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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 80(2)

Practice management for elderly patients with breast cancer; Findings from a survey by the Japan Breast Cancer Study Group

https://doi.org/10.18999/nagjms.80.2.217
https://doi.org/10.18999/nagjms.80.2.217
0b98677b-5c95-4de3-a5ae-0c084d8c16bb
名前 / ファイル ライセンス アクション
08_Sawaki.pdf 08_Sawaki.pdf (499.2 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2018-05-28
タイトル
タイトル Practice management for elderly patients with breast cancer; Findings from a survey by the Japan Breast Cancer Study Group
著者 Sawaki, Masataka

× Sawaki, Masataka

WEKO 77296

Sawaki, Masataka

Search repository
Tamura, Kenji

× Tamura, Kenji

WEKO 77297

Tamura, Kenji

Search repository
Shimomura, Akihiko

× Shimomura, Akihiko

WEKO 77298

Shimomura, Akihiko

Search repository
Taki, Yumiko

× Taki, Yumiko

WEKO 77299

Taki, Yumiko

Search repository
Nagashima, Fumio

× Nagashima, Fumio

WEKO 77300

Nagashima, Fumio

Search repository
Iwata, Hiroji

× Iwata, Hiroji

WEKO 77301

Iwata, Hiroji

Search repository
キーワード
主題Scheme Other
主題 breast cancer
キーワード
主題Scheme Other
主題 elderly
キーワード
主題Scheme Other
主題 practice management
キーワード
主題Scheme Other
主題 survey
抄録
内容記述 Information on patterns of clinical care for elderly breast cancer patients is lacking. The aims of this study are two-fold, firstly, to clarify daily practice treatments for elderly breast cancer patients in Japan, and secondly, to plan a prospective clinical trial to address unresolved clinical questions. We investigated practice care of elderly breast cancer patients in 38 institutions of the Japan Clinical Oncology Group (JCOG). Questionnaires asked: (1) definition of “elderly” for each treatment, (2) clinical standard anti-HER2 therapy in each age-group, (3) recommended docetaxel dose in each age-group, (4) considerations for future clinical trials, and (5) other information about geriatric oncology concerning breast cancer. The upper age-limit for surgery and irradiation therapy was generally 80 years, while many physicians considered anti-cytotoxic adjuvant therapy unsuitable for patients >70–75 years. For HER2-positive metastatic breast cancer, 82% of physicians recommended docetaxel (DTX) plus trastuzumab plus pertuzumab (DTP) as standard care for patients aged 65–70, although 54% of physicians avoided DTP for those aged 71–75 as first-line standard preference. Most physicians recommended 75 mg/m2 DTX for both 65–70 (63%) and 70–75 (52%) age-groups, but not for those over 75. Many physicians (73%) recommended 60 mg/m2 DTX first. Most (97%) agree that the vulnerability of each elderly patient in a clinical trial should be assessed by comprehensive geriatric assessment. This is the first questionnaire study of care patterns for elderly breast cancer patients. Physicians considered different drug regimens and dosages according to patients’ fragility.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.80.2.217
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/802.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 80, 号 2, p. 217-226, 発行日 2018-05
著者版フラグ
値 publisher
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