{"_buckets": {"deposit": "54912832-e99a-48fb-84de-a1ce940c26bf"}, "_deposit": {"id": "27072", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "27072"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00027072"}, "item_10_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2018-07", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "217", "bibliographicPageStart": "215", "bibliographicVolumeNumber": "133", "bibliographic_titles": [{"bibliographic_title": "Pharmacological Research"}]}]}, "item_10_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Branched-chain amino acids (BCAAs: leucine, isoleucine, and valine) are essential amino acids for humans and play an important role as the building blocks of proteins. Recent studies have disclosed that free BCAAs in the tissue amino acid pool function not only as substrates for protein synthesis, but also as regulators of protein and energy metabolism. Furthermore, BCAAs are actively used as an amino group donor to synthesize glutamate in the brain. These functions of BCAAs are closely related to human health. This review summarizes the recent findings concerning physiological and pathological roles of free BCAAs in the metabolism and neurological functions.", "subitem_description_type": "Abstract"}]}, "item_10_description_5": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "\u30d5\u30a1\u30a4\u30eb\u516c\u958b\uff1a2019-07-01", "subitem_description_type": "Other"}]}, "item_10_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Elsevier"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1016/j.phrs.2018.05.014", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "\u00a9 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/"}]}, "item_10_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_61": {"attribute_name": "ISSN\uff08print\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "1043-6618", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Shimomura, Yoshiharu"}], "nameIdentifiers": [{"nameIdentifier": "88755", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kitaura, Yasuyuki"}], "nameIdentifiers": [{"nameIdentifier": "88756", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-07-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Pharm_Res_Shimomura.pdf", "filesize": [{"value": "359.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 359400.0, "url": {"label": "Pharm_Res_Shimomura", "url": "https://nagoya.repo.nii.ac.jp/record/27072/files/Pharm_Res_Shimomura.pdf"}, "version_id": "d1a8b5a5-4906-4622-9e2c-ff7bc7412965"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Branched-chain amino acids", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Branched-chain \u03b1-keto acid dehydrogenase", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Protein metabolism", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Glucose metabolism", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Energy metabolism", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Neurological development", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Physiological and pathological roles of branched-chain amino acids in the regulation of protein and energy metabolism and neurological functions", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Physiological and pathological roles of branched-chain amino acids in the regulation of protein and energy metabolism and neurological functions"}]}, "item_type_id": "10", "owner": "1", "path": ["643/666/667"], "permalink_uri": "http://hdl.handle.net/2237/00029272", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2019-02-12"}, "publish_date": "2019-02-12", "publish_status": "0", "recid": "27072", "relation": {}, "relation_version_is_last": true, "title": ["Physiological and pathological roles of branched-chain amino acids in the regulation of protein and energy metabolism and neurological functions"], "weko_shared_id": null}