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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 81(4)

Association between green tea intake and risk of cognitive decline, considering glycated hemoglobin level, in older Japanese adults: the NILS-LSA study

https://doi.org/10.18999/nagjms.81.4.655
https://doi.org/10.18999/nagjms.81.4.655
13d12ef6-62c4-4414-9b99-977ee0c03ee7
名前 / ファイル ライセンス アクション
12_Shirai.pdf 12_Shirai.pdf (246.5 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2019-11-26
タイトル
タイトル Association between green tea intake and risk of cognitive decline, considering glycated hemoglobin level, in older Japanese adults: the NILS-LSA study
著者 Shirai, Yoshiro

× Shirai, Yoshiro

WEKO 94454

Shirai, Yoshiro

Search repository
Kuriki, Kiyonori

× Kuriki, Kiyonori

WEKO 94455

Kuriki, Kiyonori

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Otsuka, Rei

× Otsuka, Rei

WEKO 94456

Otsuka, Rei

Search repository
Kato, Yuki

× Kato, Yuki

WEKO 94457

Kato, Yuki

Search repository
Nishita, Yukiko

× Nishita, Yukiko

WEKO 94458

Nishita, Yukiko

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Tange, Chikako

× Tange, Chikako

WEKO 94459

Tange, Chikako

Search repository
Tomida, Makiko

× Tomida, Makiko

WEKO 94460

Tomida, Makiko

Search repository
Imai, Tomoko

× Imai, Tomoko

WEKO 94461

Imai, Tomoko

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Ando, Fujiko

× Ando, Fujiko

WEKO 94462

Ando, Fujiko

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Shimokata, Hiroshi

× Shimokata, Hiroshi

WEKO 94463

Shimokata, Hiroshi

Search repository
キーワード
主題Scheme Other
主題 green tea
キーワード
主題Scheme Other
主題 HbA1c
キーワード
主題Scheme Other
主題 blood glucose level
キーワード
主題Scheme Other
主題 cognitive decline
キーワード
主題Scheme Other
主題 epidemiology
抄録
内容記述 Positive and negative associations with risk of cognitive decline have been reported for glycated hemoglobin (HbA1c) level and green tea (GT) intake, respectively. This study aimed to assess whether the reduction in the risk of cognitive decline with GT intake depended on HbA1c level. The participants were aged ≥60 years at baseline in the cohort study, wherein examinations were conducted biennially from 2000 to 2012. Subjects (n=1,304) who had no cognitive decline during the first survey and who had participated in the follow-up survey at least once were included. The follow-up end point was the first screening time point for cognitive decline (Mini-Mental State Examination score <27) or the last survey participation. With reference to the Japanese Diabetes Society guideline, the cut-off points for HbA1c level were set at 5.6%, 6.0%, and 6.5%, and lower and higher groups were assigned for each cut-off point. In a multiple Cox proportional hazard model, an interaction between GT intake and HbA1c groups for cognitive decline was observed only at HbA1c 6.0% (P-value for interaction [with Bonferroni’s correction] <0.05/3). Lower risks of cognitive decline were found for the HbA1c ≥5.6%, ≥6.0%, and <6.5% groups (hazard ratios: 0.59, 0.34, and 0.77; 95% confidence intervals: 0.41–0.88, 0.19–0.61, and 0.56–1.08 for “≥4 times a day” vs. “<once a day” GT intake, respectively; P-value for trend: 0.06, <0.01, and 0.09, respectively). With respect to blood glucose level, our cohort study showed non-uniformly reduced risk of cognitive decline with GT intake among older Japanese adults.
内容記述タイプ Abstract
内容記述
内容記述 This study was also supported in part by JSPS KAKENHI (grant number: 15H02524).
内容記述タイプ Other
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.81.4.655
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/814.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 81, 号 4, p. 655-666, 発行日 2019-11
著者版フラグ
値 publisher
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