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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 82(4)

Brain metastasis from extramammary Paget’s disease

https://doi.org/10.18999/nagjms.82.4.791
https://doi.org/10.18999/nagjms.82.4.791
2587d58f-3a17-4363-bef1-09cd0acce069
名前 / ファイル ライセンス アクション
19_Hanyu.pdf 19_Hanyu.pdf (27.6 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2020-11-26
タイトル
タイトル Brain metastasis from extramammary Paget’s disease
著者 Hanyu, Taketo

× Hanyu, Taketo

WEKO 102483

Hanyu, Taketo

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Fujitani, Shigeru

× Fujitani, Shigeru

WEKO 102484

Fujitani, Shigeru

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Ito, Ai

× Ito, Ai

WEKO 102485

Ito, Ai

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Mizutani, Nobuhiko

× Mizutani, Nobuhiko

WEKO 102486

Mizutani, Nobuhiko

Search repository
キーワード
主題Scheme Other
主題 brain metastasis
キーワード
主題Scheme Other
主題 extramammary Paget’s disease
キーワード
主題Scheme Other
主題 stereotactic radiosurgery
抄録
内容記述 Herein, we present a case of extramammary Paget’s disease with brain metastasis that was diagnosed pathologically for the first time in Japan. Moreover, invasive extramammary Paget’s disease (with distant metastasis) highly resistant to treatment. Only for brain metastasis, we may control the tumor by surgical resection and stereotactic radiosurgery (SRT) for the treatment of intracranial metastases was assessed.
An 76-year-old man was diagnosed with extramammary Paget’s disease of the vulva at nearby hospital. Surgical resection and sentinel lymph node dissection were then performed, and the patient received che-motherapy because multiple lymph node metastases were suspected. The patient’s response to chemotherapy was poor, and he was in the state of Progressive Disease. He complained of dyslexia and was referred to another hospital when he was 81 years old. Plain magnetic resonance imaging (MRI) was conducted, and two brain tumors in the vicinity of the left cerebellar tent were suspected.
In our hospital, gadolinium contrast-enhanced MRI was performed and showed a tumor in the cerebel-lum (left posterior temporal lobe) and another tumor under the tent (left cerebellar hemisphere). Significant edema was also noted. Based on these findings, the intracranial lesion was diagnosed as metastatic brain tumor. The pathological diagnosis was brain metastasis from extramammary Paget’s disease. Postoperative intracranial residual disease was treated with stereotactic radiosurgery. MRI showed that the size of the cerebellar lesions decreased, and no recurrence of cerebral lesions was observed. SRT for extracranial lymph node metastases was performed.
Mass reduction and SRT may be the best way to treat brain metastasis from extramammary Paget’s disease.
内容記述タイプ Abstract
出版者
出版者 Nagoya University Graduate School of Medicine, School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.82.4.791
ID登録タイプ JaLC
関連情報
関連タイプ isVersionOf
識別子タイプ URI
関連識別子 http://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/824.html
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
ISSN(Online)
収録物識別子タイプ ISSN
収録物識別子 2186-3326
書誌情報 Nagoya Journal of Medical Science

巻 82, 号 4, p. 791-798, 発行日 2020-11
著者版フラグ
値 publisher
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