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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

A survival analysis using physique-adjusted tumor size of non-small cell lung cancer

http://hdl.handle.net/2237/00029076
http://hdl.handle.net/2237/00029076
d1dd9773-3b66-4529-89ea-be6cbe08bb16
名前 / ファイル ライセンス アクション
manuscript.pdf manuscript (311.2 kB)
Figure1.pdf Figure1 (4.4 MB)
Figure2.pdf Figure2 (4.2 MB)
table.pdf table (364.1 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2018-11-20
タイトル
タイトル A survival analysis using physique-adjusted tumor size of non-small cell lung cancer
言語 en
著者 Ozeki, Naoki

× Ozeki, Naoki

WEKO 88009

en Ozeki, Naoki

Search repository
Fukui, Takayuki

× Fukui, Takayuki

WEKO 88010

en Fukui, Takayuki

Search repository
Kawaguchi, Koji

× Kawaguchi, Koji

WEKO 88011

en Kawaguchi, Koji

Search repository
Nakamura, Shota

× Nakamura, Shota

WEKO 88012

en Nakamura, Shota

Search repository
Hakiri, Shuhei

× Hakiri, Shuhei

WEKO 88013

en Hakiri, Shuhei

Search repository
Kato, Taketo

× Kato, Taketo

WEKO 88014

en Kato, Taketo

Search repository
Hirakawa, Akihiro

× Hirakawa, Akihiro

WEKO 88015

en Hirakawa, Akihiro

Search repository
Yokoi, Kohei

× Yokoi, Kohei

WEKO 88016

en Yokoi, Kohei

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 “This is a post-peer-review, pre-copyedit version of an article published in [International Journal of Clinical Oncology]. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10147-017-1219-6”.
キーワード
主題Scheme Other
主題 Lung cancer
キーワード
主題Scheme Other
主題 Body size
キーワード
主題Scheme Other
主題 Height
キーワード
主題Scheme Other
主題 Weight
キーワード
主題Scheme Other
主題 BMI
キーワード
主題Scheme Other
主題 Survival
抄録
内容記述 Background: Differences in individual body sizes have not been well considered when analyzing the survival of patients with non-small cell lung cancer (NSCLC). We hypothesized that physique-adjusted tumor size is superior to actual tumor size in predicting the prognosis. Methods: Eight hundred and forty-two patients who underwent R0 resection of NSCLC between 2005 and 2012 were retrospectively reviewed, and overall survival (OS) was evaluated. The physique-adjusted tumor size was defined as: x-adjusted tumor size = tumor size × mean value of x/individual value of x [x = height, weight, body surface area (BSA), or body mass index (BMI)]. Tumor size category was defined as ≤2, 2–3, 3–5, 5–7, and >7 cm. The separation index (SEP), which is the weighted mean of the absolute value of estimated regression coefficients over the subgroups with respect to a reference group, was used to measure the separation of subgroups. Results: The mean values of height, weight, BSA, and BMI were 160.7 cm, 57.6 kg, 1.59 m2, and 22.2 kg/m2, respectively. The 5-year survival rates ranged from 88−59% in the non-adjusted tumor size model (SEP 1.937), from 90−57% in the height-adjusted model (SEP 2.236), from 91−52% in the weight-adjusted model (SEP 2.146), from 90−56% in the BSA-adjusted model (SEP 2.077), and from 91−51% in the BMI-adjusted model (SEP 2.169). Conclusions: The physique-adjusted tumor size can separate the survival better than the actual tumor size.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 ファイル公開:2019/04/01
言語 ja
内容記述タイプ Other
出版者
言語 en
出版者 Springer
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1007/s10147-017-1219-6
ISSN(print)
収録物識別子タイプ PISSN
収録物識別子 1341-9625
ISSN(Online)
収録物識別子タイプ EISSN
収録物識別子 1437-7772
書誌情報 en : International Journal of Clinical Oncology

巻 23, 号 2, p. 266-274, 発行日 2018-04
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