ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "8d93039b-6340-448e-9074-d058b0c62e61"}, "_deposit": {"id": "5972", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "5972"}, "status": "published"}, "_oai": {"id": "oai:nagoya.repo.nii.ac.jp:00005972", "sets": []}, "author_link": ["15911", "15912"], "item_1615768549627": {"attribute_name": "出版タイプ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_9_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2003-12", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "55", "bibliographicPageStart": "53", "bibliographicVolumeNumber": "47", "bibliographic_titles": [{"bibliographic_title": "Environmental Medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University", "bibliographic_titleLang": "en"}]}]}, "item_9_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Amiodarone is a potent antiarrhythmic agent in the treatment of the atrial fibrillation and flutter. However, underlying electrophysiological mechanism are not clarified yet. In the present study, we investigated the acute effects of amiodarone on the action potentials in rabbit atrial myocytes. Amiodarone (10μM) prolonged the action potential durations (APDs) at lower stimulation frequencies (e.g. 38±8 ms control vs. 45±6 ms amiodarone at 0.1 Hz, n=3, P\u003c0.05). In contrast, amiodarone shortened the APDs at higher frequencies (e.g. 81±11 ms control vs. 25±10 ms amiodarone at 3.0 Hz, n=3, P\u003c0.05). These results suggest that the antiarrhythmic action of amiodarone on atrial arrhythmias exhibits frequency-dependence.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_9_description_5": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "国立情報学研究所で電子化したコンテンツを使用している。", "subitem_description_language": "ja", "subitem_description_type": "Other"}]}, "item_9_identifier_60": {"attribute_name": "URI", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/2237/7589"}]}, "item_9_identifier_registration": {"attribute_name": "ID登録", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.18999/envm.47.53", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Research Institute of Environmental Medicine, Nagoya University", "subitem_publisher_language": "en"}]}, "item_9_select_15": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_9_source_id_7": {"attribute_name": "ISSN(print)", "attribute_value_mlt": [{"subitem_source_identifier": "0287-0517", "subitem_source_identifier_type": "PISSN"}]}, "item_9_text_14": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_text_value": "application/pdf"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Lu, Zhibo", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "15911", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kamiya, Kaichiro", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "15912", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-02-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "53-55.pdf", "filesize": [{"value": "238.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 238500.0, "url": {"label": "53-55.pdf", "objectType": "fulltext", "url": "https://nagoya.repo.nii.ac.jp/record/5972/files/53-55.pdf"}, "version_id": "858be83d-055e-44f8-ade5-bcc337678524"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "amiodarone", "subitem_subject_scheme": "Other"}, {"subitem_subject": "rabbit", "subitem_subject_scheme": "Other"}, {"subitem_subject": "atrial", "subitem_subject_scheme": "Other"}, {"subitem_subject": "action potential", "subitem_subject_scheme": "Other"}, {"subitem_subject": "frequency dependency", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Effects of Amiodarone on the Electrophysiological Characters of Rabbit Atrial Myocytes", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Effects of Amiodarone on the Electrophysiological Characters of Rabbit Atrial Myocytes", "subitem_title_language": "en"}]}, "item_type_id": "9", "owner": "1", "path": ["737"], "permalink_uri": "https://doi.org/10.18999/envm.47.53", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2007-04-06"}, "publish_date": "2007-04-06", "publish_status": "0", "recid": "5972", "relation": {}, "relation_version_is_last": true, "title": ["Effects of Amiodarone on the Electrophysiological Characters of Rabbit Atrial Myocytes"], "weko_shared_id": -1}
  1. F100 環境医学研究所
  2. F100b 紀要
  3. Environmental medicine : annual report of the Research Institute of Environmental Medicine
  4. 47

Effects of Amiodarone on the Electrophysiological Characters of Rabbit Atrial Myocytes

https://doi.org/10.18999/envm.47.53
https://doi.org/10.18999/envm.47.53
f8a7c85a-87c6-421c-9606-441ce35590a7
名前 / ファイル ライセンス アクション
53-55.pdf 53-55.pdf (238.5 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2007-04-06
タイトル
タイトル Effects of Amiodarone on the Electrophysiological Characters of Rabbit Atrial Myocytes
言語 en
著者 Lu, Zhibo

× Lu, Zhibo

WEKO 15911

en Lu, Zhibo

Search repository
Kamiya, Kaichiro

× Kamiya, Kaichiro

WEKO 15912

en Kamiya, Kaichiro

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
キーワード
主題Scheme Other
主題 amiodarone
キーワード
主題Scheme Other
主題 rabbit
キーワード
主題Scheme Other
主題 atrial
キーワード
主題Scheme Other
主題 action potential
キーワード
主題Scheme Other
主題 frequency dependency
抄録
内容記述 Amiodarone is a potent antiarrhythmic agent in the treatment of the atrial fibrillation and flutter. However, underlying electrophysiological mechanism are not clarified yet. In the present study, we investigated the acute effects of amiodarone on the action potentials in rabbit atrial myocytes. Amiodarone (10μM) prolonged the action potential durations (APDs) at lower stimulation frequencies (e.g. 38±8 ms control vs. 45±6 ms amiodarone at 0.1 Hz, n=3, P<0.05). In contrast, amiodarone shortened the APDs at higher frequencies (e.g. 81±11 ms control vs. 25±10 ms amiodarone at 3.0 Hz, n=3, P<0.05). These results suggest that the antiarrhythmic action of amiodarone on atrial arrhythmias exhibits frequency-dependence.
言語 en
内容記述タイプ Abstract
内容記述
内容記述 国立情報学研究所で電子化したコンテンツを使用している。
言語 ja
内容記述タイプ Other
出版者
言語 en
出版者 Research Institute of Environmental Medicine, Nagoya University
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
ID登録
ID登録 10.18999/envm.47.53
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ PISSN
収録物識別子 0287-0517
書誌情報 en : Environmental Medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University

巻 47, p. 53-55, 発行日 2003-12
フォーマット
application/pdf
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/7589
識別子タイプ HDL
戻る
0
views
See details
Views

Versions

Ver.1 2021-03-01 20:19:07.553001
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3