WEKO3
アイテム
Evolutionary mechanisms that generate morphology and neural-circuit diversity of the cerebellum
http://hdl.handle.net/2237/27168
http://hdl.handle.net/2237/271683b6257a3-caae-4fe2-aec1-da461d2cf832
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
Hibi_DGD_2017.pdf ファイル公開日:2018/05/01 (1.5 MB)
|
|
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-12-12 | |||||
| タイトル | ||||||
| タイトル | Evolutionary mechanisms that generate morphology and neural-circuit diversity of the cerebellum | |||||
| 言語 | en | |||||
| 著者 |
Hibi, Masahiko
× Hibi, Masahiko× Matsuda, Koji× Takeuchi, Miki× Shimizu, Takashi× Murakami, Yasunori |
|||||
| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 権利 | ||||||
| 言語 | en | |||||
| 権利情報 | This is the peer reviewed version of the following article: [Development, Growth and Differentiation. v.59, n.4, 2017, p.228-243], which has been published in final form at [http://doi.org/10.1111/dgd.12349/]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | cerebellum | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | evolution | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | proneural gene | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Fgf | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Shh | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The cerebellum is derived from the dorsal part of the anterior-most hindbrain. The vertebrate cerebellum contains glutamatergic granule cells (GCs) and gamma-aminobutyric acid (GABA)ergic Purkinje cells (PCs). These cerebellar neurons are generated from neuronal progenitors or neural stem cells by mechanisms that are conserved among vertebrates. However, vertebrate cerebella are widely diverse with respect to their gross morphology and neural circuits. The cerebellum of cyclostomes, the basal vertebrates, has a negligible structure. Cartilaginous fishes have a cerebellum containing GCs, PCs, and deep cerebellar nuclei (DCNs), which include projection neurons. Ray-finned fish lack DCNs but have projection neurons termed eurydendroid cells (ECs) in the vicinity of the PCs. Among ray-finned fishes, the cerebellum of teleost zebrafish has a simple lobular structure, whereas that of weakly electric mormyrid fish is large and foliated. Amniotes, which include mammals, independently evolved a large, foliated cerebellum, which contains massive numbers of GCs and has functional connections with the dorsal telencephalon (neocortex). Recent studies of cyclostomes and cartilaginous fish suggest that the genetic program for cerebellum development was already encoded in the genome of ancestral vertebrates. In this review, we discuss how alterations of the genetic and cellular programs generated diversity of the cerebellum during evolution. | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Wiley | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプresource | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | journal article | |||||
| 出版タイプ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1111/dgd.12349 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0012-1592 | |||||
| 書誌情報 |
en : Development, Growth and Differentiation 巻 59, 号 4, p. 228-243, 発行日 2017-05 |
|||||
| 著者版フラグ | ||||||
| 値 | author | |||||
| URI | ||||||
| 識別子 | http://doi.org/10.1111/dgd.12349 | |||||
| 識別子タイプ | DOI | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/27168 | |||||
| 識別子タイプ | HDL | |||||
