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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Occult synchronous liver metastasis from perihilar cholangiocarcinoma

http://hdl.handle.net/2237/00030867
08daea35-2fb5-4652-b276-928cf659fb46
名前 / ファイル ライセンス アクション
ohiwa_surgery.pdf ohiwa_surgery (1.2 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2019-11-13
タイトル
タイトル Occult synchronous liver metastasis from perihilar cholangiocarcinoma
著者 Ohiwa, Takashi

× Ohiwa, Takashi

WEKO 94124

Ohiwa, Takashi

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Ebata, Tomoki

× Ebata, Tomoki

WEKO 94125

Ebata, Tomoki

Search repository
Mizuno, Takashi

× Mizuno, Takashi

WEKO 94126

Mizuno, Takashi

Search repository
Yokoyama, Yukihiro

× Yokoyama, Yukihiro

WEKO 94127

Yokoyama, Yukihiro

Search repository
Yamaguchi, Junpei

× Yamaguchi, Junpei

WEKO 94128

Yamaguchi, Junpei

Search repository
Onoe, Shunsuke

× Onoe, Shunsuke

WEKO 94129

Onoe, Shunsuke

Search repository
Watanabe, Nobuyuki

× Watanabe, Nobuyuki

WEKO 94130

Watanabe, Nobuyuki

Search repository
Nagino, Masato

× Nagino, Masato

WEKO 94131

Nagino, Masato

Search repository
権利
権利情報 © 2019. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
抄録
内容記述 Background: No authors have reported occult liver metastases from perihilar cholangiocarcinoma (PHCC), which are defined as intrahepatic metastases that are overlooked by preoperative workup and intraoperative inspection but are detected by final pathology. The aim of this study was to clarify the features of such unappreciated metastases. Methods: We reviewed retrospectively the medical records of patients with PHCC treated between 2001 and 2016 with attention to liver metastases. Results: During the study interval, 945 consecutive patients with PHCC were treated, including 260 unresected and 685 resected patients (672 with hepatectomy and 13 without). Of these, 36 patients had overt liver metastases. Of the 672 hepatectomized patients, 21 (3.1%) patients had occult liver metastases with a median number of 1 (range 1–6). When compared between occult and overt metastases, the diameter was smaller in the former (5 mm vs 12 mm, P < .001). When compared between the 21 patients with occult metastases and the 645 hepatectomized patients without liver metastases, microscopic venous invasion and lymph node metastases were observed frequently in the patients with occult metastases. Survival for these 21 patients with occult metastases was better than that for the 36 patients with overt metastases (median survival time; 17.1 vs 7.4 months, P < .01). Conclusion: Occult liver metastases from PHCC are not extremely rare. Meticulous handling of the resected specimens is crucial to detect such metastases. Although patients with occult metastases had advanced stages of the disease, their survival was better than that for patients with overt metastases.
内容記述タイプ Abstract
内容記述
内容記述 ファイル公開:2020-09-01
内容記述タイプ Other
出版者
出版者 Elsevier
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
DOI
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.surg.2019.04.029
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0039-6060
書誌情報 Surgery

巻 166, 号 3, p. 290-296, 発行日 2019-09
著者版フラグ
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