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Difference in cardiovascular response during orthostatic stress in Parkinson’s disease and multiple system atrophy
http://hdl.handle.net/2237/00033213
http://hdl.handle.net/2237/00033213052db9e7-171f-42df-bd06-dede05d1f487
名前 / ファイル | ライセンス | アクション |
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Difference_in_cardiovascular_response_during_orthostatic_stress (1.0 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-12-17 | |||||
タイトル | ||||||
タイトル | Difference in cardiovascular response during orthostatic stress in Parkinson’s disease and multiple system atrophy | |||||
言語 | en | |||||
著者 |
Nakamura, Tomohiko
× Nakamura, Tomohiko× Suzuki, Masashi× Ueda, Masamichi× Harada, Yumiko× Hirayama, Masaaki× Katsuno, Masahisa |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | “This is a post-peer-review, pre-copyedit version of an article published in [Journal of Neural Transmission]. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00702-020-02241-8”. | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Parkinson’s disease | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Multiple system atrophy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cardiac response | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cardiac denervation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Total peripheral resistance | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Orthostatic hypotension | |||||
抄録 | ||||||
内容記述 | Although orthostatic hypotension is more prominent in multiple system atrophy (MSA) than in Parkinson’s disease (PD), there is no study comparing the degree of decrease in total peripheral resistance and cardiac response during orthostatic stress between both diseases. In this study, we examined whether there is a difference in cardiovascular response between MSA and PD. We examined the results of the head-up tilt test in 68 patients with MSA, 28 patients with cardiac non-denervated PD, and 70 patients with cardiac denervated PD whose total peripheral resistance after 60° tilting was lower than the value at 0°. Differences in cardiac output and blood pressure changes were compared against the decrease in total peripheral resistance. There was no difference in the degree of decrease in total peripheral resistance among the three groups. However, the slope of the regression line revealed that the increase in cardiac output against the change in total peripheral resistance was significantly lower in the MSA group than in the cardiac non-denervated and denervated PD groups, and that the decrease in systolic blood pressure against the change in total peripheral resistance was significantly greater in the MSA group than in the cardiac non-denervated and denervated PD groups. In MSA, the cardiac response during orthostatic stress is lower than that in PD, possibly underlying the fact that orthostatic hypotension is more prominent in MSA than in PD. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
内容記述 | ||||||
内容記述 | ファイル公開:2021/10/01 | |||||
言語 | ja | |||||
内容記述タイプ | Other | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Springer | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプresource | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
出版タイプ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1007/s00702-020-02241-8 | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0300-9564 | |||||
書誌情報 |
en : Journal of Neural Transmission 巻 127, 号 10, p. 1377-1386, 発行日 2020-10 |
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著者版フラグ | ||||||
値 | author |