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Limited Association of Connexin43 and ZO-1 in the Intercalated Disks of Adult Rat Ventricular Myocrdium
https://doi.org/10.18999/envm.47.56
https://doi.org/10.18999/envm.47.5623cf7fb3-4323-4a9e-9a45-a70bbcbae9c5
名前 / ファイル | ライセンス | アクション |
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56-58.pdf (239.5 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2007-04-06 | |||||
タイトル | ||||||
タイトル | Limited Association of Connexin43 and ZO-1 in the Intercalated Disks of Adult Rat Ventricular Myocrdium | |||||
言語 | en | |||||
著者 |
Sasano, Chieko
× Sasano, Chieko× Takagishi, Yoshiko× Honjo, Haruo× Kamiya, Kaichiro× Kodama, Itsuo |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | gap junction | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cx43 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ZO-1 | |||||
抄録 | ||||||
内容記述 | Recent biochemical studies have suggested that zonula occludens-1 (ZO-1), a PDZ domain-containing protein may play an important role in targeting the major gap junction protein, Cx43 to the intercalated disk region of cardiac muscle. Information for in vivo is, however, still limited. We investigated the distribution of Cx43 and ZO-1 proteins in the ventricular myocardium of adult rats using high-resolution analysis with a confocal microscopy. Immunolabeling spots for Cx43 and ZO-1 were largely confined to the marked difference in the positions, Indicating low levels of colocalization of Cx43 and ZO-1 immunolabeled spots in the intercalated disks. These results suggest that ZO-1 does not play an important role in intercalated disk-targeting of Cx43 molecules in the normal ventricular myocardium. | |||||
言語 | en | |||||
内容記述タイプ | Abstract | |||||
内容記述 | ||||||
内容記述 | 国立情報学研究所で電子化したコンテンツを使用している。 | |||||
言語 | ja | |||||
内容記述タイプ | Other | |||||
出版者 | ||||||
言語 | en | |||||
出版者 | Research Institute of Environmental Medicine, Nagoya University | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/envm.47.56 | |||||
ID登録タイプ | JaLC | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0287-0517 | |||||
書誌情報 |
en : Environmental Medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University 巻 47, p. 56-58, 発行日 2003-12 |
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フォーマット | ||||||
application/pdf | ||||||
著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/7591 | |||||
識別子タイプ | HDL |