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Seasonal regulation of the lncRNA LDAIR modulates self-protective behaviours during the breeding season
http://hdl.handle.net/2237/00030676
http://hdl.handle.net/2237/00030676269b4038-af85-4012-a458-80ba6d4c0cc6
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
5517_3_merged_1551255573 (5.8 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2019-09-11 | |||||
| タイトル | ||||||
| タイトル | Seasonal regulation of the lncRNA LDAIR modulates self-protective behaviours during the breeding season | |||||
| 言語 | en | |||||
| 著者 |
Nakayama, Tomoya
× Nakayama, Tomoya× Shimmura, Tsuyoshi× Shinomiya, Ai× Okimura, Kousuke× Takehana, Yusuke× Furukawa, Yuko× Shimo, Takayuki× Senga, Takumi× Nakatsukasa, Mana× Nishimura, Toshiya× Tanaka, Minoru× Okubo, Kataaki× Kamei, Yasuhiro× Naruse, Kiyoshi× Yoshimura, Takashi |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To cope with seasonal environmental changes, animals adapt their physiology and behaviour in response to photoperiod. However, the molecular mechanisms underlying these adaptive changes are not completely understood. Here, using genome-wide expression analysis, we show that an uncharacterized long noncoding RNA (lncRNA), LDAIR, is strongly regulated by photoperiod in Japanese medaka fish (Oryzias latipes). Numerous transcripts and signalling pathways are activated during the transition from short- to long-day conditions; however, LDAIR is one of the first genes to be induced and its expression shows a robust daily rhythm under long-day conditions. Transcriptome analysis of LDAIR knockout fish reveals that the LDAIR locus regulates a gene neighbourhood, including corticotropin releasing hormone receptor 2, which is involved in the stress response. Behavioural analysis of LDAIR knockout fish demonstrates that LDAIR affects self-protective behaviours under long-day conditions. Therefore, we propose that photoperiodic regulation of corticotropin releasing hormone receptor 2 by LDAIR modulates adaptive behaviours to seasonal environmental changes. | |||||
| 言語 | en | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | ファイル公開：2019/11/01 | |||||
| 言語 | ja | |||||
| 出版者 | ||||||
| 出版者 | nature | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプresource | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | journal article | |||||
| 出版タイプ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1038/s41559-019-0866-6 | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 2397-334X | |||||
| 書誌情報 |
en : Nature Ecology & Evolution 巻 3, 号 5, p. 845-852, 発行日 2019-03 |
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| 著者版フラグ | ||||||
| 値 | author | |||||
