ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "0af50fc7-b92e-4182-88ad-42b79dddd371"}, "_deposit": {"id": "26091", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "26091"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00026091", "sets": ["501"]}, "author_link": ["78205", "78206", "78207", "78208", "78209", "78210", "78211", "78212", "78213", "78214", "78215", "78216", "78217", "78218", "78219", "78220", "78221", "78222", "78223", "78224", "78225", "78226", "78227", "78228", "78229", "78230", "78231"], "item_10_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2018-03", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "27", "bibliographicPageStart": "20", "bibliographicVolumeNumber": "66", "bibliographic_titles": [{"bibliographic_title": "Leukemia Research", "bibliographic_titleLang": "en"}]}]}, "item_10_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Many genetic alterations that are associated with the prognosis of acute myeloid leukemia (AML) have been identified, and several risk stratification systems based on the genetic status have been recommended. The European LeukemiaNet (ELN) first proposed the risk stratification system for AML in 2010 (ELN-2010), and recently published the revised system (ELN-2017). We validated the long-term prognosis and clinical characteristics of each ELN-2017 risk category in Japanese adult AML patients who were treated in the Japan Adult Leukemia Study Group (JALSG) AML-201 study. We demonstrated that the 3-risk category system of the ELN-2017 successfully discriminated the overall survival and complete remission rates in our cohort in comparison with the 4-risk category of the ELN-2010. However, there were still genetic categories in which stratification of patients into favorable or intermediate risk categories was controversial; the low allelic ratio of FLT3-ITD was not necessarily associated with a better prognosis in patients with FLT3-ITD, and cytogenetic abnormalities may affect the prognosis in patients with favorable genetic lesions such as NPM1 and CEBPA mutations. As many molecular targeting agents, such as FLT3 inhibitors, have been developed, we must continue to modify the genetic risk stratification system to match the progression of therapeutic strategies.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10_description_5": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "ファイル公開:2019-03-01 ", "subitem_description_language": "ja", "subitem_description_type": "Other"}]}, "item_10_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier", "subitem_publisher_language": "en"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1016/j.leukres.2018.01.008", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/", "subitem_rights_language": "en"}]}, "item_10_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0145-2126", "subitem_source_identifier_type": "PISSN"}]}, "item_1615787544753": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Harada, Yasuhiko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78205", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nagata, Yasunobu", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78206", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kihara, Rika", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78207", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ishikawa, Yuichi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78208", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Asou, Norio", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78209", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ohtake, Shigeki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78210", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Miyawaki, Shuichi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78211", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sakura, Toru", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78212", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ozawa, Yukiyasu", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78213", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Usui, Noriko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78214", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kanamori, Heiwa", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78215", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ito, Yoshikazu", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78216", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Imai, Kiyotoshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78217", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Suehiro, Youko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78218", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kobayashi, Shinichi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78219", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kitamura, Kunio", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78220", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sakaida, Emiko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78221", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Onizuka, Makoto", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78222", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takeshita, Akihiro", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78223", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ishida, Fumihiro", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78224", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Suzushima, Hitoshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78225", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ishizawa, Kenichi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78226", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Naoe, Tomoki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78227", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsumura, Itaru", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78228", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Miyazaki, Yasushi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78229", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ogawa, Seishi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78230", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kiyoi, Hitoshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "78231", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-03-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Harada_et_al.pdf", "filesize": [{"value": "3.0 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 3000000.0, "url": {"label": "Harada_et_al", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/26091/files/Harada_et_al.pdf"}, "version_id": "871afeb8-df8f-4177-a72c-107910f84832"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Prognostic analysis according to the 2017 ELN risk stratification by genetics in adult acute myeloid leukemia patients treated in the Japan Adult Leukemia Study Group (JALSG) AML201 study", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Prognostic analysis according to the 2017 ELN risk stratification by genetics in adult acute myeloid leukemia patients treated in the Japan Adult Leukemia Study Group (JALSG) AML201 study", "subitem_title_language": "en"}]}, "item_type_id": "10", "owner": "1", "path": ["501"], "permalink_uri": "http://hdl.handle.net/2237/00028295", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2018-06-12"}, "publish_date": "2018-06-12", "publish_status": "0", "recid": "26091", "relation": {}, "relation_version_is_last": true, "title": ["Prognostic analysis according to the 2017 ELN risk stratification by genetics in adult acute myeloid leukemia patients treated in the Japan Adult Leukemia Study Group (JALSG) AML201 study"], "weko_shared_id": -1}
  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Prognostic analysis according to the 2017 ELN risk stratification by genetics in adult acute myeloid leukemia patients treated in the Japan Adult Leukemia Study Group (JALSG) AML201 study

http://hdl.handle.net/2237/00028295
http://hdl.handle.net/2237/00028295
8a009340-6081-4cfe-abb2-0849a71cde0f
名前 / ファイル ライセンス アクション
Harada_et_al.pdf Harada_et_al (3.0 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2018-06-12
タイトル
タイトル Prognostic analysis according to the 2017 ELN risk stratification by genetics in adult acute myeloid leukemia patients treated in the Japan Adult Leukemia Study Group (JALSG) AML201 study
言語 en
著者 Harada, Yasuhiko

× Harada, Yasuhiko

WEKO 78205

en Harada, Yasuhiko

Search repository
Nagata, Yasunobu

× Nagata, Yasunobu

WEKO 78206

en Nagata, Yasunobu

Search repository
Kihara, Rika

× Kihara, Rika

WEKO 78207

en Kihara, Rika

Search repository
Ishikawa, Yuichi

× Ishikawa, Yuichi

WEKO 78208

en Ishikawa, Yuichi

Search repository
Asou, Norio

× Asou, Norio

WEKO 78209

en Asou, Norio

Search repository
Ohtake, Shigeki

× Ohtake, Shigeki

WEKO 78210

en Ohtake, Shigeki

Search repository
Miyawaki, Shuichi

× Miyawaki, Shuichi

WEKO 78211

en Miyawaki, Shuichi

Search repository
Sakura, Toru

× Sakura, Toru

WEKO 78212

en Sakura, Toru

Search repository
Ozawa, Yukiyasu

× Ozawa, Yukiyasu

WEKO 78213

en Ozawa, Yukiyasu

Search repository
Usui, Noriko

× Usui, Noriko

WEKO 78214

en Usui, Noriko

Search repository
Kanamori, Heiwa

× Kanamori, Heiwa

WEKO 78215

en Kanamori, Heiwa

Search repository
Ito, Yoshikazu

× Ito, Yoshikazu

WEKO 78216

en Ito, Yoshikazu

Search repository
Imai, Kiyotoshi

× Imai, Kiyotoshi

WEKO 78217

en Imai, Kiyotoshi

Search repository
Suehiro, Youko

× Suehiro, Youko

WEKO 78218

en Suehiro, Youko

Search repository
Kobayashi, Shinichi

× Kobayashi, Shinichi

WEKO 78219

en Kobayashi, Shinichi

Search repository
Kitamura, Kunio

× Kitamura, Kunio

WEKO 78220

en Kitamura, Kunio

Search repository
Sakaida, Emiko

× Sakaida, Emiko

WEKO 78221

en Sakaida, Emiko

Search repository
Onizuka, Makoto

× Onizuka, Makoto

WEKO 78222

en Onizuka, Makoto

Search repository
Takeshita, Akihiro

× Takeshita, Akihiro

WEKO 78223

en Takeshita, Akihiro

Search repository
Ishida, Fumihiro

× Ishida, Fumihiro

WEKO 78224

en Ishida, Fumihiro

Search repository
Suzushima, Hitoshi

× Suzushima, Hitoshi

WEKO 78225

en Suzushima, Hitoshi

Search repository
Ishizawa, Kenichi

× Ishizawa, Kenichi

WEKO 78226

en Ishizawa, Kenichi

Search repository
Naoe, Tomoki

× Naoe, Tomoki

WEKO 78227

en Naoe, Tomoki

Search repository
Matsumura, Itaru

× Matsumura, Itaru

WEKO 78228

en Matsumura, Itaru

Search repository
Miyazaki, Yasushi

× Miyazaki, Yasushi

WEKO 78229

en Miyazaki, Yasushi

Search repository
Ogawa, Seishi

× Ogawa, Seishi

WEKO 78230

en Ogawa, Seishi

Search repository
Kiyoi, Hitoshi

× Kiyoi, Hitoshi

WEKO 78231

en Kiyoi, Hitoshi

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 © 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
抄録
内容記述 Many genetic alterations that are associated with the prognosis of acute myeloid leukemia (AML) have been identified, and several risk stratification systems based on the genetic status have been recommended. The European LeukemiaNet (ELN) first proposed the risk stratification system for AML in 2010 (ELN-2010), and recently published the revised system (ELN-2017). We validated the long-term prognosis and clinical characteristics of each ELN-2017 risk category in Japanese adult AML patients who were treated in the Japan Adult Leukemia Study Group (JALSG) AML-201 study. We demonstrated that the 3-risk category system of the ELN-2017 successfully discriminated the overall survival and complete remission rates in our cohort in comparison with the 4-risk category of the ELN-2010. However, there were still genetic categories in which stratification of patients into favorable or intermediate risk categories was controversial; the low allelic ratio of FLT3-ITD was not necessarily associated with a better prognosis in patients with FLT3-ITD, and cytogenetic abnormalities may affect the prognosis in patients with favorable genetic lesions such as NPM1 and CEBPA mutations. As many molecular targeting agents, such as FLT3 inhibitors, have been developed, we must continue to modify the genetic risk stratification system to match the progression of therapeutic strategies.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 ファイル公開:2019-03-01
言語 ja
内容記述タイプ Other
出版者
言語 en
出版者 Elsevier
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.leukres.2018.01.008
ISSN
収録物識別子タイプ PISSN
収録物識別子 0145-2126
書誌情報 en : Leukemia Research

巻 66, p. 20-27, 発行日 2018-03
著者版フラグ
値 author
戻る
0
views
See details
Views

Versions

Ver.1 2021-03-01 12:37:52.431828
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3