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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 82(3)

Heparin concentration in cell salvage during heparinization: a pilot study

https://doi.org/10.18999/nagjms.82.3.449
https://doi.org/10.18999/nagjms.82.3.449
fa09f957-9860-4982-9111-0d6ed27ab713
名前 / ファイル ライセンス アクション
07_Tamura.pdf 07_Tamura.pdf (238.4 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2020-09-04
タイトル
タイトル Heparin concentration in cell salvage during heparinization: a pilot study
著者 Tamura, Takahiro

× Tamura, Takahiro

WEKO 101037

Tamura, Takahiro

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Waters, Jonathan H

× Waters, Jonathan H

WEKO 101038

Waters, Jonathan H

Search repository
Nishiwaki, Kimitosi

× Nishiwaki, Kimitosi

WEKO 101039

Nishiwaki, Kimitosi

Search repository
キーワード
主題Scheme Other
主題 cell salvage
キーワード
主題Scheme Other
主題 heparin
キーワード
主題Scheme Other
主題 heparinization
キーワード
主題Scheme Other
主題 salvaged blood
キーワード
主題Scheme Other
主題 concentration
抄録
内容記述 Cell salvage is frequently used to avoid unnecessary allogeneic blood transfusions, which results in a reduction in blood transfusion volume and cost. The aspirated blood is washed with normal saline and centrifuged to recover only blood cells, salvaged blood is then made. In cardiovascular surgery, heparin is used to maintain activated clotting time over 400 seconds. Some practitioners believe that heparin remains in the salvaged blood. Therefore, we hypothesized that salvaged blood during cardiovascular surgery includes heparin. A pilot study was conducted to evaluate our hypothesis using three different salvage systems. This study was a prospective, observational, pilot study, with patients aged 20–85 years old who were scheduled for cardiovascular surgery from May 2018 to October 2018. The intent of this study was to evaluate whether salvaged blood with three different devices includes large enough quantities of heparin to influence activated clotting time in cardiovascular surgery. Between May and October 2018, 12 samples during heparinization were collected, and 12 samples of salvaged blood from 3 devices were collected after administrating protamine. The heparin concentration of the 24 samples was measured. All heparin concentrations in salvage blood sample from two devices was below the limit of measurement (0.10 IU/mL). Slightly measurable heparin was detected in salvaged blood sample from one device (mean 0.15 IU/mL). Salvaged blood during cardiovascular surgery intervention does not contain enough heparin to influence activated clotting time.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.82.3.449
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/823.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 82, 号 3, p. 449-455, 発行日 2020-08
著者版フラグ
値 publisher
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