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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 80(4)

Clinical T staging is superior to fluorodeoxyglucose positron emission tomography for predicting local outcomes after intra-arterial infusion chemoradiotherapy for maxillary sinus squamous cell carcinoma

https://doi.org/10.18999/nagjms.80.4.541
https://doi.org/10.18999/nagjms.80.4.541
5ded5bec-f53c-49ee-9c5d-05cfca87ebe8
名前 / ファイル ライセンス アクション
10_Doi.pdf 10_Doi.pdf (270.4 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2019-01-18
タイトル
タイトル Clinical T staging is superior to fluorodeoxyglucose positron emission tomography for predicting local outcomes after intra-arterial infusion chemoradiotherapy for maxillary sinus squamous cell carcinoma
著者 Doi, Hiroshi

× Doi, Hiroshi

WEKO 88529

Doi, Hiroshi

Search repository
Fujiwara, Masayuki

× Fujiwara, Masayuki

WEKO 88530

Fujiwara, Masayuki

Search repository
Kitajima, Kazuhiro

× Kitajima, Kazuhiro

WEKO 88531

Kitajima, Kazuhiro

Search repository
Tanooka, Masao

× Tanooka, Masao

WEKO 88532

Tanooka, Masao

Search repository
Terada, Tomonori

× Terada, Tomonori

WEKO 88533

Terada, Tomonori

Search repository
Noguchi, Kazuma

× Noguchi, Kazuma

WEKO 88534

Noguchi, Kazuma

Search repository
Ishikura, Reiichi

× Ishikura, Reiichi

WEKO 88535

Ishikura, Reiichi

Search repository
Kamikonya, Norihiko

× Kamikonya, Norihiko

WEKO 88536

Kamikonya, Norihiko

Search repository
Yamakado, Koichiro

× Yamakado, Koichiro

WEKO 88537

Yamakado, Koichiro

Search repository
キーワード
主題Scheme Other
主題 concurrency
キーワード
主題Scheme Other
主題 intensity-modulated radiation therapy
キーワード
主題Scheme Other
主題 paranasal sinus
キーワード
主題Scheme Other
主題 intra-arterial infusion chemotherapy
キーワード
主題Scheme Other
主題 maxillary sinus
キーワード
主題Scheme Other
主題 radiotherapy
抄録
内容記述 Concomitant intra-arterial infusion chemoradiotherapy (IA-CRT) has been used to treat locally advanced maxillary sinus squamous cell carcinoma (MSSCC) with positive outcomes. However, an optimal predictive prognostic factor for MSSCC treated with IA-CRT remains elusive. The aim of the present study was to assess the feasibility of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET), including volumetric parameters, to predict the prognosis of MSSCC treated with IA-CRT. Twenty-four patients with newly diagnosed MSSCC receiving FDG-PET imaging before IA-CRT treatment were analyzed in this retrospective study. All patients underwent radiotherapy with a total tumor dose of 60–66 Gy in a conventional fractionation schedule, using three-dimensional conformal radiation therapy or intensitymodulated radiation therapy. Radiotherapy was performed concurrently with concurrent intra-arterial infusion chemotherapy (cisplatin). The IA-CRT response rate was 83.33%. The 1- and 3-year survival rates were 81.30% and 64.34%, respectively. The 1- and 3-year local failure-free rates were 57.21% and 40.96%, respectively. Local failure was significantly associated with poor survival (P = 0.0152). Further, clinical T staging clearly stratified local control outcomes among patients with clinical T3 or less, T4a, and T4b (P = 0.0312). Moreover, patients with stage T4b showed a significantly poorer local control compared with T3 or less (P = 0.0103). However, FDG-PET parameters provided no significant predictive information regarding treatment outcome. To conclude, pretreatment T stage predicts local control by IA-CRT, which is associated with survival.
内容記述タイプ Abstract
内容記述
内容記述 This work was supported by a Grant-in-Aid for Young Scientists (B) Grant Number 17K16493.
内容記述タイプ Other
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.80.4.541
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/804.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 80, 号 4, p. 541-550, 発行日 2018-11
著者版フラグ
値 publisher
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