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METABOLIC SYNDROME DEFINED BY NEW CRITERIA IN JAPANESE IS ASSOCIATED WITH INCREASED LIVER ENZYMES AND C-REACTIVE PROTEIN
https://doi.org/10.18999/nagjms.70.1-2.1
https://doi.org/10.18999/nagjms.70.1-2.183c9db14-49de-40a3-a5f2-48c354d327a0
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
p01-09_Taki.pdf (282.7 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2008-04-07 | |||||
| タイトル | ||||||
| タイトル | METABOLIC SYNDROME DEFINED BY NEW CRITERIA IN JAPANESE IS ASSOCIATED WITH INCREASED LIVER ENZYMES AND C-REACTIVE PROTEIN | |||||
| 言語 | en | |||||
| 著者 |
Taki, Kentaro
× Taki, Kentaro× Nishio, Kazuko× Hamajima, Nobuyuki× Niwa, Toshimitsu |
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| アクセス権 | ||||||
| アクセス権 | open access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Metabolic syndrome | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Japanese | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Liver enzymes | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Inflammation | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Metabolic syndrome (MetS) is characterized by the presence of atherogenic risk factors, and is associated with a marked increase in the risk of cardiovascular disease. Recently, the criteria of MetS were newly defined in Japan.We examined the relationship between MetS and the various metabolic parameters in Japanese subjects. This study included 458 Japanese subjects undergoing medical checkups at Nagoya University Hospital. New criteria developed by the joint committee of eight Japanese medical societies for the clinical recognition of MetS were adopted. We examined the association between MetS and various metabolic parameters, including liver enzymes (alanine aminotransferase, ALT; gamma glutamyltransferase, GGT) and highly sensitive C-reactive protein (hsCRP). The mean overall prevalence of MetS was 8.7%(male: 12.9%; female: 2.2%, p=0.0001). MetS was significantly associated with elevated ALT (>45 IU/L) (OR: 3.37, 95% CI: 1.19–9.52, p<0.05) and GGT (>64 IU/L in males, >45 IU/L in females) (OR: 4.96, 95% CI: 2.31–10.66, p=0.0001), respectively. MetS was also significantly associated with elevated hsCRP (≥ 0.1 ng/mL) (OR: 2.77, 95% CI: 1.20–6.41, p<0.05). Thus, MetS was associated with elevated liver enzymes (especially, GGT), and inflammation (hsCRP). | |||||
| 言語 | en | |||||
| 出版者 | ||||||
| 出版者 | Nagoya University School of Medicine | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| ID登録 | ||||||
| ID登録 | 10.18999/nagjms.70.1-2.1 | |||||
| ID登録タイプ | JaLC | |||||
| ISSN（print） | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0027-7622 | |||||
| ISSN（Online） | ||||||
| 収録物識別子タイプ | EISSN | |||||
| 収録物識別子 | 2186-3326 | |||||
| 書誌情報 |
en : Nagoya Journal of Medical Science 巻 70, 号 1-2, p. 1-9, 発行日 2008-03 |
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| フォーマット | ||||||
| 値 | application/pdf | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
| URI | ||||||
| 識別子 | http://hdl.handle.net/2237/9646 | |||||
| 識別子タイプ | HDL | |||||
