{"_buckets": {"deposit": "505eb0d0-3b64-45a2-9f35-57cf74deffd6"}, "_deposit": {"id": "25721", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "25721"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00025721", "sets": ["667"]}, "author_link": ["76244", "76245"], "item_10_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2017-10", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "5", "bibliographicPageEnd": "485", "bibliographicPageStart": "475", "bibliographicVolumeNumber": "31", "bibliographic_titles": [{"bibliographic_title": "Best Practice \u0026 Research Clinical Endocrinology \u0026 Metabolism", "bibliographic_titleLang": "en"}]}]}, "item_10_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Thyroid hormones (TH) are important for development, growth, and metabolism. It is also clear that the synthesis and secretion of TH are regulated by the hypothalamic–pituitary–thyroid (HPT) axis. Animal models have helped advance our understanding of the roles and regulatory mechanisms of TH. The animals\u0027 bodies develop through coordinated timing of cell division and differentiation. Studies of frog metamorphosis led to the discovery of TH and their role in development. However, to adapt to rhythmic environmental changes, animals also developed various endocrine rhythms. Studies of rodents clarified the neural and molecular mechanisms underlying the circadian regulation of the HPT axis. Moreover, birds have a sophisticated seasonal adaptation mechanism, and recent studies of quail revealed unexpected roles for thyroid-stimulating hormone (TSH) and TH in the seasonal regulation of reproduction. Interestingly, this mechanism is conserved in mammals. Thus, we review how animal studies have shaped our general understanding of the HPT axis in relation to biological rhythms.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10_description_5": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "ファイル公開：2018-10-01 ", "subitem_description_language": "ja", "subitem_description_type": "Other"}]}, "item_10_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier", "subitem_publisher_language": "en"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1016/j.beem.2017.09.002", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/", "subitem_rights_language": "en"}]}, "item_10_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1521690X", "subitem_source_identifier_type": "PISSN"}]}, "item_1615787544753": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Ikegami, Keisuke", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "76244", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshimura, Takashi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "76245", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-10-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Ikegami-Yoshimura_BestPractice.pdf", "filesize": [{"value": "866.6 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 866600.0, "url": {"label": "Ikegami-Yoshimura_BestPractice", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/25721/files/Ikegami-Yoshimura_BestPractice.pdf"}, "version_id": "cd2fe7c3-b4de-41c3-80fb-9bd0e788761a"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "seasonal reproduction", "subitem_subject_scheme": "Other"}, {"subitem_subject": "photoperiod", "subitem_subject_scheme": "Other"}, {"subitem_subject": "pars tuberalis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "glycosylation", "subitem_subject_scheme": "Other"}, {"subitem_subject": "amphibian metamorphosis", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "The hypothalamic–pituitary–thyroid axis and biological rhythms: The discovery of TSH\u0027s unexpected role using animal models", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "The hypothalamic–pituitary–thyroid axis and biological rhythms: The discovery of TSH\u0027s unexpected role using animal models", "subitem_title_language": "en"}]}, "item_type_id": "10", "owner": "1", "path": ["667"], "permalink_uri": "http://hdl.handle.net/2237/00027929", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2018-04-23"}, "publish_date": "2018-04-23", "publish_status": "0", "recid": "25721", "relation": {}, "relation_version_is_last": true, "title": ["The hypothalamic–pituitary–thyroid axis and biological rhythms: The discovery of TSH\u0027s unexpected role using animal models"], "weko_shared_id": -1}