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Sulfur depletion induces autophagy through Ecl1 family genes in fission yeast
http://hdl.handle.net/2237/00033521
http://hdl.handle.net/2237/000335211a978aec-e4ae-4beb-9e1c-07fef6987826
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
GENES_TO_CELLS_25_12_2020_825-830 (1.5 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2021-02-10 | |||||
| タイトル | ||||||
| タイトル | Sulfur depletion induces autophagy through Ecl1 family genes in fission yeast | |||||
| 言語 | en | |||||
| 著者 |
Shimasaki, Takafumi
× Shimasaki, Takafumi× Okamoto, Keisuke× Ohtsuka, Hokuto× Aiba, Hirofumi |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| 権利 | ||||||
| 権利情報 | This is the peer reviewed version of the following article: [Shimasaki, T, Okamoto, K, Ohtsuka, H, Aiba, H. Sulfur depletion induces autophagy through Ecl1 family genes in fission yeast. Genes Cells. 2020; 25: 825–830. https://doi.org/10.1111/gtc.12815], which has been published in final form at [https://doi.org/10.1111/gtc.12815]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | autophagy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | chronological lifespan | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Ecl1 family genes | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Schizosaccharomyces pombe | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | sulfur depletion | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Autophagy is an intracellular degradation system widely conserved among various species. Autophagy is induced by the depletion of various nutrients, and this degradation mechanism is essential for adaptation to such conditions. In this study, we demonstrated that sulfur depletion induces autophagy in the fission yeast Schizosaccharomyces pombe. Based on the finding that autophagy induced by sulfur depletion was completely abolished in a mutant in which the ecl1, ecl2 and ecl3 genes were deleted (Δecls), we report that these three genes are essential for the induction of autophagy by sulfur depletion. Furthermore, autophagy‐defective mutant cells exhibited poor growth and short lifespan (compared with wild‐type cells) under the sulfur‐depleted condition. These results indicated that the mechanism of autophagy is necessary for the appropriate adaptation to sulfur depletion. | |||||
| 言語 | en | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | ファイル公開：2021-12-01 | |||||
| 言語 | ja | |||||
| 出版者 | ||||||
| 出版者 | Wiley | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 出版タイプ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1111/gtc.12815 | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 1356-9597 | |||||
| 書誌情報 |
en : Genes to Cells 巻 25, 号 12, p. 825-830, 発行日 2020-12 |
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| 著者版フラグ | ||||||
| 値 | author | |||||
