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  1. C100 医学部/医学系研究科
  2. C100a 雑誌掲載論文
  3. 学術雑誌

Prospective Evaluation of Health-Related Quality of Life in Patients Undergoing Anterolateral Craniofacial Resection with Orbital Exenteration

http://hdl.handle.net/2237/00033494
http://hdl.handle.net/2237/00033494
332ed189-a7a5-47e1-a5d5-a09a576233cf
名前 / ファイル ライセンス アクション
system_appendPDF.pdf system_appendPDF (1.1 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2021-02-09
タイトル
タイトル Prospective Evaluation of Health-Related Quality of Life in Patients Undergoing Anterolateral Craniofacial Resection with Orbital Exenteration
言語 en
著者 Mukoyama, Nobuaki

× Mukoyama, Nobuaki

WEKO 103318

en Mukoyama, Nobuaki

Search repository
Nishio, Naoki

× Nishio, Naoki

WEKO 103319

en Nishio, Naoki

Search repository
Kimura, Hiroyuki

× Kimura, Hiroyuki

WEKO 103320

en Kimura, Hiroyuki

Search repository
Kishi, Shinichi

× Kishi, Shinichi

WEKO 103321

en Kishi, Shinichi

Search repository
Tokura, Tatsuya

× Tokura, Tatsuya

WEKO 103322

en Tokura, Tatsuya

Search repository
Kimura, Hiroki

× Kimura, Hiroki

WEKO 103323

en Kimura, Hiroki

Search repository
Hiramatsu, Mariko

× Hiramatsu, Mariko

WEKO 103324

en Hiramatsu, Mariko

Search repository
Maruo, Takashi

× Maruo, Takashi

WEKO 103325

en Maruo, Takashi

Search repository
Tsuzuki, Hidenori

× Tsuzuki, Hidenori

WEKO 103326

en Tsuzuki, Hidenori

Search repository
Fujii, Masazumi

× Fujii, Masazumi

WEKO 103327

en Fujii, Masazumi

Search repository
Iwami, Kenichiro

× Iwami, Kenichiro

WEKO 103328

en Iwami, Kenichiro

Search repository
Takanari, Keisuke

× Takanari, Keisuke

WEKO 103329

en Takanari, Keisuke

Search repository
Kamei, Yuzuru

× Kamei, Yuzuru

WEKO 103330

en Kamei, Yuzuru

Search repository
Ozaki, Norio

× Ozaki, Norio

WEKO 103331

en Ozaki, Norio

Search repository
Sone, Michihiko

× Sone, Michihiko

WEKO 103332

en Sone, Michihiko

Search repository
Fujimoto, Yasushi

× Fujimoto, Yasushi

WEKO 103333

en Fujimoto, Yasushi

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
キーワード
主題Scheme Other
主題 anterolateral craniofacial resection
キーワード
主題Scheme Other
主題 orbital exenteration
キーワード
主題Scheme Other
主題 quality of life
キーワード
主題Scheme Other
主題 skull base malignant tumor
キーワード
主題Scheme Other
主題 early psychiatric intervention
キーワード
主題Scheme Other
主題 hospital anxiety and depression scale
キーワード
主題Scheme Other
主題 medical outcomes study 8-items short form health survey
抄録
内容記述 Objective: This study was aimed to evaluate health-related quality of life in patients undergoing anterolateral craniofacial resection (AL-CFR) with orbital exenteration (OE) for malignant skull base tumors and to investigate the effects of early psychiatric intervention. Design: Present study is a prospective, observational study. Setting: The study took place at the hospital department. Participants: Twenty-six consecutive patients were selected who underwent AL-CFR with OE at our hospital between 2005 and 2015. Main Outcome Measures: Health-related quality of life was assessed preoperatively and 3, 6, 12, and 24 months after surgery using the Hospital Anxiety and Depression Scale (HADS) and medical outcomes study 8-items Short Form health survey (SF-8). In all cases, psychiatric intervention was organized by the consultation liaison psychiatry team preoperatively and postoperatively. Results: Ten (38.0%) of the 26 patients died and 16 (62.0%) were alive and disease-free at the end of the study. The 3-year overall and disease-free survival rates were 64.9% and 53.3%, respectively. Twenty-one patients (80.8%) developed psychiatric complications after surgery and needed treatment with psychotropic medication. Before surgery, 28% of patients had HADS scores ≥8 for anxiety and 20% had scores ≥8 for depression. Seven of the eight items in the SF-8 were significantly lower than those for the general Japanese population. However, scores for all the SF-8 items gradually improved during postoperative follow-up, reaching approximately 50 points, which is the national standard value, at 2 years after surgery. Conclusions: Craniofacial resection with OE was feasible and well tolerated in patients with malignant skull base tumors who received early psychiatric intervention to decrease the considerable psychological impact of this procedure.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 24 July 2019 (online)
言語 en
内容記述タイプ Other
出版者
言語 en
出版者 Georg Thieme Verlag
言語
言語 eng
資源タイプ
資源タイプresource http://purl.org/coar/resource_type/c_6501
タイプ journal article
出版タイプ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1055/s-0039-1694010
ISSN(print)
収録物識別子タイプ PISSN
収録物識別子 2193-6331
書誌情報 en : Journal of Neurological Surgery Part B: Skull Base

巻 81, 号 05, p. 585-593, 発行日 2020-10
著者版フラグ
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