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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 80(3)

Clinical significance of SUVmax on preoperative 18F-fluorodeoxyglucose positron emission tomography in patients who underwent R0-esophagectomy for esophageal cancer

https://doi.org/10.18999/nagjms.80.3.401
https://doi.org/10.18999/nagjms.80.3.401
713f2e75-5dfc-4a5b-bda7-f1c909c66628
名前 / ファイル ライセンス アクション
12_Shimizu.pdf 12_Shimizu.pdf (519.0 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2018-08-31
タイトル
タイトル Clinical significance of SUVmax on preoperative 18F-fluorodeoxyglucose positron emission tomography in patients who underwent R0-esophagectomy for esophageal cancer
著者 Shimizu, Daisuke

× Shimizu, Daisuke

WEKO 84954

Shimizu, Daisuke

Search repository
Yuasa, Norihiro

× Yuasa, Norihiro

WEKO 84955

Yuasa, Norihiro

Search repository
Miyake, Hideo

× Miyake, Hideo

WEKO 84956

Miyake, Hideo

Search repository
Takeuchi, Eiji

× Takeuchi, Eiji

WEKO 84957

Takeuchi, Eiji

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Miyata, Kanji

× Miyata, Kanji

WEKO 84958

Miyata, Kanji

Search repository
Itoh, Shigeki

× Itoh, Shigeki

WEKO 84959

Itoh, Shigeki

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キーワード
主題Scheme Other
主題 esophageal cancer
キーワード
主題Scheme Other
主題 PET
キーワード
主題Scheme Other
主題 prognostic factors
抄録
内容記述 The standardized uptake value (SUV) is a marker of tumor glucose metabolism, detected using 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) and may reflect tumor aggressiveness. The purpose of this study was to evaluate the clinical significance of maximum SUV (SUVmax) of primary esophageal cancer (EC) lesions. A total of 86 patients with EC who underwent pre-treatment FDG-PET and R0-resection were included in our study. The mean patient age was 65 years, and 87% were men. Histologically, cancers included squamous cell carcinomas, adenocarcinomas, and other tumors in 72, 3, and 11 patients, respectively. Preoperative chemotherapy with or without radiotherapy was performed in 4 and 37 patients, respectively. Measured patient outcomes included the correlation between the SUVmax of the primary EC lesion and clinicopathological factors in patients who did not undergo preoperative treatment (n = 45), and the investigation of relapse-free survival (RFS) according to SUVmax and the relationship between SUVmax and recurrence sites in all patients (n=86). The mean SUVmax was 8.9 ± 4.6, and SUVmax values significantly correlated with tumor invasion depth and stage. The 5-year RFS for the enrolled patients was 57%, and the RFS of patients with SUVmax < 7.0 was better than that of patients with SUVmax ≥ 7.0, with a marginal difference (p = 0.0892). Lymph node recurrences were significantly more common in patients with SUVmax ≥ 7.0, compared to patients with SUVmax < 7.0. Therefore, the SUVmax value of the primary EC lesion before preoperative treatment may be predictive of RFS and lymph node recurrence.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.80.3.401
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/803.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 80, 号 3, p. 401-409, 発行日 2018-08
著者版フラグ
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