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How to improve outcomes of elderly patients with acute myeloid leukemia: era of excitement
https://doi.org/10.18999/nagjms.82.2.151
https://doi.org/10.18999/nagjms.82.2.151a59a6af2-34c6-4067-825d-716fa8b7e1a6
名前 / ファイル | ライセンス | アクション |
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01_Naoe.pdf (750.6 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2020-06-01 | |||||
タイトル | ||||||
タイトル | How to improve outcomes of elderly patients with acute myeloid leukemia: era of excitement | |||||
言語 | en | |||||
著者 |
Naoe, Tomoki
× Naoe, Tomoki |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報Resource | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
権利情報 | Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | elderly patients | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | acute myeloid leukemia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | chemotherapy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | molecule-targeted drug | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | prognosis | |||||
抄録 | ||||||
内容記述 | Among elderly patients with acute myeloid leukemia (AML), especially those who are unfit for intensive chemotherapy, a policy of reduced-intensity chemotherapy or conservative observation has been chosen, resulting in unmet medical needs. Clinical trials using anticancer drugs including antimetabolites or drugs targeted to cell cycle-related molecules failed to show superiority over conventional treatments. Recently, drugs targeted to Bcl-2, SMO, FLT3, and IDH1/2 have been shown to prolong overall survival alone or in combination with reduced-intensity chemotherapy. These treatments are likely to reshape the therapeutic landscape of AML, which will be personalized for individual patients based on leukemia genetics. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Nagoya University Graduate School of Medicine, School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.82.2.151 | |||||
ID登録タイプ | JaLC | |||||
関連情報 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/822.html | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
en : Nagoya Journal of Medical Science 巻 82, 号 2, p. 151-160, 発行日 2020-05 |
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著者版フラグ | ||||||
値 | publisher |