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Is cell block technique useful to predict histological type in patients with ovarian mass and/or body cavity fluids?
https://doi.org/10.18999/nagjms.82.2.225
https://doi.org/10.18999/nagjms.82.2.22585a34833-c1ce-4be2-88f2-1f1b995b3521
名前 / ファイル | ライセンス | アクション |
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08_Maseki.pdf (9.7 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2020-06-01 | |||||
タイトル | ||||||
タイトル | Is cell block technique useful to predict histological type in patients with ovarian mass and/or body cavity fluids? | |||||
言語 | en | |||||
著者 |
Maseki, Zenta
× Maseki, Zenta× Kajiyama, Hiroaki× Nishikawa, Eri× Satake, Tatsunari× Misawa, Toshiya× Kikkawa, Fumitaka |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報Resource | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
権利情報 | Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | epithelial ovarian cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | cell block technique | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | histological type | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | carcinomatosis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | fluid cytology | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The cell block (CB) technique is a generalized method utilized for the diagnostic evaluation of body cavity fluids. Ascites cytology is one of the most important diagnostic processes for epithelial ovarian cancer. However, in clinical practice, the usefulness of the CB method to diagnose this tumor remains unelucidated. Between 2008 and 2017, 15 peritoneal or pleural fluid samples obtained from patients with ovarian or peritoneal carcinoma or other gastrointestinal malignancies were preoperatively subjected to a diagnostic evaluation to predict the histological type and original organ. The CBs were made from 10% formalin neutral buffer solution fixed sediments of fluid samples after cytological smears were made by conventional method. Four-µm thickness sections were prepared from the cell blocks and stained with immunohistochemical method, using 16 kinds of antibodies and hematoxylin eosin staining method. The cellularity, architectural patterns, and morphological details were also studied. The median (range) age of patients was 73 (35–87) years. The clinical features were identified as follows: pleural effusion in 4, ovarian mass in 7, peritoneal dissemination in 12, para-aortic nodal swelling in one, and liver tumor in one (some overlapping). Five patients had a history of prior malignancy. Finally, we could accurately diagnose the histological type in 9 patients based on subsequent biopsy, surgery, and autopsy. In all 9 women, the clinical diagnosis, CB diagnosis and final pathological diagnosis were consistent. The CB technique may be a helpful modality for evaluating fluid cytology to obtain a final histopathologic diagnosis. | |||||
言語 | en | |||||
出版者 | ||||||
出版者 | Nagoya University Graduate School of Medicine, School of Medicine | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.82.2.225 | |||||
ID登録タイプ | JaLC | |||||
関連情報 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/822.html | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
en : Nagoya Journal of Medical Science 巻 82, 号 2, p. 225-235, 発行日 2020-05 |
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著者版フラグ | ||||||
値 | publisher |