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アイテム
Glymphatic imaging using MRI
http://hdl.handle.net/2237/00032625
http://hdl.handle.net/2237/00032625e4eb375f-b668-4779-bb20-5a67c8bb2cda
名前 / ファイル | ライセンス | アクション |
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Glymphatic_Imaging_using_MRI_Total_Final (2.7 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-09-14 | |||||
タイトル | ||||||
タイトル | Glymphatic imaging using MRI | |||||
言語 | en | |||||
著者 |
Taoka, Toshiaki
× Taoka, Toshiaki× Naganawa, Shinji |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | This is the peer reviewed version of the following article: [Taoka, T. and Naganawa, S. (2020), Glymphatic imaging using MRI. J Magn Reson Imaging, 51: 11-24. doi:10.1002/jmri.26892], which has been published in final form at [https://doi.org/10.1002/jmri.26892]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | glymphatic system | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | cerebrospinal fluid | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | interstitial fluid | |||||
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主題Scheme | Other | |||||
主題 | magnetic resonance imaging | |||||
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主題Scheme | Other | |||||
主題 | diffusion imaging | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | contrast media | |||||
抄録 | ||||||
内容記述 | In recent years, the existence of a mass transport system in the brain via cerebrospinal fluid (CSF) or interstitial fluid (ISF) has been suggested by many studies. The glymphatic system is hypothesized to be a waste clearance system of the CSF through the perivascular and interstitial spaces in the brain. Tracer studies have primarily been used to visualize or evaluate the waste clearance system in the brain, and evidence for this system has accumulated. The initial study that identified the glymphatic system was an in vivo tracer study in mice. In that study, fluorescent tracers were injected into the cisterna magna and visualized by two‐photon microscopy. MRI has also been used to evaluate glymphatic function primarily with gadolinium‐based contrast agents (GBCAs) as tracers. A number of GBCA studies evaluating glymphatic function have been conducted using either intrathecal or intravenous injections. Stable isotopes, such as 17O‐labeled water, may also be used as tracers since they can be detected by MRI. In addition to tracer studies, several other approaches have been used to evaluate ISF dynamics within the brain, including diffusion imaging. Phase contrast evaluation is a powerful method for visualizing flow within the CSF space. In order to evaluate the movement of water within tissue, diffusion‐weighted MRI represents another promising technique, and several studies have utilized diffusion techniques for the evaluation of the glymphatic system. This review will discuss the findings of these diffusion studies. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
内容記述 | ||||||
内容記述 | ファイル公開:2021-01-01 | |||||
言語 | ja | |||||
内容記述タイプ | Other | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Wiley | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプresource | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1002/jmri.26892 | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 1053-1807 | |||||
書誌情報 |
en : Journal of Magnetic Resonance Imaging 巻 51, 号 1, p. 11-24, 発行日 2020-01 |
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著者版フラグ | ||||||
値 | author |