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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 82(2)

Is cell block technique useful to predict histological type in patients with ovarian mass and/or body cavity fluids?

https://doi.org/10.18999/nagjms.82.2.225
https://doi.org/10.18999/nagjms.82.2.225
85a34833-c1ce-4be2-88f2-1f1b995b3521
名前 / ファイル ライセンス アクション
08_Maseki.pdf 08_Maseki.pdf (9.7 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2020-06-01
タイトル
タイトル Is cell block technique useful to predict histological type in patients with ovarian mass and/or body cavity fluids?
著者 Maseki, Zenta

× Maseki, Zenta

WEKO 99278

Maseki, Zenta

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Kajiyama, Hiroaki

× Kajiyama, Hiroaki

WEKO 99279

Kajiyama, Hiroaki

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Nishikawa, Eri

× Nishikawa, Eri

WEKO 99280

Nishikawa, Eri

Search repository
Satake, Tatsunari

× Satake, Tatsunari

WEKO 99281

Satake, Tatsunari

Search repository
Misawa, Toshiya

× Misawa, Toshiya

WEKO 99282

Misawa, Toshiya

Search repository
Kikkawa, Fumitaka

× Kikkawa, Fumitaka

WEKO 99283

Kikkawa, Fumitaka

Search repository
キーワード
主題Scheme Other
主題 epithelial ovarian cancer
キーワード
主題Scheme Other
主題 cell block technique
キーワード
主題Scheme Other
主題 histological type
キーワード
主題Scheme Other
主題 carcinomatosis
キーワード
主題Scheme Other
主題 fluid cytology
抄録
内容記述 The cell block (CB) technique is a generalized method utilized for the diagnostic evaluation of body cavity fluids. Ascites cytology is one of the most important diagnostic processes for epithelial ovarian cancer. However, in clinical practice, the usefulness of the CB method to diagnose this tumor remains unelucidated. Between 2008 and 2017, 15 peritoneal or pleural fluid samples obtained from patients with ovarian or peritoneal carcinoma or other gastrointestinal malignancies were preoperatively subjected to a diagnostic evaluation to predict the histological type and original organ. The CBs were made from 10% formalin neutral buffer solution fixed sediments of fluid samples after cytological smears were made by conventional method. Four-µm thickness sections were prepared from the cell blocks and stained with immunohistochemical method, using 16 kinds of antibodies and hematoxylin eosin staining method. The cellularity, architectural patterns, and morphological details were also studied. The median (range) age of patients was 73 (35–87) years. The clinical features were identified as follows: pleural effusion in 4, ovarian mass in 7, peritoneal dissemination in 12, para-aortic nodal swelling in one, and liver tumor in one (some overlapping). Five patients had a history of prior malignancy. Finally, we could accurately diagnose the histological type in 9 patients based on subsequent biopsy, surgery, and autopsy. In all 9 women, the clinical diagnosis, CB diagnosis and final pathological diagnosis were consistent. The CB technique may be a helpful modality for evaluating fluid cytology to obtain a final histopathologic diagnosis.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.82.2.225
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/822.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 82, 号 2, p. 225-235, 発行日 2020-05
著者版フラグ
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