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  1. C100 医学部/医学系研究科
  2. C100b 紀要
  3. Nagoya journal of medical science
  4. 70(3-4)

CONTROLS FOR MONITORING THE DETERIORATION OF STORED BLOOD SAMPLES IN THE JAPAN MULTI-INSTITUTIONAL COLLABORATIVE COHORT STUDY (J-MICC STUDY)

https://doi.org/10.18999/nagjms.70.3-4.107
https://doi.org/10.18999/nagjms.70.3-4.107
6d260b56-2794-46cb-91a6-233d5a4dde5c
名前 / ファイル ライセンス アクション
p107-115_Naito.pdf p107-115_Naito.pdf (84.0 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2008-09-22
タイトル
タイトル CONTROLS FOR MONITORING THE DETERIORATION OF STORED BLOOD SAMPLES IN THE JAPAN MULTI-INSTITUTIONAL COLLABORATIVE COHORT STUDY (J-MICC STUDY)
著者 NAITO, MARIKO

× NAITO, MARIKO

WEKO 24765

NAITO, MARIKO

Search repository
EGUCHI, HIDETAKA

× EGUCHI, HIDETAKA

WEKO 24766

EGUCHI, HIDETAKA

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OKADA, RIEKO

× OKADA, RIEKO

WEKO 24767

OKADA, RIEKO

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ISHIDA, YOSHIKO

× ISHIDA, YOSHIKO

WEKO 24768

ISHIDA, YOSHIKO

Search repository
NISHIO, KAZUKO

× NISHIO, KAZUKO

WEKO 24769

NISHIO, KAZUKO

Search repository
HISHIDA, ASAHI

× HISHIDA, ASAHI

WEKO 24770

HISHIDA, ASAHI

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WAKAI, KENJI

× WAKAI, KENJI

WEKO 24771

WAKAI, KENJI

Search repository
TAMAKOSHI, AKIKO

× TAMAKOSHI, AKIKO

WEKO 24772

TAMAKOSHI, AKIKO

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HAMAJIMA, NOBUYUKI

× HAMAJIMA, NOBUYUKI

WEKO 24773

HAMAJIMA, NOBUYUKI

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キーワード
主題Scheme Other
主題 Cohort study
キーワード
主題Scheme Other
主題 Blood samples
キーワード
主題Scheme Other
主題 Biomarkers
キーワード
主題Scheme Other
主題 Long-term storage
キーワード
主題Scheme Other
主題 Stability
抄録
内容記述 Cohort studies commonly store blood samples to measure the associations of biomarkers with disease risks for a long time after the study subjects are enrolled. To obtain valid measurements of the stored samples, monitoring their degree of deterioration is essential. The first stage of the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study launched in 2005 included a project to validate the quality of stored blood samples. This project will compare the measurements of representative molecules over different storage periods (1, 4, and 8 years after sampling, and when a nested case-control study is conducted), different storage temperatures (–80 and –150°C), and different separation conditions (temperature and time) before storage. For these purposes, 28 ml of peripheral blood from 10 people was sampled four times annually, using two tubes for serum and two EDTA -Na tubes for plasma. These samples were treated using the process adopted for the J-MIC study protocol, and stored in tubes containing 300 μl of serum or plasma labeled with two-dimensional bar codes. The sampling was started in 2006, and some of the specimens will be stored until the end of the J-MICC Study in 2035. The resulting findings will produce valuable information on the stability of the molecules, not only for the J-MICC Study, but also for other cohort studies.
内容記述タイプ Abstract
出版者
出版者 Nagoya University School of Medicine
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
ID登録
ID登録 10.18999/nagjms.70.3-4.107
ID登録タイプ JaLC
ISSN(print)
収録物識別子タイプ ISSN
収録物識別子 0027-7622
書誌情報 Nagoya Journal of Medical Science

巻 70, 号 3-4, p. 107-115, 発行日 2008-08
フォーマット
application/pdf
著者版フラグ
値 publisher
URI
識別子 http://hdl.handle.net/2237/10549
識別子タイプ HDL
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