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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Perioperative Serum Carcinoembryonic Antigen Levels Predict Recurrence and Survival of Patients with Pathological T2-4 Gastric Cancer Treated with Curative Gastrectomy

http://hdl.handle.net/2237/00027917
http://hdl.handle.net/2237/00027917
ca71bbb6-da7b-4a90-9fe5-a0dde9e90c42
名前 / ファイル ライセンス アクション
Perioperative_Serum_Carcinoembryonic_Antigen_Level.pdf Perioperative_Serum_Carcinoembryonic_Antigen_Level (1.1 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2018-04-17
タイトル
タイトル Perioperative Serum Carcinoembryonic Antigen Levels Predict Recurrence and Survival of Patients with Pathological T2-4 Gastric Cancer Treated with Curative Gastrectomy
言語 en
著者 Uda, Hiroaki

× Uda, Hiroaki

WEKO 76149

en Uda, Hiroaki

Search repository
Kanda, Mitsuro

× Kanda, Mitsuro

WEKO 76150

en Kanda, Mitsuro

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Tanaka, Chie

× Tanaka, Chie

WEKO 76151

en Tanaka, Chie

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Kobayashi, Daisuke

× Kobayashi, Daisuke

WEKO 76152

en Kobayashi, Daisuke

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Inaoka, Kenichi

× Inaoka, Kenichi

WEKO 76153

en Inaoka, Kenichi

Search repository
Tanaka, Yuri

× Tanaka, Yuri

WEKO 76154

en Tanaka, Yuri

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Hayashi, Masamichi

× Hayashi, Masamichi

WEKO 76155

en Hayashi, Masamichi

Search repository
Iwata, Naoki

× Iwata, Naoki

WEKO 76156

en Iwata, Naoki

Search repository
Yamada, Suguru

× Yamada, Suguru

WEKO 76157

en Yamada, Suguru

Search repository
Fujii, Tsutomu

× Fujii, Tsutomu

WEKO 76158

en Fujii, Tsutomu

Search repository
Sugimoto, Hiroyuki

× Sugimoto, Hiroyuki

WEKO 76159

en Sugimoto, Hiroyuki

Search repository
Murotani, Kenta

× Murotani, Kenta

WEKO 76160

en Murotani, Kenta

Search repository
Fujiwara, Michitaka

× Fujiwara, Michitaka

WEKO 76161

en Fujiwara, Michitaka

Search repository
Kodera, Yasuhiro

× Kodera, Yasuhiro

WEKO 76162

en Kodera, Yasuhiro

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 This is the accepted manuscript version of an article published by S. Karger AG in [Digestive Surgery/2017/35/1/55-63 DOI:10.1159/000471931] and available on www.karger.com/Article/FullText/471931.
キーワード
主題Scheme Other
主題 Gastric cancer
キーワード
主題Scheme Other
主題 Carcinoembryonic antigen
キーワード
主題Scheme Other
主題 Carbohydrate antigen 19-9
キーワード
主題Scheme Other
主題 Prognosis
抄録
内容記述 Background/Aims: Do serum carcinoembryonic antigen (CEA) and carbohydrate antigen (CA) 19-9 levels serve as prognostic indicators in patients with gastric cancer (GC)? This is a question that has long been disputed. The aim of this study was to evaluate the significance of perioperative serum levels of CEA and CA19-9 for predicting the recurrence and long-term survival after patients with pT2-4 GC undergo curative gastrectomy. Methods: This study included 251 patients with radically resected pT2-4 GC without preoperative treatment. Associations between the preoperative and postoperative serum levels of CEA or CA19-9 and postoperative long-term outcomes and recurrence patterns were evaluated. Results: Preoperative CEA >5.0 ng/mL was an independent prognostic factor of overall survival. Elevation of both preoperative CEA and CA19-9 levels showed no synergistic adverse effects on prognosis. Preoperative levels of these markers achieved superior predictive performance compared with the postoperative values. Adverse prognosis is significantly associated with persistent elevation of CEA levels before and after gastrectomy. Elevation of CEA levels, particularly at postoperative measurement, was significantly associated with hematogenous recurrence. Conclusion: Determination of perioperative CEA levels facilitated predictions of recurrence patterns and prognosis among patients with pT2-4 GC who underwent curative gastrectomy.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 ファイル公開日: 2018/12/01
言語 ja
内容記述タイプ Other
出版者
言語 en
出版者 Karger
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1159/000471931
ISSN
収録物識別子タイプ PISSN
収録物識別子 0253-4886
書誌情報 en : Digestive Surgery

巻 35, 号 1, p. 55-63, 発行日 2017-12
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