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A survival analysis using physique-adjusted tumor size of non-small cell lung cancer
http://hdl.handle.net/2237/00029076
http://hdl.handle.net/2237/00029076d1dd9773-3b66-4529-89ea-be6cbe08bb16
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-11-20 | |||||
| タイトル | ||||||
| タイトル | A survival analysis using physique-adjusted tumor size of non-small cell lung cancer | |||||
| 言語 | en | |||||
| 著者 |
Ozeki, Naoki
× Ozeki, Naoki× Fukui, Takayuki× Kawaguchi, Koji× Nakamura, Shota× Hakiri, Shuhei× Kato, Taketo× Hirakawa, Akihiro× Yokoi, Kohei |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 権利 | ||||||
| 言語 | en | |||||
| 権利情報 | “This is a post-peer-review, pre-copyedit version of an article published in [International Journal of Clinical Oncology]. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10147-017-1219-6”. | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Lung cancer | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Body size | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Height | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Weight | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | BMI | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Survival | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background: Differences in individual body sizes have not been well considered when analyzing the survival of patients with non-small cell lung cancer (NSCLC). We hypothesized that physique-adjusted tumor size is superior to actual tumor size in predicting the prognosis. Methods: Eight hundred and forty-two patients who underwent R0 resection of NSCLC between 2005 and 2012 were retrospectively reviewed, and overall survival (OS) was evaluated. The physique-adjusted tumor size was defined as: x-adjusted tumor size = tumor size × mean value of x/individual value of x [x = height, weight, body surface area (BSA), or body mass index (BMI)]. Tumor size category was defined as ≤2, 2–3, 3–5, 5–7, and >7 cm. The separation index (SEP), which is the weighted mean of the absolute value of estimated regression coefficients over the subgroups with respect to a reference group, was used to measure the separation of subgroups. Results: The mean values of height, weight, BSA, and BMI were 160.7 cm, 57.6 kg, 1.59 m2, and 22.2 kg/m2, respectively. The 5-year survival rates ranged from 88−59% in the non-adjusted tumor size model (SEP 1.937), from 90−57% in the height-adjusted model (SEP 2.236), from 91−52% in the weight-adjusted model (SEP 2.146), from 90−56% in the BSA-adjusted model (SEP 2.077), and from 91−51% in the BMI-adjusted model (SEP 2.169). Conclusions: The physique-adjusted tumor size can separate the survival better than the actual tumor size. | |||||
| 言語 | en | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | ファイル公開：2019/04/01 | |||||
| 言語 | ja | |||||
| 出版者 | ||||||
| 出版者 | Springer | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 出版タイプ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1007/s10147-017-1219-6 | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 1341-9625 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 1437-7772 | |||||
| 書誌情報 |
en : International Journal of Clinical Oncology 巻 23, 号 2, p. 266-274, 発行日 2018-04 |
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| 著者版フラグ | ||||||
| 値 | author | |||||
