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Mechanism of cartilage destruction in osteoarthritis
https://doi.org/10.18999/nagjms.65.3-4.73
https://doi.org/10.18999/nagjms.65.3-4.73e81e0ad9-2709-4e07-b923-2d3fbd04ee4e
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2006-02-09 | |||||
タイトル | ||||||
タイトル | Mechanism of cartilage destruction in osteoarthritis | |||||
著者 |
Ishiguro, Naoki
× Ishiguro, Naoki× Kojima, Toshihisa× Poole, A.Robin |
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キーワード | ||||||
主題Scheme | Other | |||||
主題 | osteoarthritis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | matrix metalloproteinase | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | aggrecan | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | type II collagen | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | aggrecanase | |||||
抄録 | ||||||
内容記述 | Osteoarthritis (OA) is one of the most common diseases among the elderly. For many years, OA was considered a normal result of the aging process with few treatment options. Remarkable progress in understanding OA cartilage has been achieved in recent years. The application of technical advances to clinical studies of chondrocytes and cartilage tissue metabolism will provide important new insights concerning the pathophysiology of OA and identify new therapeutic strategies to regulate and inhibit the degenerative process of OA. However, many problems remain unresolved. In this review we try to focus on recent advances in the field of cartilage metabolism and molecular markers to facilitate the determination of a patient's prognosis and the need for cartilage protective treatment. | |||||
内容記述タイプ | Abstract | |||||
出版者 | ||||||
出版者 | Nagoya University School of Medicine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.65.3-4.73 | |||||
ID登録タイプ | JaLC | |||||
書誌情報 |
Nagoya Journal of Medical Science 巻 65, 号 3-4, p. 73-84, 発行日 2002-11 |
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フォーマット | ||||||
application/pdf | ||||||
著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/5380 | |||||
識別子タイプ | HDL |