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Factors related to survival discharge in trisomy 18: A retrospective multicenter study
http://hdl.handle.net/2237/00030683
http://hdl.handle.net/2237/00030683b28f1dcb-c41f-4d3b-862a-348e9e32a955
名前 / ファイル | ライセンス | アクション |
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190228_T18 (215.8 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2019-09-13 | |||||
タイトル | ||||||
タイトル | Factors related to survival discharge in trisomy 18: A retrospective multicenter study | |||||
言語 | en | |||||
著者 |
Kato, Eiko
× Kato, Eiko× Kitase, Yuma× Tachibana, Takashi× Hattori, Tetsuo× Saito, Akiko× Muramatsu, Yukako× Takemoto, Koji× Yamamoto, Hikaru× Hayashi, Seiji× Yasuda, Ayako× Kato, Yuichi× Ieda, Kuniko× Oshiro, Makoto× Sato, Yoshiaki× Hayakawa, Masahiro |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | This is the peer reviewed version of the following article: [ Kato, E, Kitase, Y, Tachibana, T, et al. Factors related to survival discharge in trisomy 18: A retrospective multicenter study. Am J Med Genet Part A. 2019; 179A: 1253– 1259. https://doi.org/10.1002/ajmg.a.61146], which has been published in final form at [https://doi.org/10.1002/ajmg.a.61146]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | cardiovascular surgery | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | extremely low birthweight infant | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | home healthcare | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | noninvasive | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | prenatal genetic test | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | trisomy 18 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Infants with trisomy 18 (T18) previously had a poor prognosis; however, the intensive care of these patients has markedly diversified the prognosis. We investigated the current situation of patients with T18, clarified factors for survival discharge, and surveyed actual home healthcare. A total of 117 patients with T18 admitted to nine institutions between 2000 and 2015 were retrospectively investigated. After excluding four patients whose outcomes were unclear, we divided 113 patients into two groups—the survival discharge group (n = 52) and the death discharge group (n = 61)—and compared maternal factors, perinatal factors, neonatal factors, and therapeutic factors between the groups. In addition, home healthcare, readmission, utilization of respite care and home nursing, and cause of death among the survival group were surveyed. Fifty‐two (44%) patients with T18 survived at discharge and their 1‐year survival rate was 29%. The survival group had a longer gestation period, larger physique, and longer survival time, compared to the death group. Independent factors associated with survival discharge were the absence of an extremely low birthweight infant (ELBWI), the absence of esophageal atresia and patent ductus arteriosus, and cardiovascular surgery. All surviving patients required some home healthcare. The most frequent cause of death was a respiratory disorder. We recommend discussing the treatment strategy with families in the presence of neonatologists or pediatric surgeons, who can explain differences in prognosis, based on the gestation period, birthweight, severity of cardiovascular disease, and cardiovascular surgery. | |||||
言語 | en | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | ファイル公開:2019-07-01 | |||||
言語 | ja | |||||
出版者 | ||||||
出版者 | Wiley | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1002/ajmg.a.61146 | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 1552-4825 | |||||
書誌情報 |
en : American Journal of Medical Genetics Part A 巻 179, 号 7, p. 1253-1259, 発行日 2019-07 |
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著者版フラグ | ||||||
値 | author |