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Paracrine Factors from Cultured Cardiac Cells Promote Differentiation of Embryonic Stem Cells into Cardiac Myocytes
https://doi.org/10.18999/envm.47.45
https://doi.org/10.18999/envm.47.45e81c63ae-77b3-4875-bc9c-f6ad2e2f5127
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
45-47.pdf (230.3 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-04-05 | |||||
| タイトル | ||||||
| タイトル | Paracrine Factors from Cultured Cardiac Cells Promote Differentiation of Embryonic Stem Cells into Cardiac Myocytes | |||||
| 言語 | en | |||||
| 著者 |
Miwa, Keiko
× Miwa, Keiko× Lee, Jong-Kook× Hidaka, Kyoko× Shi, Rong-qian× Itoh, Gen× Morisaki, Takayuki× Kodama, Itsuo |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | embryonic stem cell | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | fluorescence-activated cell sorting | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | conditioned medium | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Embryonic stem (ES) cell-derived cardiac myocytes could be valid source for cell transplantation therapy. The primary goal of the present study is to explore the efficient method to obtain cardiac cells derived from ES cells. We examined the effects of conditioned medium from cultured cardiac cells of neonatal mouse on the differentiation of ES cells toward cardiac myocytes. When Nkx2.5-GFP knock-in ES cells were incubated in the medium extracted from cultured neonatal mouse ventricular myocytes, they showed more efficient differentiation to cardiac myocytes, compared with incubation in the control medium (6.8±1.6 vs 8.6±1.9%, n=4, p<0.05). Neonatal cultured myocytes may produce some paracrine factors which promotes ES cell differentiation to cardiac cells. | |||||
| 言語 | en | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 国立情報学研究所で電子化したコンテンツを使用している。 | |||||
| 言語 | ja | |||||
| 出版者 | ||||||
| 出版者 | Research Institute of Environmental Medicine, Nagoya University | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/envm.47.45 | |||||
| ID登録タイプ | JaLC | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0287-0517 | |||||
| 書誌情報 |
en : Environmental Medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University 巻 47, p. 45-47, 発行日 2003-12 |
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| フォーマット | ||||||
| 値 | application/pdf | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/7580 | |||||
| 識別子タイプ | HDL | |||||
