ログイン
言語:

WEKO3

  • トップ
  • コミュニティ
  • ランキング
AND
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "6ff67811-564f-4fa9-97d6-fdaa8d199b14"}, "_deposit": {"id": "28024", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "28024"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00028024"}, "item_10_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2018-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "12", "bibliographicPageEnd": "3293", "bibliographicPageStart": "3285", "bibliographicVolumeNumber": "36", "bibliographic_titles": [{"bibliographic_title": "Journal of Orthopaedic Research"}]}]}, "item_10_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Spinal fusion and bone defects after injuries, removal of bone tumors, and infections require repair by implantation. In this study, we show self\u2010assembling peptide (SPG\u2010178) hydrogel\u2010induced bone healing in vivo. Posterolateral lumbar fusion and tibial intramedullary models of rabbits were prepared. In the tibia model, micro\u2010CT analysis revealed a significantly higher degree of newly formed bone matrix in the SPG\u2010178 group compared to the other groups. SEM/3D micrographs showed that the cavity filled with SPG\u2010178 had collagen fibers attached to host bone. After 28 days, samples from the SPG\u2010178 group showed significant repair of the defect. In the posterolateral lumbar fusion models, micro\u2010CT showed a tendency for a higher degree of newly formed bone matrix in the SPG\u2010178 group compared to the \u03b2\u2010TCP and bone chips only groups. Von Kossa staining showed marked new bone formation attached to the lamina that was most prominent at the implanted SPG\u2010178 composite margin. SPG\u2010178 is a material that is likely to be used in clinical applications because it has several benefits. These include its favorable bone conduction properties, its ability to act as a support for various cells and growth factors, its lack of infection risk compared with materials of animal origin such as ECM, and the ease with which it can be used to fill defects with complex shapes and be combined with a wide range of other materials.", "subitem_description_type": "Abstract"}]}, "item_10_description_5": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "\u30d5\u30a1\u30a4\u30eb\u516c\u958b\uff1a2019-12-01", "subitem_description_type": "Other"}]}, "item_10_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Wiley"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1002/jor.24109", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "\"This is the peer reviewed version of the following article: [Ando, K. , Imagama, S. , Kobayashi, K. , Ito, K. , Tsushima, M. , Morozumi, M. , Tanaka, S. , Machino, M. , Ota, K. , Nishida, K. , Nishida, Y. and Ishiguro, N. (2018), Feasibility and effects of a self\u2010assembling peptide as a scaffold in bone healing: An in vivo study in rabbit lumbar posterolateral fusion and tibial intramedullary models. J. Orthop. Res., 36: 3285-3293. doi:10.1002/jor.24109], which has been published in final form at [https://doi.org/10.1002/jor.24109]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.\""}]}, "item_10_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_61": {"attribute_name": "ISSN\uff08print\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "0736-0266", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Ando, Kei"}], "nameIdentifiers": [{"nameIdentifier": "91258", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Imagama, Shiro"}], "nameIdentifiers": [{"nameIdentifier": "91259", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kobayashi, Kazuyoshi"}], "nameIdentifiers": [{"nameIdentifier": "91260", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ito, Kenyu"}], "nameIdentifiers": [{"nameIdentifier": "91261", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tsushima, Mikito"}], "nameIdentifiers": [{"nameIdentifier": "91262", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Morozumi, Masayoshi"}], "nameIdentifiers": [{"nameIdentifier": "91263", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka, Satoshi"}], "nameIdentifiers": [{"nameIdentifier": "91264", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Machino, Masaaki"}], "nameIdentifiers": [{"nameIdentifier": "91265", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ota, Kyotaro"}], "nameIdentifiers": [{"nameIdentifier": "91266", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nishida, Koji"}], "nameIdentifiers": [{"nameIdentifier": "91267", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nishida, Yoshihiro"}], "nameIdentifiers": [{"nameIdentifier": "91268", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ishiguro, Naoki"}], "nameIdentifiers": [{"nameIdentifier": "91269", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-12-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "20180716Manuscript.pdf", "filesize": [{"value": "210.0 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 210000.0, "url": {"label": "20180716Manuscript", "url": "https://nagoya.repo.nii.ac.jp/record/28024/files/20180716Manuscript.pdf"}, "version_id": "565cf631-1e72-4cb8-9a87-d589c043226d"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "self\u2010assembling peptide", "subitem_subject_scheme": "Other"}, {"subitem_subject": "scaffold", "subitem_subject_scheme": "Other"}, {"subitem_subject": "bone healing", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Feasibility and effects of a self-assembling peptide as a scaffold in bone healing: An in vivo study in rabbit lumbar posterolateral fusion and tibial intramedullary models", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Feasibility and effects of a self-assembling peptide as a scaffold in bone healing: An in vivo study in rabbit lumbar posterolateral fusion and tibial intramedullary models"}]}, "item_type_id": "10", "owner": "1", "path": ["499/500/501"], "permalink_uri": "http://hdl.handle.net/2237/00030222", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2019-05-15"}, "publish_date": "2019-05-15", "publish_status": "0", "recid": "28024", "relation": {}, "relation_version_is_last": true, "title": ["Feasibility and effects of a self-assembling peptide as a scaffold in bone healing: An in vivo study in rabbit lumbar posterolateral fusion and tibial intramedullary models"], "weko_shared_id": null}
  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Feasibility and effects of a self-assembling peptide as a scaffold in bone healing: An in vivo study in rabbit lumbar posterolateral fusion and tibial intramedullary models

http://hdl.handle.net/2237/00030222
3ade49f8-a09a-44d9-ad35-de59b7740903
名前 / ファイル ライセンス アクション
20180716Manuscript.pdf 20180716Manuscript (210.0 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2019-05-15
タイトル
タイトル Feasibility and effects of a self-assembling peptide as a scaffold in bone healing: An in vivo study in rabbit lumbar posterolateral fusion and tibial intramedullary models
著者 Ando, Kei

× Ando, Kei

WEKO 91258

Ando, Kei

Search repository
Imagama, Shiro

× Imagama, Shiro

WEKO 91259

Imagama, Shiro

Search repository
Kobayashi, Kazuyoshi

× Kobayashi, Kazuyoshi

WEKO 91260

Kobayashi, Kazuyoshi

Search repository
Ito, Kenyu

× Ito, Kenyu

WEKO 91261

Ito, Kenyu

Search repository
Tsushima, Mikito

× Tsushima, Mikito

WEKO 91262

Tsushima, Mikito

Search repository
Morozumi, Masayoshi

× Morozumi, Masayoshi

WEKO 91263

Morozumi, Masayoshi

Search repository
Tanaka, Satoshi

× Tanaka, Satoshi

WEKO 91264

Tanaka, Satoshi

Search repository
Machino, Masaaki

× Machino, Masaaki

WEKO 91265

Machino, Masaaki

Search repository
Ota, Kyotaro

× Ota, Kyotaro

WEKO 91266

Ota, Kyotaro

Search repository
Nishida, Koji

× Nishida, Koji

WEKO 91267

Nishida, Koji

Search repository
Nishida, Yoshihiro

× Nishida, Yoshihiro

WEKO 91268

Nishida, Yoshihiro

Search repository
Ishiguro, Naoki

× Ishiguro, Naoki

WEKO 91269

Ishiguro, Naoki

Search repository
権利
権利情報 "This is the peer reviewed version of the following article: [Ando, K. , Imagama, S. , Kobayashi, K. , Ito, K. , Tsushima, M. , Morozumi, M. , Tanaka, S. , Machino, M. , Ota, K. , Nishida, K. , Nishida, Y. and Ishiguro, N. (2018), Feasibility and effects of a self‐assembling peptide as a scaffold in bone healing: An in vivo study in rabbit lumbar posterolateral fusion and tibial intramedullary models. J. Orthop. Res., 36: 3285-3293. doi:10.1002/jor.24109], which has been published in final form at [https://doi.org/10.1002/jor.24109]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions."
キーワード
主題Scheme Other
主題 self‐assembling peptide
キーワード
主題Scheme Other
主題 scaffold
キーワード
主題Scheme Other
主題 bone healing
抄録
内容記述 Spinal fusion and bone defects after injuries, removal of bone tumors, and infections require repair by implantation. In this study, we show self‐assembling peptide (SPG‐178) hydrogel‐induced bone healing in vivo. Posterolateral lumbar fusion and tibial intramedullary models of rabbits were prepared. In the tibia model, micro‐CT analysis revealed a significantly higher degree of newly formed bone matrix in the SPG‐178 group compared to the other groups. SEM/3D micrographs showed that the cavity filled with SPG‐178 had collagen fibers attached to host bone. After 28 days, samples from the SPG‐178 group showed significant repair of the defect. In the posterolateral lumbar fusion models, micro‐CT showed a tendency for a higher degree of newly formed bone matrix in the SPG‐178 group compared to the β‐TCP and bone chips only groups. Von Kossa staining showed marked new bone formation attached to the lamina that was most prominent at the implanted SPG‐178 composite margin. SPG‐178 is a material that is likely to be used in clinical applications because it has several benefits. These include its favorable bone conduction properties, its ability to act as a support for various cells and growth factors, its lack of infection risk compared with materials of animal origin such as ECM, and the ease with which it can be used to fill defects with complex shapes and be combined with a wide range of other materials.
内容記述タイプ Abstract
内容記述
内容記述 ファイル公開:2019-12-01
内容記述タイプ Other
出版者
出版者 Wiley
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1002/jor.24109
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0736-0266
書誌情報 Journal of Orthopaedic Research

巻 36, 号 12, p. 3285-3293, 発行日 2018-12
著者版フラグ
値 author
戻る
0
views
See details
Views

Versions

Ver.1 2021-03-01 10:26:55.262762
Show All versions

Share

Mendeley CiteULike Twitter Facebook Print Addthis

Cite as

Export

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by CERN Data Centre & Invenio


Powered by CERN Data Centre & Invenio