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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Left Ventricular Relaxation Half-Time as a Predictor of Cardiac Events in Idiopathic Dilated Cardiomyopathy and Hypertrophic Cardiomyopathy With Left Ventricular Systolic and/or Diastolic Dysfunction

http://hdl.handle.net/2237/00030887
http://hdl.handle.net/2237/00030887
7df6d8a6-37ff-497d-adcd-9e71cd577089
名前 / ファイル ライセンス アクション
T12_yokoi.pdf T12_yokoi (551.1 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2019-11-14
タイトル
タイトル Left Ventricular Relaxation Half-Time as a Predictor of Cardiac Events in Idiopathic Dilated Cardiomyopathy and Hypertrophic Cardiomyopathy With Left Ventricular Systolic and/or Diastolic Dysfunction
言語 en
著者 Yokoi, Tsuyoshi

× Yokoi, Tsuyoshi

WEKO 94207

en Yokoi, Tsuyoshi

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Morimoto, Ryota

× Morimoto, Ryota

WEKO 94208

en Morimoto, Ryota

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Oishi, Hideo

× Oishi, Hideo

WEKO 94209

en Oishi, Hideo

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Kato, Hiroo

× Kato, Hiroo

WEKO 94210

en Kato, Hiroo

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Arao, Yoshihito

× Arao, Yoshihito

WEKO 94211

en Arao, Yoshihito

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Yamaguchi, Shogo

× Yamaguchi, Shogo

WEKO 94212

en Yamaguchi, Shogo

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Kuwayama, Tasuku

× Kuwayama, Tasuku

WEKO 94213

en Kuwayama, Tasuku

Search repository
Haga, Tomoaki

× Haga, Tomoaki

WEKO 94214

en Haga, Tomoaki

Search repository
Hiraiwa, Hiroaki

× Hiraiwa, Hiroaki

WEKO 94215

en Hiraiwa, Hiroaki

Search repository
Kondo, Toru

× Kondo, Toru

WEKO 94216

en Kondo, Toru

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Furusawa, Kenji

× Furusawa, Kenji

WEKO 94217

en Furusawa, Kenji

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Fukaya, Kenji

× Fukaya, Kenji

WEKO 94218

en Fukaya, Kenji

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Sawamura, Akinori

× Sawamura, Akinori

WEKO 94219

en Sawamura, Akinori

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Okumura, Takahiro

× Okumura, Takahiro

WEKO 94220

en Okumura, Takahiro

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Hirashiki, Akihiro

× Hirashiki, Akihiro

WEKO 94221

en Hirashiki, Akihiro

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Murohara, Toyoaki

× Murohara, Toyoaki

WEKO 94222

en Murohara, Toyoaki

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 © 2019. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
抄録
内容記述 Purpose: Diastolic dysfunction preceding systolic dysfunction is considered an important interaction in cardiomyopathy with poor prognosis. The aim of this study was to compare left ventricular (LV) isovolumic relaxation with the other parameters as a potential prognostic marker for patients with idiopathic dilated cardiomyopathy (IDC) and hypertrophic cardiomyopathy (HC). Methods: A total of 145 patients with IDC and 116 with HC were evaluated for hemodynamic parameters; LV pressure was directly measured by a micromanometer catheter, and relaxation half-time (T1/2) was used to determine LV isovolumic relaxation. The median follow-up period was 4.7 years. Results: The mean ages of the patients with IDC and HC were 52.0 ± 12.0 and 57.1 ± 12.4 years, respectively. Each patient group was further divided into 2 groups based on the median value of T1/2: (1) <41.0 ms (D-L group) and ≥41.0 ms (D-H group) (2) <38.5 ms (H-L group) and ≥38.5 ms (H-H group). Kaplan-Meier analysis showed a significantly higher probability of cardiac events in the D-H group than in the D-L group (p = 0.001) and in the H-H group than in the H-L group (p = 0.028). Further, Cox proportional hazard regression analysis revealed that T1/2 was an independent predictor of cardiac events for patients with IDC (hazard ratio 1.109; p = 0.007) and HC (hazard ratio 1.062; p = 0.041). In conclusion, regardless of the type of cardiomyopathy, T1/2 as a measure of LV isovolumic relaxation function was found to be associated with the occurrence of cardiac events.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 ファイル公開:2020-08-01
言語 ja
内容記述タイプ Other
出版者
言語 en
出版者 Elsevier
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.amjcard.2019.05.005
ISSN(print)
収録物識別子タイプ PISSN
収録物識別子 0002-9149
書誌情報 en : The American Journal of Cardiology

巻 124, 号 3, p. 435-441, 発行日 2019-08
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