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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 81(2)

Fibrinogen levels measured by the dry hematology method are lower than those measured by the Clauss method under a high concentration of heparin

https://doi.org/10.18999/nagjms.81.2.259
https://doi.org/10.18999/nagjms.81.2.259
3d533f46-e275-4ec4-978e-d5883109ad36
名前 / ファイル ライセンス アクション
10_Suzuki.pdf 10_Suzuki.pdf (311.5 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2019-06-13
タイトル
タイトル Fibrinogen levels measured by the dry hematology method are lower than those measured by the Clauss method under a high concentration of heparin
著者 Suzuki, Shogo

× Suzuki, Shogo

WEKO 92077

Suzuki, Shogo

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Tamura, Takahiro

× Tamura, Takahiro

WEKO 92078

Tamura, Takahiro

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Hasegawa, Kazuko

× Hasegawa, Kazuko

WEKO 92079

Hasegawa, Kazuko

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Maeda, Sho

× Maeda, Sho

WEKO 92080

Maeda, Sho

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Mori, Reona

× Mori, Reona

WEKO 92081

Mori, Reona

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Kainuma, Motoshi

× Kainuma, Motoshi

WEKO 92082

Kainuma, Motoshi

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Adachi, Yushi

× Adachi, Yushi

WEKO 92083

Adachi, Yushi

Search repository
Nishiwaki, Kimitoshi

× Nishiwaki, Kimitoshi

WEKO 92084

Nishiwaki, Kimitoshi

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キーワード
主題Scheme Other
主題 fibrinogen
キーワード
主題Scheme Other
主題 dry hematology method
キーワード
主題Scheme Other
主題 heparin
抄録
内容記述 The activity of fibrinogen has been reported to decrease soon after the onset of major bleeding and to be an important determinant of the final extent of bleeding and postoperative outcome. A device that measures the perioperative fibrinogen level using the dry hematology (DH) method has recently become available. The aim of this study was to compare perioperative fibrinogen levels measured by the DH method with those measured by the conventional Clauss method and to assess the effects of heparin on these measurements. The study included 206 samples from 36 patients undergoing major surgery who received high-dose heparin (HH group, 23 samples), low-dose heparin (LH group, 57 samples), or no heparin (C group, 126 control samples). Each sample was measured using the DH and Clauss methods. After excluding samples outside the effective measurement range, the three study groups (HH group, n=23; LH group, n=49; C group, n=115) were compared. The mean fibrinogen level measured by the DH method in the HH group (87.9 ± 3.1%) was significantly lower than that measured by the Clauss method. There were no significant differences between the fibrinogen measurements obtained by the two methods between the LH and C groups. In patients on high-dose heparin, the mean fibrinogen level measured by the DH method was significantly lower than that measured by the Clauss method. When hemorrhage requires emergency treatment, a method that can measure the fibrinogen level rapidly is important. The DH method may be useful for decision-making with regard to perioperative coagulation factor replacement.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.81.2.259
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/812.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 81, 号 2, p. 259-267, 発行日 2019-05
著者版フラグ
値 publisher
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