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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 82(2)

High-flow nasal cannula therapy for acute respiratory failure in patients with interstitial pneumonia: a retrospective observational study

https://doi.org/10.18999/nagjms.82.2.301
https://doi.org/10.18999/nagjms.82.2.301
d6a39d07-15bc-4aaa-bb82-670f1322ba27
名前 / ファイル ライセンス アクション
14_Omote.pdf 14_Omote.pdf (798.2 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2020-06-01
タイトル
タイトル High-flow nasal cannula therapy for acute respiratory failure in patients with interstitial pneumonia: a retrospective observational study
著者 Omote, Norihito

× Omote, Norihito

WEKO 99326

Omote, Norihito

Search repository
Matsuda, Naoyuki

× Matsuda, Naoyuki

WEKO 99327

Matsuda, Naoyuki

Search repository
Hashimoto, Naozumi

× Hashimoto, Naozumi

WEKO 99328

Hashimoto, Naozumi

Search repository
Nishida, Kazuki

× Nishida, Kazuki

WEKO 99329

Nishida, Kazuki

Search repository
Sakamoto, Koji

× Sakamoto, Koji

WEKO 99330

Sakamoto, Koji

Search repository
Ando, Akira

× Ando, Akira

WEKO 99331

Ando, Akira

Search repository
Nakahara, Yoshio

× Nakahara, Yoshio

WEKO 99332

Nakahara, Yoshio

Search repository
Nishikimi, Mitsuaki

× Nishikimi, Mitsuaki

WEKO 99333

Nishikimi, Mitsuaki

Search repository
Higashi, Michiko

× Higashi, Michiko

WEKO 99334

Higashi, Michiko

Search repository
Matsui, Shigeyuki

× Matsui, Shigeyuki

WEKO 99335

Matsui, Shigeyuki

Search repository
Hasegawa, Yoshinori

× Hasegawa, Yoshinori

WEKO 99336

Hasegawa, Yoshinori

Search repository
キーワード
主題Scheme Other
主題 critical care
キーワード
主題Scheme Other
主題 pulmonary fibrosis
キーワード
主題Scheme Other
主題 respiratory failure
キーワード
主題Scheme Other
主題 nasal cannula
抄録
内容記述 High-flow nasal cannula (HFNC) oxygen is a therapy that has demonstrated survival benefits in acute respiratory failure (ARF). However, the role of HFNC in ARF due to interstitial pneumonia (IP) is unknown. The aim of this study was to compare the effects of HFNC therapy and non-invasive positive pressure ventilation (NPPV) in ARF due to IP. This retrospective observational study included 32 patients with ARF due to IP who were treated with HFNC (n = 13) or NPPV (n = 19). The clinical characteristics, intubation rate and 30-day mortality were analyzed and compared between the HFNC group and the NPPV group. Predictors of 30-day mortality were evaluated using a logistic regression model. HFNC group showed higher mean arterial blood pressure (median 92 mmHg; HFNC group vs 74 mmHg; NPPV group) and lower APACHEII score (median 22; HFNC group vs 27; NPPV group) than NPPV group. There was no significant difference in the intubation rate at day 30 between the HFNC group and the NPPV group (8% vs 37%: p = 0.069); the mortality rate at 30 days was 23% and 63%, respectively. HFNC therapy was a significant determinant of 30-day mortality in univariate analysis, and was confirmed to be an independent significant determinant of 30-day mortality in multivariate analysis (odds ratio, 0.148; 95% confidence interval, 0.025–0.880; p = 0.036). Our findings suggest that HFNC therapy can be a possible option for respiratory management in ARF due to IP. The results observed here warrant further investigation of HFNC therapy in randomized control trials.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.82.2.301
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/822.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 82, 号 2, p. 301-313, 発行日 2020-05
著者版フラグ
値 publisher
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