{"_buckets": {"deposit": "b3291f4c-f5e1-421b-a485-2ce0cf7fbecc"}, "_deposit": {"id": "25141", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "25141"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00025141", "sets": ["501"]}, "author_link": ["75038", "75039", "75040", "75041", "75042"], "item_10_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2017-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "12", "bibliographicPageEnd": "e85", "bibliographicPageStart": "e75", "bibliographicVolumeNumber": "17", "bibliographic_titles": [{"bibliographic_title": "Clinical Lymphoma Myeloma and Leukemia", "bibliographic_titleLang": "en"}]}]}, "item_10_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The existence of synchronous multiple primary malignant tumors was not a significant risk factor for patients with newly diagnosed hematological malignancies. It is important to provide adequate treatment to both hematological malignancies and solid tumors appropriately. Background: Hematological malignancies are occasionally observed with synchronous multiple primary malignant tumors (sMPMTs) at diagnosis. We aimed to clarify the impact of sMPMTs on newly diagnosed hematological malignancies and determine the optimal treatment strategies. Patients and Methods: We analyzed the outcomes of 649 patients with hematological malignancies, including 19 patients with sMPMTs (2.9%), and compared the outcomes between patients with and without sMPMTs. Results: The overall survival (OS) and disease-free survival (DFS) rates for patients with sMPMTs were 77% and 70%, respectively, at 2 years; these rates were not statistically different from those for patients without sMPMTs (P = .17 and P = .64, respectively). Multivariate analysis showed that the presence of sMPMTs was not a significant prognostic factor for OS, DFS, or relapse (hazard ratio [HR] 1.48, 95% confidence interval [CI] 0.65-3.38, P = .35; HR 0.97, 95% CI 0.46-2.10, P = .97; and HR 0.79, 95% CI 0.29-2.14, P= .65). In patients with sMPMTs, the order of treatment was not a significant prognostic factor. However, discontinuation of treatment was a marginally favorable factor and might reflect a selection bias. Conclusion: The presence of sMPMTs was not a significant risk factor for patients with newly diagnosed hematological malignancies. It is important to provide adequate treatment for both hematological malignancies and solid tumors at the physician’s discretion.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "DOI", "subitem_identifier_uri": "http://doi.org/10.1016/j.clml.2017.09.006"}, {"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/27362"}]}, "item_10_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier", "subitem_publisher_language": "en"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1016/j.clml.2017.09.006", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/", "subitem_rights_language": "en"}]}, "item_10_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "2152-2650", "subitem_source_identifier_type": "PISSN"}]}, "item_1615787544753": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Nishiwaki, Satoshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "75038", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okuno, Shingo", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "75039", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Suzuki, Kotaro", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "75040", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kurahashi, Shingo", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "75041", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sugiura, Isamu", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "75042", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-12-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "CLML_2017_435_Original_accepted_V1.pdf", "filesize": [{"value": "359.0 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 359000.0, "url": {"label": "CLML_2017_435_Original_accepted_V1.pdf ファイル公開日: 2018/12/01", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/25141/files/CLML_2017_435_Original_accepted_V1.pdf"}, "version_id": "0937d703-a1e4-46df-9616-41f02c90e7c6"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Hematological malignancies", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Order of treatment", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Solid tumors", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Synchronous multiple primary malignant tumors", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Treatment discontinuation", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Impact of Synchronous Multiple Primary Malignant Tumors on Newly Diagnosed Hematological Malignancies", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Impact of Synchronous Multiple Primary Malignant Tumors on Newly Diagnosed Hematological Malignancies", "subitem_title_language": "en"}]}, "item_type_id": "10", "owner": "1", "path": ["501"], "permalink_uri": "http://hdl.handle.net/2237/27362", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2018-02-06"}, "publish_date": "2018-02-06", "publish_status": "0", "recid": "25141", "relation": {}, "relation_version_is_last": true, "title": ["Impact of Synchronous Multiple Primary Malignant Tumors on Newly Diagnosed Hematological Malignancies"], "weko_shared_id": -1}