ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "e02e4e43-0332-41f7-bcf2-21f004cc540e"}, "_deposit": {"id": "30333", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "30333"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00030333", "sets": ["667"]}, "author_link": ["100630", "100631", "100632", "100633", "100634"], "item_10_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2019-10-07", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "10", "bibliographicPageEnd": "1133", "bibliographicPageStart": "1125", "bibliographicVolumeNumber": "38", "bibliographic_titles": [{"bibliographic_title": "DNA and Cell Biology", "bibliographic_titleLang": "en"}]}]}, "item_10_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Mammary gland involution is a regressive process for the gland to return to its prepregnancy state after lactation and comprises an initial reversible and second remodeling stage. Although many genes and the multiple expression profiles of their mRNAs have been found in this process, the mechanisms controlling the profiles are largely unknown. In this study, we identified and analyzed transcription factor Sox4 in mammary gland involution. Elevated expression of Sox4 gene in the first stage (48 h after weaning) was observed at the mRNA and protein levels in the mouse mammary gland. Immunohistochemistry of the involuting gland indicated that Sox4 was located in the nuclei of epithelial cells. Nuclear Sox4 was also detected in the second stage, but unlikely to be involved in cell death, one of the characteristic events of involution. To clarify the functional roles of Sox4 in involution, we introduced a model, including a normal mammary epithelial cell line, for finding candidate target genes of this transcription factor and examined its effect on tenascin C mRNA expression.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10_description_5": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "ファイル公開:2020/10/07", "subitem_description_language": "ja", "subitem_description_type": "Other"}]}, "item_10_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Mary Ann Liebert", "subitem_publisher_language": "en"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1089/dna.2019.4700", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "“Final publication is available from Mary Ann Liebert, Inc., publishers http://dx.doi.org/10.1089/dna.2019.4700”.", "subitem_rights_language": "en"}]}, "item_10_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "author"}]}, "item_10_source_id_61": {"attribute_name": "ISSN(print)", "attribute_value_mlt": [{"subitem_source_identifier": "1044-5498", "subitem_source_identifier_type": "PISSN"}]}, "item_1615787544753": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Shibayama, Hirohisa", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "100630", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamamoto, Tomomi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "100631", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Oshima, Kenzi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "100632", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsuda, Tsukasa", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "100633", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nadano, Daita", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "100634", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-10-07"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Sox4-201910-op.pdf", "filesize": [{"value": "1.8 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 1800000.0, "url": {"label": "Sox4-201910-op", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/30333/files/Sox4-201910-op.pdf"}, "version_id": "5e663930-01d8-45c7-9568-bdb710dcad0e"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "mammalian development", "subitem_subject_scheme": "Other"}, {"subitem_subject": "mammary gland involution", "subitem_subject_scheme": "Other"}, {"subitem_subject": "gene expression", "subitem_subject_scheme": "Other"}, {"subitem_subject": "transcriptional control", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Sox4", "subitem_subject_scheme": "Other"}, {"subitem_subject": "cancer", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Transcription Factor Sox4 as a Potential Player in Mammary Gland Involution", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Transcription Factor Sox4 as a Potential Player in Mammary Gland Involution", "subitem_title_language": "en"}]}, "item_type_id": "10", "owner": "1", "path": ["667"], "permalink_uri": "http://hdl.handle.net/2237/00032519", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2020-07-16"}, "publish_date": "2020-07-16", "publish_status": "0", "recid": "30333", "relation": {}, "relation_version_is_last": true, "title": ["Transcription Factor Sox4 as a Potential Player in Mammary Gland Involution"], "weko_shared_id": -1}
  1. B300 農学部/生命農学研究科
  2. B300a 雑誌掲載論文
  3. 学術雑誌

Transcription Factor Sox4 as a Potential Player in Mammary Gland Involution

http://hdl.handle.net/2237/00032519
http://hdl.handle.net/2237/00032519
ed457871-98bc-432d-a4ce-6e1983ab412d
名前 / ファイル ライセンス アクション
Sox4-201910-op.pdf Sox4-201910-op (1.8 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2020-07-16
タイトル
タイトル Transcription Factor Sox4 as a Potential Player in Mammary Gland Involution
言語 en
著者 Shibayama, Hirohisa

× Shibayama, Hirohisa

WEKO 100630

en Shibayama, Hirohisa

Search repository
Yamamoto, Tomomi

× Yamamoto, Tomomi

WEKO 100631

en Yamamoto, Tomomi

Search repository
Oshima, Kenzi

× Oshima, Kenzi

WEKO 100632

en Oshima, Kenzi

Search repository
Matsuda, Tsukasa

× Matsuda, Tsukasa

WEKO 100633

en Matsuda, Tsukasa

Search repository
Nadano, Daita

× Nadano, Daita

WEKO 100634

en Nadano, Daita

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利
言語 en
権利情報 “Final publication is available from Mary Ann Liebert, Inc., publishers http://dx.doi.org/10.1089/dna.2019.4700”.
キーワード
主題Scheme Other
主題 mammalian development
キーワード
主題Scheme Other
主題 mammary gland involution
キーワード
主題Scheme Other
主題 gene expression
キーワード
主題Scheme Other
主題 transcriptional control
キーワード
主題Scheme Other
主題 Sox4
キーワード
主題Scheme Other
主題 cancer
抄録
内容記述 Mammary gland involution is a regressive process for the gland to return to its prepregnancy state after lactation and comprises an initial reversible and second remodeling stage. Although many genes and the multiple expression profiles of their mRNAs have been found in this process, the mechanisms controlling the profiles are largely unknown. In this study, we identified and analyzed transcription factor Sox4 in mammary gland involution. Elevated expression of Sox4 gene in the first stage (48 h after weaning) was observed at the mRNA and protein levels in the mouse mammary gland. Immunohistochemistry of the involuting gland indicated that Sox4 was located in the nuclei of epithelial cells. Nuclear Sox4 was also detected in the second stage, but unlikely to be involved in cell death, one of the characteristic events of involution. To clarify the functional roles of Sox4 in involution, we introduced a model, including a normal mammary epithelial cell line, for finding candidate target genes of this transcription factor and examined its effect on tenascin C mRNA expression.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 ファイル公開:2020/10/07
言語 ja
内容記述タイプ Other
出版者
言語 en
出版者 Mary Ann Liebert
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1089/dna.2019.4700
ISSN(print)
収録物識別子タイプ PISSN
収録物識別子 1044-5498
書誌情報 en : DNA and Cell Biology

巻 38, 号 10, p. 1125-1133, 発行日 2019-10-07
著者版フラグ
値 author
戻る
0
views
See details
Views

Versions

Ver.1 2021-03-01 08:53:39.514383
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3