{"_buckets": {"deposit": "c0bf3973-96b4-42ed-9678-fb784f6489e7"}, "_deposit": {"id": "28401", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "28401"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00028401"}, "item_10_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2019-04-08", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3", "bibliographicPageEnd": "154", "bibliographicPageStart": "148", "bibliographicVolumeNumber": "69", "bibliographic_titles": [{"bibliographic_title": "Pathology International"}]}]}, "item_10_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Intravascular large B\u2010cell lymphoma (IVLBCL) is a distinct disease, but the neoplastic PD\u2010L1 expression on tumor cells may vary among cases. We evaluated 10 IVLBCL autopsy cases for neoplastic PD\u2010L1 expression, and had positive results in two cases. In one case, neoplastic PD\u2010L1 expression (SP142, 28\u20108, and E1J2J clones) was dependent on the organ and anatomical site (capillaries vs. vessels) of the tumor tissue. Neoplastic PD\u2010L1 expression was found in tumor cells located in capillaries in the central nervous system, pituitary gland, kidneys, lung, and gastrointestinal tract; sinuses/sinusoids of the spleen, liver, bone marrow, and lymph nodes; and an extravascular location. However, this expression was not detected in tumor cells located in the adrenal gland, thyroid gland, pancreas, ovaries, uterus, pleura, and small or larger\u2010sized vessels of the lung. The other case showed constant neoplastic PD\u2010L1 expression on the tumor cells, and in addition to the affected organs, capillaries, and vessels with two anti\u2010PD\u2010L1 antibodies (28\u20108 and E1J2J, but not SP142). The divergence and heterogeneity of neoplastic PD\u2010L1 expression were clearly demonstrated in our cases. To the best of our knowledge, this is the first description of divergent neoplastic PD\u2010L1 expression among the affected organs and anatomical sites in IVLBCL.", "subitem_description_type": "Abstract"}]}, "item_10_description_5": {"attribute_name": "\u5185\u5bb9\u8a18\u8ff0", "attribute_value_mlt": [{"subitem_description": "\u30d5\u30a1\u30a4\u30eb\u516c\u958b\uff1a2020-04-08", "subitem_description_type": "Other"}]}, "item_10_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Wiley"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1111/pin.12757", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "\"This is the peer reviewed version of the following article: [Sakakibara, A. , Inagaki, Y. , Imaoka, E. , Sakai, Y. , Ito, M. , Ishikawa, E. , Shimada, S. , Shimada, K. , Suzuki, Y. , Nakamura, S. , Satou, A. and Kohno, K. (2019), Divergence and heterogeneity of neoplastic PD\u2010L1 expression: Two autopsy case reports of intravascular large B\u2010cell lymphoma. Pathol Int, 69: 148-154. doi:10.1111/pin.12757], which has been published in final form at [https://doi.org/10.1111/pin.12757]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.\""}]}, "item_10_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_61": {"attribute_name": "ISSN\uff08print\uff09", "attribute_value_mlt": [{"subitem_source_identifier": "1320-5463", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Sakakibara, Ayako"}], "nameIdentifiers": [{"nameIdentifier": "92939", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Inagaki, Yuichiro"}], "nameIdentifiers": [{"nameIdentifier": "92940", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Imaoka, Eiki"}], "nameIdentifiers": [{"nameIdentifier": "92941", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sakai, Yu"}], "nameIdentifiers": [{"nameIdentifier": "92942", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ito, Masafumi"}], "nameIdentifiers": [{"nameIdentifier": "92943", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ishikawa, Eri"}], "nameIdentifiers": [{"nameIdentifier": "92944", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shimada, Satoko"}], "nameIdentifiers": [{"nameIdentifier": "92945", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shimada, Kazuyuki"}], "nameIdentifiers": [{"nameIdentifier": "92946", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Suzuki, Yuka"}], "nameIdentifiers": [{"nameIdentifier": "92947", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakamura, Shigeo"}], "nameIdentifiers": [{"nameIdentifier": "92948", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Satou, Akira"}], "nameIdentifiers": [{"nameIdentifier": "92949", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kohno, Kei"}], "nameIdentifiers": [{"nameIdentifier": "92950", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-04-08"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "A_Sakakibara.pdf", "filesize": [{"value": "155.6 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 155600.0, "url": {"label": "A_Sakakibara", "url": "https://nagoya.repo.nii.ac.jp/record/28401/files/A_Sakakibara.pdf"}, "version_id": "10a9ec05-8a54-4947-be9b-2286d69bba24"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "autopsy", "subitem_subject_scheme": "Other"}, {"subitem_subject": "intravascular large B\u2010cell lymphoma", "subitem_subject_scheme": "Other"}, {"subitem_subject": "neoplastic PD\u2010L1 expression divergence or heterogeneity", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Divergence and heterogeneity of neoplastic PD\u2010L1 expression: Two autopsy case reports of intravascular large B\u2010cell lymphoma", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Divergence and heterogeneity of neoplastic PD\u2010L1 expression: Two autopsy case reports of intravascular large B\u2010cell lymphoma"}]}, "item_type_id": "10", "owner": "1", "path": ["499/500/501"], "permalink_uri": "http://hdl.handle.net/2237/00030594", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_name_i18n": "\u516c\u958b\u65e5", "attribute_value": "2019-08-09"}, "publish_date": "2019-08-09", "publish_status": "0", "recid": "28401", "relation": {}, "relation_version_is_last": true, "title": ["Divergence and heterogeneity of neoplastic PD\u2010L1 expression: Two autopsy case reports of intravascular large B\u2010cell lymphoma"], "weko_shared_id": null}