{"_buckets": {"deposit": "6c31e51f-674a-40e5-8638-0c4294c931e9"}, "_deposit": {"id": "5690", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "5690"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00005690"}, "item_10_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2000-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3", "bibliographicPageEnd": "248", "bibliographicPageStart": "237", "bibliographicVolumeNumber": "42", "bibliographic_titles": [{"bibliographic_title": "Development, Growth \u0026 Differentiation"}]}]}, "item_10_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "A Drosophila gene, Dwhn, encoding a putative transcriptional regulator with a DNA binding domain similar to that of mouse Winged\u2010helix nude (Whn) was cloned. Analyses of the phenotypes produced by a hypomorphic mutation and transgene expression suggested a role in cell fate decision during the differentiation of the compound eye, wing veins and bristles. During embryonic development, Dwhn expression started ubiquitously followed by more restricted expression in striking contrast to the expression patterns of other Drosophila forkhead (fkh) family genes whose local expression correlate well to their roles as local homeotic genes. This broad expression may correspond to the multiple defects in embryos homozygous for strong alleles, such as the defects in the formation of central and peripheral nervous systems, germ band retraction, head involution, and dorsal closure. The DNA binding specificity of Dwhn differed from that of Whn despite the strong sequence conservation in the DNA binding domain. Dwhn is the first invertebrate Whn\u2010like transcriptional regulator, and should provide insights into the basic functions and evolution of the whn family genes.", "subitem_description_type": "Abstract"}]}, "item_10_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/7296"}]}, "item_10_publisher_32": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Blackwell Synergy"}]}, "item_10_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "http://dx.doi.org/10.1046/j.1440-169x.2000.00509.x", "subitem_relation_type_select": "DOI"}}]}, "item_10_rights_12": {"attribute_name": "\u6a29\u5229", "attribute_value_mlt": [{"subitem_rights": "The definitive version is available at www.blackwell-synergy.com"}]}, "item_10_select_15": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_10_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0012-1592", "subitem_source_identifier_type": "ISSN"}]}, "item_10_text_14": {"attribute_name": "\u30d5\u30a9\u30fc\u30de\u30c3\u30c8", "attribute_value_mlt": [{"subitem_text_value": "application/pdf"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Sugimura, Isamu"}], "nameIdentifiers": [{"nameIdentifier": "15130", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Adachi-Yamada, Takashi"}], "nameIdentifiers": [{"nameIdentifier": "15131", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nishi, Yoshimi"}], "nameIdentifiers": [{"nameIdentifier": "15132", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nishida, Yasuyoshi"}], "nameIdentifiers": [{"nameIdentifier": "15133", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Dwhn_final_DGD.pdf", "filesize": [{"value": "2.0 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2000000.0, "url": {"label": "Dwhn_final_DGD.pdf", "url": "https://nagoya.repo.nii.ac.jp/record/5690/files/Dwhn_final_DGD.pdf"}, "version_id": "ce3054eb-7e76-40f5-b245-87009ddc17d5"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "Forkhead", "subitem_subject_scheme": "Other"}, {"subitem_subject": "HNF-3", "subitem_subject_scheme": "Other"}, {"subitem_subject": "development", "subitem_subject_scheme": "Other"}, {"subitem_subject": "nude gene", "subitem_subject_scheme": "Other"}, {"subitem_subject": "CNS", "subitem_subject_scheme": "Other"}, {"subitem_subject": "PNS", "subitem_subject_scheme": "Other"}, {"subitem_subject": "compound eye", "subitem_subject_scheme": "Other"}, {"subitem_subject": "dorsal closure", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "A Drosophila Winged-helix nude (Whn)-like transcription factor with essential functions throughout development", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "A Drosophila Winged-helix nude (Whn)-like transcription factor with essential functions throughout development"}]}, "item_type_id": "10", "owner": "1", "path": ["336/695/696"], "permalink_uri": "http://hdl.handle.net/2237/7296", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2007-02-09"}, "publish_date": "2007-02-09", "publish_status": "0", "recid": "5690", "relation": {}, "relation_version_is_last": true, "title": ["A Drosophila Winged-helix nude (Whn)-like transcription factor with essential functions throughout development"], "weko_shared_id": 3}