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Usefulness of the Combination of In-Hospital Poor Diuretic Response and Systemic Congestion to Predict Future Cardiac Events in Patients With Acute Decompensated Heart Failure
http://hdl.handle.net/2237/26959
http://hdl.handle.net/2237/269590307e911-0483-4093-b1c3-3fa0638df476
名前 / ファイル | ライセンス | アクション |
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Usefulness_of_the_Combination.pdf ファイル公開日:2018/06/15 (850.5 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-09-05 | |||||
タイトル | ||||||
タイトル | Usefulness of the Combination of In-Hospital Poor Diuretic Response and Systemic Congestion to Predict Future Cardiac Events in Patients With Acute Decompensated Heart Failure | |||||
言語 | en | |||||
著者 |
Soichiro, Aoki
× Soichiro, Aoki× Takahiro, Okumura× Akinori, Sawamura× Katsuhide, Kitagawa× Ryota, Morimoto× Masaki, Sakakibara× Toyoaki, Murohara |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | © 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | heart failure | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | diuretic response | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | congestion | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | prognosis | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We aimed to (1) investigate the relation between diuretic response (DR) with or without systemic congestion and prognosis and (2) explore the potential predictors of poor DR for risk stratification in patients with acute decompensated heart failure (ADHF). We enrolled 186 consecutive patients hospitalized for ADHF. The DR was defined as (body weight at discharge L body weight at admission)/40 mg furosemide or equivalent loop diuretic dose. Systemic congestion on admission was simply evaluated by the presence of leg edema or jugular venous distention. All patients were divided into 4 groups based on the median of DR (-0.50 kg/40 mg) and the status of systemic congestion; GR/C (good DR with systemic congestion, n = 66), GR/N (good DR without systemic congestion, n = 27), PR/C (poor DR with systemic congestion, n = 48); and PR/N (poor DR without systemic congestion, n = 45). The composite outcome was defined as cardiac death and rehospitalization for worsening heart failure. In survival analysis, the cardiac event-free rate in PR/C was significantly lower than that in any other groups (log-rank, p <0.001), and PR/C was an independent predictor of cardiac events (hazard ratio 2.17, p = 0.016). In conclusion, the combination of in-hospital poor DR, characterized by previous ischemic heart disease, and prehospital dose of daily loop diuretics, and systemic congestion provides a risk stratification for future cardiac events in patients with ADHF. | |||||
言語 | en | |||||
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出版者 | Elsevier | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.amjcard.2017.03.030 | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0002-9149 | |||||
書誌情報 |
en : The American Journal of Cardiology 巻 119, 号 12, p. 2010-2016, 発行日 2017-06-15 |
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著者版フラグ | ||||||
値 | author | |||||
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識別子 | http://doi.org/10.1016/j.amjcard.2017.03.030 | |||||
識別子タイプ | DOI | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/26959 | |||||
識別子タイプ | HDL |