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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Removal of the Medial Wall of the Cavernous Sinus for Functional Pituitary Adenomas: A Technical Report and Pathologic Significance

http://hdl.handle.net/2237/00030682
http://hdl.handle.net/2237/00030682
27147284-bfa1-4be0-9449-beb41b7c38c9
名前 / ファイル ライセンス アクション
WNEU_11609_edit_report_AU.pdf WNEU_11609_edit_report_AU (306.6 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2019-09-11
タイトル
タイトル Removal of the Medial Wall of the Cavernous Sinus for Functional Pituitary Adenomas: A Technical Report and Pathologic Significance
言語 en
著者 Nagata, Yuichi

× Nagata, Yuichi

WEKO 93434

en Nagata, Yuichi

Search repository
Takeuchi, Kazuhito

× Takeuchi, Kazuhito

WEKO 93435

en Takeuchi, Kazuhito

Search repository
Yamamoto, Taiki

× Yamamoto, Taiki

WEKO 93436

en Yamamoto, Taiki

Search repository
Ishikawa, Takayuki

× Ishikawa, Takayuki

WEKO 93437

en Ishikawa, Takayuki

Search repository
Kawabata, Teppei

× Kawabata, Teppei

WEKO 93438

en Kawabata, Teppei

Search repository
Shimoyama, Yoshie

× Shimoyama, Yoshie

WEKO 93439

en Shimoyama, Yoshie

Search repository
Wakabayashi, Toshihiko

× Wakabayashi, Toshihiko

WEKO 93440

en Wakabayashi, Toshihiko

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 © 2019. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
キーワード
主題Scheme Other
主題 Acromegaly
キーワード
主題Scheme Other
主題 Cavernous sinus
キーワード
主題Scheme Other
主題 Cushing disease
キーワード
主題Scheme Other
主題 Medial wall
キーワード
主題Scheme Other
主題 Medial wall–plasty
キーワード
主題Scheme Other
主題 Medial wall removal
キーワード
主題Scheme Other
主題 Pituitary adenoma
抄録
内容記述 Background: Removal of the medial wall of the cavernous sinus (MW) is challenging for neurosurgeons. We describe a practical method of endoscopic MW removal via endonasal transsphenoidal approach to minimalize intraoperative blood loss and postoperative morbidities. We also present the pathologic significance of this technique for functional pituitary adenomas (FPAs). Methods: We performed MW removal in patients with FPA with no well-defined pseudocapsule and a tumor in direct contact with the MW. The MW was judged to have tumor invasion based on the intraoperative appearance, and it was removed regardless of the appearance of MW involvement. Intraoperative findings and postoperative clinical, endocrinologic, and pathologic outcomes were retrospectively reviewed. Results: Fourteen patients underwent MW removal for FPA, including 12 patients with acromegaly and 2 with Cushing disease. Mean intraoperative blood loss was 170 mL (range, 32–400 mL), and none of the patients required blood transfusion. Among the 7 patients without intraoperative apparent MW involvement, 4 (57.1%) had pathologically confirmed tumor invasion into the MW (occult invasion). Biochemical remission by surgery alone was achieved in 13 patients (92.9%). Transient oculomotor palsy occurred in 1 patient (7.1%). Conclusions: Occult tumor invasion into the MW was often detected in patients with FPA without a well-defined pseudocapsule but in direct contact with the MW. Our technique can enhance the effectiveness of surgery with minimal postoperative morbidities.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 ファイル公開:2020-06-01
言語 ja
内容記述タイプ Other
出版者
言語 en
出版者 Elsevier
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.wneu.2019.02.134
ISSN(print)
収録物識別子タイプ PISSN
収録物識別子 1878-8750
書誌情報 en : World Neurosurgery

巻 126, p. 53-58, 発行日 2019-06
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