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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 64(1-2)

Rescue of retinal function by macular translocation surgery in age-related macular degeneration and other diseases with subfoveal choroidal neovascularization

https://doi.org/10.18999/nagjms.64.1-2.1
https://doi.org/10.18999/nagjms.64.1-2.1
285fa117-1623-4360-9b81-48ee12f98ddd
名前 / ファイル ライセンス アクション
nj6411.pdf nj6411.pdf (101.6 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2006-02-03
タイトル
タイトル Rescue of retinal function by macular translocation surgery in age-related macular degeneration and other diseases with subfoveal choroidal neovascularization
著者 Terasaki, Hiroko

× Terasaki, Hiroko

WEKO 10036

Terasaki, Hiroko

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キーワード
主題Scheme Other
主題 Age-related macular degeneration
キーワード
主題Scheme Other
主題 high myopia
キーワード
主題Scheme Other
主題 choroidal neovascularization
キーワード
主題Scheme Other
主題 macular translocation
キーワード
主題Scheme Other
主題 vitrectomy
抄録
内容記述 Age-related macular degeneration (AMD) is the leading cause of legal blindness among the elderly. In AMD and some other macular diseases, subfoveal choroidal neovascularization (CNV) damages the underlying retinal pigment epithelium (RPE), and because retinal function is dependent on a healthy RPE, vision is markedly reduced by a subfoveal CNV. To treat such CNVs, macular translocation surgery has been performed to move the sensory retina from the damaged RPE to healthier RPE. At present, this surgery is the only possible treatment to improve the visual acuity of patients with subfoveal CNV. Macular translocation surgery involves the detachment of the entire retina from the RPE by a subretinal infusion of fluid and creating a 360° circumferential retinotomy followed by the rotation of the retina. Severe postoperative complications such as recurrent retinal detachment have been reported in about 30% of the cases after macular translocation. To determine the efficacy of this surgery, it is necessary to demonstrate an improvement in macular and overall retinal function objectively as well as subjectively. To this end, we have assessed the changes in visual function by measuring the visual acuity subjectively, and the macular function objectively by focal macular ERGs (FERGs). We shall show that there is an improvement in the FERGs in most patients after retinal translocation surgery but the full-field ERGs were reduced by about 30%. Thus, macular translocation surgery with 360-degree retinotomy may be feasible for macular function, although some degree of peripheral retinal function is lost.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.64.1-2.1
ID登録タイプ JaLC
書誌情報 Nagoya Journal of Medical Science

巻 64, 号 1-2, p. 1-9, 発行日 2001-05
フォーマット
application/pdf
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/5362
識別子タイプ HDL
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