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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 81(3)

Renewed Japanese spirometric reference variables and risk stratification for postoperative outcomes in COPD patients with resected lung cancer

https://doi.org/10.18999/nagjms.81.3.427
https://doi.org/10.18999/nagjms.81.3.427
3a3761e9-09f8-4d7a-ad85-4d1bb9826eb0
名前 / ファイル ライセンス アクション
08_Okada.pdf 08_Okada.pdf (417.6 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2019-09-04
タイトル
タイトル Renewed Japanese spirometric reference variables and risk stratification for postoperative outcomes in COPD patients with resected lung cancer
著者 Okada, Yu

× Okada, Yu

WEKO 93140

Okada, Yu

Search repository
Hashimoto, Naozumi

× Hashimoto, Naozumi

WEKO 93141

Hashimoto, Naozumi

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Iwano, Shingo

× Iwano, Shingo

WEKO 93142

Iwano, Shingo

Search repository
Kawaguchi, Koji

× Kawaguchi, Koji

WEKO 93143

Kawaguchi, Koji

Search repository
Fukui, Takayuki

× Fukui, Takayuki

WEKO 93144

Fukui, Takayuki

Search repository
Sakamoto, Koji

× Sakamoto, Koji

WEKO 93145

Sakamoto, Koji

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Wakai, Kenji

× Wakai, Kenji

WEKO 93146

Wakai, Kenji

Search repository
Yokoi, Kohei

× Yokoi, Kohei

WEKO 93147

Yokoi, Kohei

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Hasegawa, Yoshinori

× Hasegawa, Yoshinori

WEKO 93148

Hasegawa, Yoshinori

Search repository
キーワード
主題Scheme Other
主題 chronic obstructive lung disease
キーワード
主題Scheme Other
主題 lower limit of normal
キーワード
主題Scheme Other
主題 Japanese
キーワード
主題Scheme Other
主題 thoracic surgery
キーワード
主題Scheme Other
主題 lung cancer
抄録
内容記述 Although the lower limit of normal (LLN) of FEV1/FVC detects at-risk patients for postoperative outcomes among Japanese chronic obstructive pulmonary disease (COPD) patients with resected lung cancer, there was a lack of a Japanese reference equation to calculate the LLN of FEV1/FVC. Renewed Japanese spirometric reference variables might enable us to verify clinical impact of the LLN of FEV1/FVC among the Japanese population. To evaluate the clinical impact of the LLN of FEV1/FVC by using this renewed reference, data were retrospectively analyzed from 609 newly diagnosed lung cancer patients who had undergone thoracic surgery between 2006 and 2011. The combined assessment of the 0.70 fixed ratio and the LLN of the FEV1/FVC ratio classified the 609 subjects into the COPD (214 subjects), non-COPD (337 subjects), and in-between (58 subjects) groups, respectively. All of the relative odds ratios (ORs) of postoperative outcomes for the comparison between the in-between and non-COPD groups did not show significant confidence intervals (CIs). On the other hand, the adjusted ORs of postoperative outcomes for the COPD group versus the non-COPD group were 2.840 (95% CI: 1.824–4.421) for prolonged oxygen therapy (POT), 1.836 (95% CI: 1.166–2.890) for prolonged postoperative stays, and 1.637 (95% CI: 1.007–2.663) for combined complications. Adjusted comparisons of POT between the in-between and COPD groups also showed a significant relative OR of 2.984 (95% CI: 1.447–6.153). A standardized assessment of the LLN of FEV1/FVC by a renewed Japanese spirometric reference provides risk stratification for postoperative outcomes in the population.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.81.3.427
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/813.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 81, 号 3, p. 427-438, 発行日 2019-08
著者版フラグ
値 publisher
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