{"_buckets": {"deposit": "4924963a-fbf4-45bb-ac05-b48897fc4d8b"}, "_deposit": {"id": "25050", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "25050"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00025050", "sets": ["322"]}, "author_link": ["74697", "74698"], "item_10_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2017-09-22", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3", "bibliographicPageEnd": "030402(R)", "bibliographicPageStart": "030402(R)", "bibliographicVolumeNumber": "96", "bibliographic_titles": [{"bibliographic_title": "Physical Review E", "bibliographic_titleLang": "en"}]}]}, "item_10_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The loop extrusion theory assumes that protein factors, such as cohesin rings, act as molecular motors that extrude chromatin loops. However, recent single molecule experiments have shown that cohesin does not show motor activity. To predict the physical mechanism involved in loop extrusion, we here theoretically analyze the dynamics of cohesin rings on a loop, where a cohesin loader is in the middle and unloaders at the ends. Cohesin monomers bind to the loader rather frequently and cohesin dimers bind to this site only occasionally. Our theory predicts that a cohesin dimer extrudes loops by the osmotic pressure of cohesin monomers on the chromatin fiber between the two connected rings. With this mechanism, the frequency of the interactions between chromatin segments depends on the loading and unloading rates of dimers at the corresponding sites.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "DOI", "subitem_identifier_uri": "http://doi.org/10.1103/PhysRevE.96.030402"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/27259"}]}, "item_10_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "American Physical Society", "subitem_publisher_language": "en"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1103/PhysRevE.96.030402", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2017 American Physical Society", "subitem_rights_language": "en"}]}, "item_10_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_10_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "2470-0045", "subitem_source_identifier_type": "PISSN"}]}, "item_1615787544753": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Yamamoto, Tetsuya", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "74697", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Schiessel, Helmut", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "74698", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-22"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "PhysRevE.96.030402.pdf", "filesize": [{"value": "182.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 182400.0, "url": {"label": "PhysRevE.96.030402.pdf", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/25050/files/PhysRevE.96.030402.pdf"}, "version_id": "44013356-a53f-471d-99bf-d0d18bca2aaf"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Osmotic mechanism of the loop extrusion process", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Osmotic mechanism of the loop extrusion process", "subitem_title_language": "en"}]}, "item_type_id": "10", "owner": "1", "path": ["322"], "permalink_uri": "http://hdl.handle.net/2237/27259", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2018-01-10"}, "publish_date": "2018-01-10", "publish_status": "0", "recid": "25050", "relation": {}, "relation_version_is_last": true, "title": ["Osmotic mechanism of the loop extrusion process"], "weko_shared_id": -1}