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Physiological and pathological roles of branched-chain amino acids in the regulation of protein and energy metabolism and neurological functions
http://hdl.handle.net/2237/00029272
http://hdl.handle.net/2237/00029272cfa34305-57ca-4fa0-93ed-cc4d82d048ba
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2019-02-12 | |||||
タイトル | ||||||
タイトル | Physiological and pathological roles of branched-chain amino acids in the regulation of protein and energy metabolism and neurological functions | |||||
言語 | en | |||||
著者 |
Shimomura, Yoshiharu
× Shimomura, Yoshiharu× Kitaura, Yasuyuki |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | © 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Branched-chain amino acids | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Branched-chain α-keto acid dehydrogenase | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Protein metabolism | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Glucose metabolism | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Energy metabolism | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Neurological development | |||||
抄録 | ||||||
内容記述 | Branched-chain amino acids (BCAAs: leucine, isoleucine, and valine) are essential amino acids for humans and play an important role as the building blocks of proteins. Recent studies have disclosed that free BCAAs in the tissue amino acid pool function not only as substrates for protein synthesis, but also as regulators of protein and energy metabolism. Furthermore, BCAAs are actively used as an amino group donor to synthesize glutamate in the brain. These functions of BCAAs are closely related to human health. This review summarizes the recent findings concerning physiological and pathological roles of free BCAAs in the metabolism and neurological functions. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
内容記述 | ||||||
内容記述 | ファイル公開:2019-07-01 | |||||
言語 | ja | |||||
内容記述タイプ | Other | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Elsevier | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプresource | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.phrs.2018.05.014 | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 1043-6618 | |||||
書誌情報 |
en : Pharmacological Research 巻 133, p. 215-217, 発行日 2018-07 |
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著者版フラグ | ||||||
値 | author |