, 6980.], which has been published in final form at [http://doi.org/10.1002/anie.201702204]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving."
抄録
内容記述 Aurachins A and B are alkaloids having 3-hydroxyquinoline N-oxide cores. An efficient method for the synthesis of 3-hydroxyquinoline N-oxides was established and is amenable to the total syntheses of aurachins A and B. Alkylation of 1-(2-nitrophenyl)butan-2-one with farnesyl bromide took place selectively at the benzylic position, and subsequent treatment of the alkylated product with sodium tert-butoxide in dimethyl sulfoxide gave aurachin B. Alkylation of 1-(2-nitrophenyl)butan-2-one with an epoxy iodide derived from farnesol was used to access aurachin A.
内容記述タイプ Abstract
出版者
出版者 Wiley
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
ISSN
収録物識別子タイプ ISSN
収録物識別子 1433-7851
書誌情報 Angewandte Chemie-International Edition

巻 56, 号 24, p. 6980-6983, 発行日 2017-06-06
著者版フラグ
値 author
URI
識別子 http://doi.org/10.1002/anie.201702204
識別子タイプ DOI
URI
識別子 http://hdl.handle.net/2237/26937
識別子タイプ HDL
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