ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "4924963a-fbf4-45bb-ac05-b48897fc4d8b"}, "_deposit": {"id": "25050", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "25050"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00025050", "sets": ["322"]}, "author_link": ["74697", "74698"], "item_10_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2017-09-22", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3", "bibliographicPageEnd": "030402(R)", "bibliographicPageStart": "030402(R)", "bibliographicVolumeNumber": "96", "bibliographic_titles": [{"bibliographic_title": "Physical Review E", "bibliographic_titleLang": "en"}]}]}, "item_10_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The loop extrusion theory assumes that protein factors, such as cohesin rings, act as molecular motors that extrude chromatin loops. However, recent single molecule experiments have shown that cohesin does not show motor activity. To predict the physical mechanism involved in loop extrusion, we here theoretically analyze the dynamics of cohesin rings on a loop, where a cohesin loader is in the middle and unloaders at the ends. Cohesin monomers bind to the loader rather frequently and cohesin dimers bind to this site only occasionally. Our theory predicts that a cohesin dimer extrudes loops by the osmotic pressure of cohesin monomers on the chromatin fiber between the two connected rings. With this mechanism, the frequency of the interactions between chromatin segments depends on the loading and unloading rates of dimers at the corresponding sites.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "DOI", "subitem_identifier_uri": "http://doi.org/10.1103/PhysRevE.96.030402"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/27259"}]}, "item_10_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "American Physical Society", "subitem_publisher_language": "en"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1103/PhysRevE.96.030402", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2017 American Physical Society", "subitem_rights_language": "en"}]}, "item_10_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_10_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "2470-0045", "subitem_source_identifier_type": "PISSN"}]}, "item_1615787544753": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Yamamoto, Tetsuya", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "74697", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Schiessel, Helmut", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "74698", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-22"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "PhysRevE.96.030402.pdf", "filesize": [{"value": "182.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 182400.0, "url": {"label": "PhysRevE.96.030402.pdf", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/25050/files/PhysRevE.96.030402.pdf"}, "version_id": "44013356-a53f-471d-99bf-d0d18bca2aaf"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Osmotic mechanism of the loop extrusion process", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Osmotic mechanism of the loop extrusion process", "subitem_title_language": "en"}]}, "item_type_id": "10", "owner": "1", "path": ["322"], "permalink_uri": "http://hdl.handle.net/2237/27259", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2018-01-10"}, "publish_date": "2018-01-10", "publish_status": "0", "recid": "25050", "relation": {}, "relation_version_is_last": true, "title": ["Osmotic mechanism of the loop extrusion process"], "weko_shared_id": -1}
  1. B200 工学部/工学研究科
  2. B200a 雑誌掲載論文
  3. 学術雑誌

Osmotic mechanism of the loop extrusion process

http://hdl.handle.net/2237/27259
http://hdl.handle.net/2237/27259
dce17a9e-aff2-45e9-b0f5-4e6ab762f770
名前 / ファイル ライセンス アクション
PhysRevE.96.030402.pdf PhysRevE.96.030402.pdf (182.4 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2018-01-10
タイトル
タイトル Osmotic mechanism of the loop extrusion process
言語 en
著者 Yamamoto, Tetsuya

× Yamamoto, Tetsuya

WEKO 74697

en Yamamoto, Tetsuya

Search repository
Schiessel, Helmut

× Schiessel, Helmut

WEKO 74698

en Schiessel, Helmut

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 © 2017 American Physical Society
抄録
内容記述 The loop extrusion theory assumes that protein factors, such as cohesin rings, act as molecular motors that extrude chromatin loops. However, recent single molecule experiments have shown that cohesin does not show motor activity. To predict the physical mechanism involved in loop extrusion, we here theoretically analyze the dynamics of cohesin rings on a loop, where a cohesin loader is in the middle and unloaders at the ends. Cohesin monomers bind to the loader rather frequently and cohesin dimers bind to this site only occasionally. Our theory predicts that a cohesin dimer extrudes loops by the osmotic pressure of cohesin monomers on the chromatin fiber between the two connected rings. With this mechanism, the frequency of the interactions between chromatin segments depends on the loading and unloading rates of dimers at the corresponding sites.
言語 en
内容記述タイプ Abstract
出版者
言語 en
出版者 American Physical Society
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1103/PhysRevE.96.030402
ISSN
収録物識別子タイプ PISSN
収録物識別子 2470-0045
書誌情報 en : Physical Review E

巻 96, 号 3, p. 030402(R)-030402(R), 発行日 2017-09-22
著者版フラグ
値 publisher
URI
識別子 http://doi.org/10.1103/PhysRevE.96.030402
識別子タイプ DOI
URI
識別子 http://hdl.handle.net/2237/27259
識別子タイプ HDL
戻る
0
views
See details
Views

Versions

Ver.1 2021-03-01 13:46:57.194980
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3