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CONTROLS FOR MONITORING THE DETERIORATION OF STORED BLOOD SAMPLES IN THE JAPAN MULTI-INSTITUTIONAL COLLABORATIVE COHORT STUDY (J-MICC STUDY)
https://doi.org/10.18999/nagjms.70.3-4.107
https://doi.org/10.18999/nagjms.70.3-4.1076d260b56-2794-46cb-91a6-233d5a4dde5c
名前 / ファイル | ライセンス | アクション |
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p107-115_Naito.pdf (84.0 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2008-09-22 | |||||
タイトル | ||||||
タイトル | CONTROLS FOR MONITORING THE DETERIORATION OF STORED BLOOD SAMPLES IN THE JAPAN MULTI-INSTITUTIONAL COLLABORATIVE COHORT STUDY (J-MICC STUDY) | |||||
言語 | en | |||||
著者 |
NAITO, MARIKO
× NAITO, MARIKO× EGUCHI, HIDETAKA× OKADA, RIEKO× ISHIDA, YOSHIKO× NISHIO, KAZUKO× HISHIDA, ASAHI× WAKAI, KENJI× TAMAKOSHI, AKIKO× HAMAJIMA, NOBUYUKI |
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アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cohort study | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Blood samples | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Biomarkers | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Long-term storage | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Stability | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Cohort studies commonly store blood samples to measure the associations of biomarkers with disease risks for a long time after the study subjects are enrolled. To obtain valid measurements of the stored samples, monitoring their degree of deterioration is essential. The first stage of the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study launched in 2005 included a project to validate the quality of stored blood samples. This project will compare the measurements of representative molecules over different storage periods (1, 4, and 8 years after sampling, and when a nested case-control study is conducted), different storage temperatures (–80 and –150°C), and different separation conditions (temperature and time) before storage. For these purposes, 28 ml of peripheral blood from 10 people was sampled four times annually, using two tubes for serum and two EDTA -Na tubes for plasma. These samples were treated using the process adopted for the J-MIC study protocol, and stored in tubes containing 300 μl of serum or plasma labeled with two-dimensional bar codes. The sampling was started in 2006, and some of the specimens will be stored until the end of the J-MICC Study in 2035. The resulting findings will produce valuable information on the stability of the molecules, not only for the J-MICC Study, but also for other cohort studies. | |||||
言語 | en | |||||
出版者 | ||||||
出版者 | Nagoya University School of Medicine | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
ID登録 | ||||||
ID登録 | 10.18999/nagjms.70.3-4.107 | |||||
ID登録タイプ | JaLC | |||||
ISSN(print) | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 0027-7622 | |||||
ISSN(Online) | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 2186-3326 | |||||
書誌情報 |
en : Nagoya Journal of Medical Science 巻 70, 号 3-4, p. 107-115, 発行日 2008-08 |
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フォーマット | ||||||
値 | application/pdf | |||||
著者版フラグ | ||||||
値 | publisher | |||||
URI | ||||||
識別子 | http://hdl.handle.net/2237/10549 | |||||
識別子タイプ | HDL |